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The type of body frame of a patient with metabolic syndrome should be considered. As per [[Ayurveda]] obese (sthula), lean (krisha) and medium (madhyama) are the three types of body frames. [Su.Sa. Sutra Shtana 35/33] These are the  physiological variations of body frame. As per blood parameters, a thin-built person can also be obese. They are called thin obese patients. There the patient is having adipose tissue ([[meda dhatu]]) vitiation. At the same time, an obese patient may not require any treatment because of excellent adipose tissue quality (meda sara). The management also varies according to body frames. Bringing Ayurvedic and modern concepts about metabolic syndrome can make the treatment easy.
 
The type of body frame of a patient with metabolic syndrome should be considered. As per [[Ayurveda]] obese (sthula), lean (krisha) and medium (madhyama) are the three types of body frames. [Su.Sa. Sutra Shtana 35/33] These are the  physiological variations of body frame. As per blood parameters, a thin-built person can also be obese. They are called thin obese patients. There the patient is having adipose tissue ([[meda dhatu]]) vitiation. At the same time, an obese patient may not require any treatment because of excellent adipose tissue quality (meda sara). The management also varies according to body frames. Bringing Ayurvedic and modern concepts about metabolic syndrome can make the treatment easy.
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==Quality of body tissues (dhatu sarata)==
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===Quality of body tissues (dhatu sarata)===
 
   
 
   
 
Sarata means the optimum quality of body tissues. It is one of the assessment parameters to check the health of tissues. Physician may sometimes make a wrong judgement by just looking at the patient. A patient having corpulent or a big physique may not be strong or healthy. On the other hand,  it is observed that some persons having small body and leanness are strong, like the tiny ants carrying a big load. This is why the optimum quality of tissues ([[dhatu]] sarata) shall be examined before understanding a patient's strength. [Cha.Sa. [[Vimana Sthana]] 8/115]
 
Sarata means the optimum quality of body tissues. It is one of the assessment parameters to check the health of tissues. Physician may sometimes make a wrong judgement by just looking at the patient. A patient having corpulent or a big physique may not be strong or healthy. On the other hand,  it is observed that some persons having small body and leanness are strong, like the tiny ants carrying a big load. This is why the optimum quality of tissues ([[dhatu]] sarata) shall be examined before understanding a patient's strength. [Cha.Sa. [[Vimana Sthana]] 8/115]
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Quality of tissue (sarata) and blood parameters should be assessed before treating a patient. The biomarkers used in modern medical practice are insufficient and often inappropriate to decide the patient's diagnosis, prognosis, and treatment. The same is true while applying them in diagnostic and research of [[Ayurveda]] perspectives.
 
Quality of tissue (sarata) and blood parameters should be assessed before treating a patient. The biomarkers used in modern medical practice are insufficient and often inappropriate to decide the patient's diagnosis, prognosis, and treatment. The same is true while applying them in diagnostic and research of [[Ayurveda]] perspectives.
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In most of the researches in obesity, weight is considered as the main parameter. However, it is a very superficial parameter. Weight reduction to make the obese person thin is a primary goal in general practice. However, the most crucial concern in treating an obese person is not to make the person thin but to transform an unhealthy obese person to a healthy obese person. [Su.Sa. Sutra Sthana 35/34] If the person has adipose tissue with optimum quality (meda sara), it is challenging to reduce weight. Similarly, in hyperhomocysteinemia, one should see whether the patient is with optimal quality of blood tissue (rakta sara), before treating the person. So while treating obesity and metabolic syndrome through [[Ayurveda]], the targets should be different, and the biomarkers should be more specific.  
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In most of the researches in obesity, weight is considered as the main parameter. However, it is a very superficial parameter. Weight reduction to make the obese person thin is a primary goal in general practice. However, the most crucial concern in treating an obese person is not to make the person thin but to transform an unhealthy obese person to a healthy obese person. [Su.Sa. Sutra Sthana 35/34] If the person has adipose tissue with optimum quality (meda sara), it is challenging to reduce weight. Similarly, in hyperhomocysteinemia, one should see whether the patient is with optimal quality of blood tissue (rakta sara), before treating the person. So while treating obesity and metabolic syndrome through [[Ayurveda]], the targets should be different, and the biomarkers should be more specific.
    
==Selection of biomarker==
 
==Selection of biomarker==

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