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==== ''Rajas–tamas'' affliction ====

==== ''Rajas–tamas'' affliction ====

The first factor, ''rajas - tamas'' affliction, signifies the role of mind in etio-pathology of apasmara. ''Rajas'' is a ''guna'' (tendency or attribute) responsible for the initiation of every kind of activity and symbolizes energy, while ''Tamas'' is the ''guna'' symbolizing inertia, dulling or stopping of activities. These two play an important role in the coordination of activities within the sequence of sense organs-mind-intellect-spirit, in the attainment of knowledge as well as to maintain the orientation of external world (consciousness). A ''rajas-tamas'' affliction, therefore, adversely impacts coordination of activities and perverts the mind and intellect, landing the patient into loss of orientation and consciousness. A “distressed” state of mind, caused by ''rajas-tamas'' affliction, is an important etiological factor responsible for various psychosomatic disorders such as epilepsy. Therefore, rehabilitating the ''rajas - tamas'' balance (and thus, achieving harmony between all the three ''gunas'') is of utmost importance in preventing the pathology and maintenance of health. Neurologically, initiation of action through neurotransmitters such as acetylcholine, while inhibition of action through dopamine can be categorized under ''rajas'' and ''tamas'' respectively. Synchronization of discharges in the cerebral region is a result of ''rajas-tamas'' balance. Disturbance in this ''rajas-tamas'' balance and depletion of ''sattva'' leads to hypersynchronization, resulting in seizures. Threshold of neuronal activity is due to balance between ''sattva, rajas'' and ''tamas''. It is ''sattva'' that maintains the normal threshold of neuronal activities. Decreased ''sattva'' and/or increased ''rajas'' and ''tamas'' can alter the threshold of neurons.  

The first factor, ''rajas - tamas'' affliction, signifies the role of mind in etio-pathology of apasmara. ''Rajas'' is a ''[[guna]]'' (tendency or attribute) responsible for the initiation of every kind of activity and symbolizes energy, while ''Tamas'' is the ''[[guna]]'' symbolizing inertia, dulling or stopping of activities. These two play an important role in the coordination of activities within the sequence of sense organs-mind-intellect-spirit, in the attainment of knowledge as well as to maintain the orientation of external world (consciousness). A ''rajas-tamas'' affliction, therefore, adversely impacts coordination of activities and perverts the mind and intellect, landing the patient into loss of orientation and consciousness. A “distressed” state of mind, caused by ''rajas-tamas'' affliction, is an important etiological factor responsible for various psychosomatic disorders such as epilepsy. Therefore, rehabilitating the ''rajas - tamas'' balance (and thus, achieving harmony between all the three ''[[guna]]s'') is of utmost importance in preventing the pathology and maintenance of health. Neurologically, initiation of action through neurotransmitters such as acetylcholine, while inhibition of action through dopamine can be categorized under ''rajas'' and ''tamas'' respectively. Synchronization of discharges in the cerebral region is a result of ''rajas-tamas'' balance. Disturbance in this ''rajas-tamas'' balance and depletion of ''sattva'' leads to hypersynchronization, resulting in seizures. Threshold of neuronal activity is due to balance between ''sattva, rajas'' and ''tamas''. It is ''sattva'' that maintains the normal threshold of neuronal activities. Decreased ''sattva'' and/or increased ''rajas'' and ''tamas'' can alter the threshold of neurons.

 

The state of mind afflicted due to ''rajas'' and ''tamas'' can be considered as ‘distressed mind’ observed as important causative factor for various psycho somatic disorders like epilepsy.

==== ''Sharira dosha'' vitiation ====

==== ''Sharira dosha'' vitiation ====