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→Research works on insomnia
==Research works on insomnia ==
==Research works on insomnia ==
Various research studies have shown the efficacy of herbal medications in the management of insomnia. The details of some of the herbal medications with proven efficacy and safety through clinical trials are given in the table.
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Table 1: Researched formulations in management of insomnia
Various research studies have shown the efficacy of herbal medications in the management of insomnia. The details of some of the herbal medications with proven efficacy and safety through clinical trials are given in the table.
Compound/ single drug Ingredients Dose/duration/ vehicle
Mamsyadi ghrita Ghee processed with Nardostachys jatamansi(jatamamsi), Convulvulus pluricaulis (shankhapushpi), Withania somnifera(ashwagandha),Valeriana wallichii (tagara) 20 g twice a day orally with luke warm water for 6 weeks.
'''Table 1: Researched formulations in management of insomnia'''
Tagaradi Kwatha Nardostachys jatamansi (jatamamsi), Convulvulus pluricaulis (shankhapushpi), Withania somnifera (ashwagandha), Valeriana wallichii (tagara), Bacopa monnieri (brahmi),Vitis vinifera (draksha), Picrorhiza kurrooa (katuki), Hedyotis corymbosa (parpataka), Aegle marmelos(bilwa),Premna Serratifolia/integrifolia(agnimantha), Oroxylum indicum(shyonaka), Stereospermum suaveolens(patala), Gmelina arborea (gambhari), Solanum indicum(bruhati), Solanum xanthocarpum(kantakari),Desmodium gangeticum(shalaparni), Uraria picta(prushniparni), Tribulus terrestris(gokshura), Cyperus rotundus (musta), Pterocarpus santalinus (raktachandana), Cassia fistula(aragwadha) 40gm/day (In two divided doses each of 20 gms) in decoction form for 6 weeks
{| class= "wikitable" |}
Parasikayavani capsule. Hyoscyamus niger (parasikayavani)-1/4 part and Nardostachys jatamansi (Jatamansi)-1 part, triturated 7 times in juice of Convulvulus pluricaulis (shankhapushpi) and 7 times in juice of Benincasa hispida (kushmanda) 5 Capsules, with luke warm water, at bed time, for 1 month.
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Apamargadi vati Achyranthes aspera (apamarga), Asteracantha longifolia (kokilaksha), Perstrophe bicalyculata Linn (kakajangha), Psoralia corylifolia (bakuchi) 1 gm trice a day, with buffalo milk, for 8 weeks.
!Compound/ single drug !! Ingredients !! Dose/duration/ vehicle
Powder of root of Piper longum(pippali moola) -- 2 gm twice a day with jaggery (guda), after food , for 4 weeks
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Leaf powder of Nardostachys jatamansi (Jatamansi) -- 3 gm powder with honey (5g), ½ hour before bed time for 4 weeks.
|Mamsyadi ghrita ||Ghee processed with Nardostachys jatamansi(jatamamsi), Convulvulus pluricaulis (shankhapushpi), Withania somnifera(ashwagandha),Valeriana wallichii (tagara) || 20 g twice a day orally with luke warm water for 6 weeks.
Powder of Citrus medica Linn(beejapura) leaves -- 3 gm powder with honey (5g), ½ hour before bed time for 4 weeks
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Insomrid tablet Withania somnifera (ashwagandha), Rauvolfia serpentina (sarpagandha), Nardostachys jatamansi (jatamamsi), Valeriana wallichii (tagara), Hyoscyamus niger (parasika yavani) 2 tab (each of 500 mg) in the morning after breakfast and night after the dinner with luke warm milk for 30 days.
|Tagaradi Kwatha ||Nardostachys jatamansi (jatamamsi), Convulvulus pluricaulis (shankhapushpi), Withania somnifera (ashwagandha), Valeriana wallichii (tagara), Bacopa monnieri (brahmi),Vitis vinifera (draksha), Picrorhiza kurrooa (katuki), Hedyotis corymbosa (parpataka), Aegle marmelos(bilwa),Premna Serratifolia/integrifolia(agnimantha), Oroxylum indicum(shyonaka), Stereospermum suaveolens(patala), Gmelina arborea (gambhari), Solanum indicum(bruhati), Solanum xanthocarpum(kantakari),Desmodium gangeticum(shalaparni), Uraria picta(prushniparni), Tribulus terrestris(gokshura), Cyperus rotundus (musta), Pterocarpus santalinus (raktachandana), Cassia fistula(aragwadha) || 40gm/day (In two divided doses each of 20 gms) in decoction form for 6 weeks
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|Parasikayavani capsule || Hyoscyamus niger (parasikayavani)-1/4 part and Nardostachys jatamansi (Jatamansi)-1 part, triturated 7 times in juice of Convulvulus pluricaulis (shankhapushpi) and 7 times in juice of Benincasa hispida (kushmanda)||5 Capsules, with luke warm water, at bed time, for 1 month.
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|Apamargadi vati || Achyranthes aspera (apamarga), Asteracantha longifolia (kokilaksha), Perstrophe bicalyculata Linn (kakajangha), Psoralia corylifolia (bakuchi) ||1 gm trice a day, with buffalo milk, for 8 weeks.
|-
|Powder of root of Piper longum(pippali moola) || -- ||2 gm twice a day with jaggery (guda), after food , for 4 weeks
|-
|Leaf powder of Nardostachys jatamansi (Jatamansi) || -- || 3 gm powder with honey (5g), ½ hour before bed time for 4 weeks.
|-
|Powder of Citrus medica Linn(beejapura) leaves || -- || 3 gm powder with honey (5g), ½ hour before bed time for 4 weeks
|-
|Insomrid tablet || Withania somnifera (ashwagandha), Rauvolfia serpentina (sarpagandha), Nardostachys jatamansi (jatamamsi), Valeriana wallichii (tagara), Hyoscyamus niger (parasika yavani)|| 2 tab (each of 500 mg) in the morning after breakfast and night after the dinner with luke warm milk for 30 days.
|}
Therapeutic procedures:
Therapeutic procedures:
• Buffalo’s milk (mahisha dugdha)
• Buffalo’s milk (mahisha dugdha)
• Ksheerabala taila
• Ksheerabala taila
The duration of the procedure done in the clinical trials ranges from 30-45 minutes daily for 2-3 weeks, preferably in morning. The temperature range of liquid was 38-40 degree Celsius. A clinical trial showed efficacy of lukewarm water as equal to medicated oil in shirodhara procedure. The combined therapy with oral medication and local procedures shows appreciable results in the management of insomnia.
The duration of the procedure done in the clinical trials ranges from 30-45 minutes daily for 2-3 weeks, preferably in morning. The temperature range of liquid was 38-40 degree Celsius. A clinical trial showed efficacy of lukewarm water as equal to medicated oil in shirodhara procedure. The combined therapy with oral medication and local procedures shows appreciable results in the management of insomnia.
==Theses works ==
==Theses works ==
1) Nirmal Dhamini A (2004): Role Manasa Bhavas in Anidra and its management with certain indigenous drugs and Shiro-Dhara, Department of Kayachikitsa, IPGT &RA, Jamnagar.
1) Nirmal Dhamini A (2004): Role Manasa Bhavas in Anidra and its management with certain indigenous drugs and Shiro-Dhara, Department of Kayachikitsa, IPGT &RA, Jamnagar.