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Line 161: − [[File:Obesity_patogenesis.JPG|500px|'''Figure 2: Pathogenesis of Obesity'''|thumb]]
→Pathogenesis
===Pathogenesis===
===Pathogenesis===
[[File:Obesity_patogenesis.JPG|500px|'''Figure 2: Pathogenesis of Obesity'''|thumb]]
Due to the causative factors, the adipose tissue ([[meda dhatu]]) only is nourished. This leads to obesity. The other tissues ([[dhatu]]) do not get nourishment. It results in laxity (shaithilya) in each body tissue. This leads to a shortening of life span. [Cha.Sa. [[Sutra Sthana]] 21/3] This laxity is also seen in obstinate urinary disorders, including diabetic mellitus (prameha).
Due to the causative factors, the adipose tissue ([[meda dhatu]]) only is nourished. This leads to obesity. The other tissues ([[dhatu]]) do not get nourishment. It results in laxity (shaithilya) in each body tissue. This leads to a shortening of life span. [Cha.Sa. [[Sutra Sthana]] 21/3] This laxity is also seen in obstinate urinary disorders, including diabetic mellitus (prameha).
In pathogenesis of prameha, the [[kapha]][[dosha]] and fat/adipose tissue ([[meda dhatu]]) mix with muscle ([[mamsa dhatu]]) and body fluids (kleda) which are already excessive in quantity. [Cha.Sa.[[Nidana Sthana]] 4/8] The disease prameha can be considered as a prototype for all metabolic disorders. So with [[meda dhatu]] and [[mamsa dhatu]], kleda should also be considered in metabolic disorders. The laxity occurs due to excess accumulation of kleda in body tissues. It results in oozing or discharge (abishyandana) into body channels. This creates low-grade inflammation at cellular level. The pathogenesis is as shown in figure 2.
In pathogenesis of prameha, the [[kapha]][[dosha]] and fat/adipose tissue ([[meda dhatu]]) mix with muscle ([[mamsa dhatu]]) and body fluids (kleda) which are already excessive in quantity. [Cha.Sa.[[Nidana Sthana]] 4/8] The disease prameha can be considered as a prototype for all metabolic disorders. So with [[meda dhatu]] and [[mamsa dhatu]], kleda should also be considered in metabolic disorders. The laxity occurs due to excess accumulation of kleda in body tissues. It results in oozing or discharge (abishyandana) into body channels. This creates low-grade inflammation at cellular level. The pathogenesis is as shown in figure 2.
====Role of body fluids (kleda)====
====Role of body fluids (kleda)====