Changes

===== Psychological factors =====  

===== Psychological factors =====  

Passion, worry, fear, anger and grief can affect digestion leading to poor nutritional status. Hence blissful state of mind is needed for proper nutrition. Rai and Kar in their observational study showed that worries, fear and grief are major etiological factors for iron deficiency anemia. These factors cause significant reduction of serum and bone marrow, while inhibiting the process of erythropoiesis. The inflammatory mediators such as IL-6, hepcidin are mediators in this pathology originated from grief and fear.  

Passion, worry, fear, anger and grief can affect digestion leading to poor nutritional status. Hence blissful state of mind is needed for proper nutrition. Rai and Kar in their observational study showed that worries, fear and grief are major etiological factors for iron deficiency anemia. These factors cause significant reduction of serum and bone marrow, while inhibiting the process of erythropoiesis. The inflammatory mediators such as IL-6, hepcidin are mediators in this pathology originated from grief and fear.<ref>Rai Shalini, Kar Anukul C. A review of role of psychological factors in the etiopathogenesis of Pandu roga with reference to iron deficiency anemia.Ayu,2016 Jan-March,31(1):18-21. </ref>

===== Iatrogenic factors =====  

===== Iatrogenic factors =====