Changes

==Etymology and derivation==

==Etymology and derivation==

The word guna is derived from the root ‘gunaamantrane’, which means to invite. That which attracts or invites towards a particular object is called its guna[Vachaspatyam].

The word guna is derived from the root ‘guna amantrane’, which means to invite. That which attracts or invites towards a particular object is called its guna. [Vachaspatyam]

==Definition==

==Definition==

Total 41 guna are explained in Ayurveda. They are classified under the following headings[Cha.Sa.[[Sutra Sthana]] 1/49]

Total 41 guna are explained in Ayurveda. They are classified under the following headings[Cha.Sa.[[Sutra Sthana]] 1/49]

*Physical properties (shariraguna): These are 20 in number.

*Physical properties (sharira guna): These are 20 in number.

*General properties (samanyaguna): These are 10 in number.

*General properties (samanya guna): These are 10 in number.

*Spiritual properties (adhyatmikaguna): These are 06 in number.

*Spiritual properties (adhyatmika guna): These are 06 in number.

*Properties of objects of senses (indriyartha/ vishishtaguna): These are 05 in number.

*Properties of objects of senses (indriyartha/ vishishta guna): These are 05 in number.

===Physical properties (shariraguna)===

===Physical properties (sharira guna)===

There are twenty physical properties which form ten pairs with their opposites. Each property has a specific fundamental constitution. The property shows biological effects through medium of a substance. The properties (guna) have inseparable concomitance (samavaya) with substance. Following table shows details about fundamental constitution, biological effects of each property with their applications in treatment.

There are twenty physical properties which form ten pairs with their opposites. Each property has a specific fundamental constitution. The property shows biological effects through medium of a substance. The properties (guna) have inseparable concomitance (samavaya) with substance. Following table shows details about fundamental constitution, biological effects of each property with their applications in treatment.

! Serial No !! Physical Property (guna) !! Fundamental constitution  !! Effect on [[dosha]] !! Biological effect !! Application in treatment !! Example

! Serial No !! Physical Property (guna) !! Fundamental constitution  !! Effect on [[dosha]] !! Biological effect !! Application in treatment !! Example

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| | 1 ||Heavy (guru)|| [[Prithvi]],[[Jala]] || Increases [[Kapha]], Pacifies [[Vata]] || Produces heaviness(gaurava), increases excreta (mala) and coats the body channels (srotasupalepa), nourishes and increases mass, density  || Nourishing therapy([[brimhana]]), Oleation therapy ([[snehana]]), Sudation therapy ([[swedana]]) ||Black gram (Masha) etc.  

| | 1 ||Heavy (guru)|| [[Prithvi]],[[Jala]] || Increases [[Kapha]], Pacifies [[Vata]] || Produces heaviness(gaurava), increases excreta (mala) and coats the body channels (srotas upalepa), nourishes and increases mass, density  || Nourishing therapy([[brimhana]]), Oleation therapy ([[snehana]]), Sudation therapy ([[swedana]]) ||Black gram (Masha) etc.  

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| | 2 || Light (laghu)|| [[Vayu]] , [[Akasha]] ,  [[Agni]] || Increases [[Vata]], Pacifies [[Kapha]] || Reduces weight and volume of (lekhana) excreta (mala), clears the channels of the body ([[srotas]]), enhances enthusiasm, weakens, wound healing  || Reducing therapy ([[langhana]]), Drying therapy ([[rukshana]]), Styptic therapy ([[stambhana]]), Scrapping therapy (lekhana), Scarification (vranalekhana) || Hot water, Green gram (Mudga)

| | 2 || Light (laghu)|| [[Vayu]] , [[Akasha]] ,  [[Agni]] || Increases [[Vata]], Pacifies [[Kapha]] || Reduces weight and volume of (lekhana) excreta (mala), clears the channels of the body ([[srotas]]), enhances enthusiasm, weakens, wound healing  || Reducing therapy ([[langhana]]), Drying therapy ([[rukshana]]), Styptic therapy ([[stambhana]]), Scrapping therapy (lekhana), Scarification (vranalekhana) || Hot water, Green gram (Mudga)

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Rough (karkasha) property is mentioned by Sushruta instead of coarse (khara). He added quickly acting(ashukari), pleasant odour (sugandha), foul smell (durgandha), pervading (vyavayi) and expanding by destroying body tissues (vikashi) in the list of properties[Su.Sa.Su. 46/515-524].  Dehydrated (shushka) property is added by Bhavamishra<ref>P.V.Sharma, Dravyaguna-vijnana Vol 1. Varanasi: Chaukhambhabharati academy;2006. Section 2,chapter 1 Guna;p.153.</ref>.

Rough (karkasha) property is mentioned by Sushruta instead of coarse (khara). He added quickly acting(ashukari), pleasant odour (sugandha), foul smell (durgandha), pervading (vyavayi) and expanding by destroying body tissues (vikashi) in the list of properties[Su.Sa.Su. 46/515-524].  Dehydrated (shushka) property is added by Bhavamishra.<ref>P.V.Sharma, Dravyaguna-vijnana Vol 1. Varanasi: Chaukhambhabharati academy;2006. Section 2,chapter 1 Guna;p.153.</ref>  

Cold(sheeta), hot (ushna), unctuous (snigdha), dry (ruksha), non-slimy (vishada), slimy (pichchila), heavy (guru), light (laghu), soft (mridu) and sharp (tikshna) show specific capacity for specific functions,hence they are also termed as ‘active properties’ (karmanyaguna) [Rasavaisheshika]<ref>P.V.Sharma, Dravyaguna-vijnana Vol 1. Varanasi: Chaukhambhabharati academy;2006. Section 2,chapter 1 Guna;p.152.</ref>

Cold(sheeta), hot (ushna), unctuous (snigdha), dry (ruksha), non-slimy (vishada), slimy (pichchila), heavy (guru), light (laghu), soft (mridu) and sharp (tikshna) show specific capacity for specific functions,hence they are also termed as ‘active properties’ (karmanyaguna) [Rasavaisheshika]<ref>P.V.Sharma, Dravyaguna-vijnana Vol 1. Varanasi: Chaukhambhabharati academy;2006. Section 2,chapter 1 Guna;p.152.</ref>

   

   

===General properties (samanyaguna)===

=== General properties (samanya guna) ===

These properties can be assessed by their effects or relative actions on more than one substance. The properties are essential for assessment in clinical practice and judgment. [Cha.Sa.[[Sutra Sthana]] 26/35].

These properties can be assessed by their effects or relative actions on more than one substance. The properties are essential for assessment in clinical practice and judgment. [Cha.Sa.[[Sutra Sthana]] 26/35].

! Serial No !! General property !! Effect and assessment !! Example

! Serial No !! General property !! Effect and assessment !! Example

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| | 1 || Superiority/Dominance (paratva) || It shows superiority or excellence of some substance over other. Dominance of a principle is also assessed || Amalaki is superior anti-ageing (vayasthapana)drug over other [Cha.Sa.[[Sutra Sthana]] 25/40]; Dominance of dosha in fundamental constitution(prakriti) and disease.

| | 1 || Superiority/Dominance (paratva) || It shows superiority or excellence of some substance over other. Dominance of a principle is also assessed || Amalaki is superior anti-ageing (vayasthapana)drug over other [Cha.Sa.[[Sutra Sthana]] 25/40]; Dominance of [[dosha]] in fundamental constitution ([[prakriti]]) and disease.

|-

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| | 2 || Inferiority/dormant (aparatva) || It shows the substance with inferior or dormant quality || Sheep’s milk is inferior in quality for health in comparison to other varieties of milk.[Cha.Sa.[[Sutra Sthana]] 25/40]

| | 2 || Inferiority/dormant (aparatva) || It shows the substance with inferior or dormant quality || Sheep’s milk is inferior in quality for health in comparison to other varieties of milk.[Cha.Sa.[[Sutra Sthana]] 25/40]

These properties are important in view of research perspectives. The comparative studies (para-aparatva), analytical studies and reasoning (yukti),statistical analysis (sankhya), combination in multi drug therapy (samyoga), pharmaceutical processing (samskara), long term follow up studies (abhyasa) are essential components of research.

These properties are important in view of research perspectives. The comparative studies (para-aparatva), analytical studies and reasoning (yukti),statistical analysis (sankhya), combination in multi drug therapy (samyoga), pharmaceutical processing (samskara), long term follow up studies (abhyasa) are essential components of research.

===Spiritual properties (adhyatmikaguna)===

=== Spiritual properties (adhyatmika guna)===

These properties are related to psycho-spiritual aspects of human being. These are presented through mind (mana) and can be assessed subjectively.  

These properties are related to psycho-spiritual aspects of human being. These are presented through mind (mana) and can be assessed subjectively.  

#Perseverance (prayatna)

#Perseverance (prayatna)

===Properties of objects of sense organs (indriyarthaguna)===

=== Properties of objects of sense organs (indriyartha guna)===

These properties are based upon sensory perception of senses. It represents the fundamental constituent also. These can be assessed subjectively as well as objectively.

These properties are based upon sensory perception of senses. It represents the fundamental constituent also. These can be assessed subjectively as well as objectively.

#Odour (gandha) property of olfactory senses (ghranendriya) and represents [[Prithvi mahabhuta]]

#Odour (gandha) property of olfactory senses (ghranendriya) and represents [[Prithvi mahabhuta]]

Along with this, Acharya Vagbata considers one more classification of guna that is mahaguna. [A.S.Su.1/29]

Along with this,one more classification of guna that is mahaguna is considered. [A.S.Su.1/29]

===Fundamental universal properties(Mahaguna)===

 

=== Fundamental universal properties (Mahaguna) ===

   

   

These three are produced from the material nature during primitive evolutionary process of the Universe (prakriti). These are also termed as primary attributes of mind.[SAT-A.126]<ref name=namstp />

These three are produced from the material nature during primitive evolutionary process of the Universe (prakriti). These are also termed as primary attributes of mind.[SAT-A.126]<ref name=namstp />

In human beings, these are represented in psychological plane as purest quality, initiator and regulator of all activities respectively. Sattva is pure form of mind, while rajas and tamas are causative factors for psychiatric disorders[Cha.Sa. [[Sutra Sthana]] 1/57]. These three guna connect soul ([[atma]]) with physical body. The eternal living entity ([[atma]]) is conditioned by these three modes of goodness, passion and ignorance<ref>Bhaktivedanta Swami Prabhupada. Bhagavad-Gita As it is. Chapter 14.6. 2008. Bhaktivedanta book trust. Pg 607 </ref>. Salvation (moksha) is attained after freedom from all these properties.

In human beings, these are represented in psychological plane as purest quality, initiator and regulator of all activities respectively. Sattva is pure form of mind, while rajas and tamas are causative factors for psychiatric disorders[Cha.Sa. [[Sutra Sthana]] 1/57]. These three guna connect soul ([[atma]]) with physical body. The eternal living entity ([[atma]]) is conditioned by these three modes of goodness, passion and ignorance<ref>Bhaktivedanta Swami Prabhupada. Bhagavad-Gita As it is. Chapter 14.6. 2008. Bhaktivedanta book trust. Pg 607 </ref>. Salvation (moksha) is attained after freedom from all these properties.

==Relation with [[mahabhuta]] and [[dosha]]==

====Relation with [[mahabhuta]] and [[dosha]]====

 

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[Su.Sa. Sha 1/20 with Dallhana commentary]

[Su.Sa. Sha 1/20 with Dallhana commentary]

==Relation with [[dosha]]==

====Relation with [[dosha]]====

   

   

The physical (sharira) and psychological (manas) planes are inter-connected to each other. Sattva guna in psychological plane is related to [[pitta]] [[dosha]]; rajas is related to [[vata]][[dosha]] and tamas is related with [[kapha]][[dosha]]. Accordingly, the physical and psychological activities are regulated.

The physical (sharira) and psychological (manas) planes are inter-connected to each other. Sattva guna in psychological plane is related to [[pitta]] [[dosha]]; rajas is related to [[vata]][[dosha]] and tamas is related with [[kapha]][[dosha]]. Accordingly, the physical and psychological activities are regulated.

 

==Properties of fundamental elements ([[panchamahabhuta]])==

 

===Properties of fundamental elements ([[panchamahabhuta]])===

   

   

The five fundamental elements possess specific properties and show effects.   

The five fundamental elements possess specific properties and show effects.   

[Cha.Sa.[[Sutra Sthana]] 26/11]

[Cha.Sa.[[Sutra Sthana]] 26/11]

==Properties of [[dosha]]==

=== Properties of [[dosha]] ===

   

   

The effects of [[dosha]] on body are caused due to their properties.  

The effects of [[dosha]] on body are caused due to their properties.  

[Cha.Sa.[[Sutra Sthana]] 1/59-61]

[Cha.Sa.[[Sutra Sthana]] 1/59-61]

==Properties of [[dhatu]]==

=== Properties of [[dhatu]] ===

 

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The body components show actions according to their properties. These properties are considered while treating abnormal states<ref>Nanal R.M. Sapta dhatu and shariraguna (Marathi). In MadhujivanaShariraGunaVisheshanka (1993). Nanal Publications.pg.88-91. </ref>

The body components show actions according to their properties. These properties are considered while treating abnormal states<ref>Nanal R.M. Sapta dhatu and shariraguna (Marathi). In MadhujivanaShariraGunaVisheshanka (1993). Nanal Publications.pg.88-91. </ref>

==Properties and tastes==

 

=== Properties and tastes ===

The substances with specific tastes (rasa) possess variable degrees of properties as below:  

The substances with specific tastes (rasa) possess variable degrees of properties as below:  

These are rationally applied in treatment.  

These are rationally applied in treatment.  

==Potency (veerya)==

=== Potency (veerya) ===

The potency of a substance depends on the property it possesses. All substances are divided into two main categories viz. hot (ushna) and cold (sheeta) based upon their potency. [A.H.Su. 1/17]

The potency of a substance depends on the property it possesses. All substances are divided into two main categories viz. hot (ushna) and cold (sheeta) based upon their potency. [A.H.Su. 1/17]

==Seasons and predominance of properties==

 

=== Seasons and predominance of properties ===

   

   

During hot season, the sharp (tikshna), hot (ushna) and dry (ruksha) properties are prevalent in environmental conditions. Cold (sheeta) and unctuous (snigdha) properties are predominantly present in cold season [A.H.Su.3/5]. These changes affect human biology and produces respective effects accordingly. The seasonal factor (kala) shall be considered in diagnosis and treatment.  

During hot season, the sharp (tikshna), hot (ushna) and dry (ruksha) properties are prevalent in environmental conditions. Cold (sheeta) and unctuous (snigdha) properties are predominantly present in cold season [A.H.Su.3/5]. These changes affect human biology and produces respective effects accordingly. The seasonal factor (kala) shall be considered in diagnosis and treatment.  

==Variations in properties==

=== Variations in properties ===

   

   

Some properties are influenced by effect of time, environmental factors etc. The substance may lose its properties due to influence of other factors. The freshly collected grains are heavy to digest (guru), but in due course of time, the grains become light to digest (laghu). [Chakrapani on Cha.Sa.[[Vimana Sthana]] 1/22(2)]

Some properties are influenced by effect of time, environmental factors etc. The substance may lose its properties due to influence of other factors. The freshly collected grains are heavy to digest (guru), but in due course of time, the grains become light to digest (laghu). [Chakrapani on Cha.Sa.[[Vimana Sthana]] 1/22(2)]

   

   

==Different interactions of properties==

=== Different interactions of properties ===

   

   

A substance may inherently possess opposite properties and show different actions accordingly. For example, Tinospora cordifolia shows properties of sweet (madhura) post digestion effect and hot potency (ushna veerya). These two are opposite in effect, however tinospora pacify [[pitta]] [[dosha]] due to its sweet effect and [[kapha]] [[dosha]] due to its hot potency. The effect of a substance is essentially observed after its interaction with human biological components. In case of interactions, the dominant property shows major impact, while the recessive property does not show any impact or shows mild effect [AH.Su 9/24].

A substance may inherently possess opposite properties and show different actions accordingly. For example, Tinospora cordifolia shows properties of sweet (madhura) post digestion effect and hot potency (ushna veerya). These two are opposite in effect, however tinospora pacify [[pitta]] [[dosha]] due to its sweet effect and [[kapha]] [[dosha]] due to its hot potency. The effect of a substance is essentially observed after its interaction with human biological components. In case of interactions, the dominant property shows major impact, while the recessive property does not show any impact or shows mild effect [AH.Su 9/24].

==Importance of knowledge of guna==

== Importance of knowledge of guna ==

Knowledge of guna is essential in every field to define standards. The actions or effects of each substance are caused due to its properties (guna) due to inseparable concomitance[Cha.Sa. [[Sutra Sthana]] 1/50]. The knowledge about property of an object is possible through analyzing its actions only[Su.Sa.Su.46/514]. Guna is the only principle which explains the drug activity. This is to be assessed objectively through action of that drug. The taste, potency and post digestion effect (vipaka) are the different expressions of guna only<ref>KarraNishteswar, Importance of guna amongst rasapanchaka. IAMJ [Internet]. 2013 [cited 2020 May 05]; Available from:http://www.iamj.in/posts/images/upload/IAMJ_01.05.01.pdf</ref>.  

Knowledge of guna is essential in every field to define standards. The actions or effects of each substance are caused due to its properties (guna) due to inseparable concomitance[Cha.Sa. [[Sutra Sthana]] 1/50]. The knowledge about property of an object is possible through analyzing its actions only[Su.Sa.Su.46/514]. Guna is the only principle which explains the drug activity. This is to be assessed objectively through action of that drug. The taste, potency and post digestion effect (vipaka) are the different expressions of guna only<ref>KarraNishteswar, Importance of guna amongst rasapanchaka. IAMJ [Internet]. 2013 [cited 2020 May 05]; Available from:http://www.iamj.in/posts/images/upload/IAMJ_01.05.01.pdf</ref>.  

===Importance in prevention===

=== Importance in prevention ===

Heaviness and lightness in relation to digestibility of food items is considered to decide appropriate quantity of food and preserve the equilibrium state of digestion and metabolism (agni) [Cha.Sa[[Sutra Sthana]] 5/6].

Heaviness and lightness in relation to digestibility of food items is considered to decide appropriate quantity of food and preserve the equilibrium state of digestion and metabolism (agni) [Cha.Sa[[Sutra Sthana]] 5/6].

In order to preserve health, one shall follow the diet and regimens opposite to the qualities of the habitat and causative factors of the diseases prevalent in that region. E.g. if the person belongs to marshy area, which is predominant in oiliness (sneha), heaviness (gaurava) etc. properties, then he shall follow the diet possessing the properties dryness, lightness etc. [Cha.Sa. [[Sutra Sthana]] 6/50].

In order to preserve health, one shall follow the diet and regimens opposite to the qualities of the habitat and causative factors of the diseases prevalent in that region. E.g. if the person belongs to marshy area, which is predominant in oiliness (sneha), heaviness (gaurava) etc. properties, then he shall follow the diet possessing the properties dryness, lightness etc. [Cha.Sa. [[Sutra Sthana]] 6/50].

===Importance in diagnosis===

=== Importance in diagnosis ===

Properties (guna) are fundamental part of all aspects of management. In diagnosis and treatment of disease, the body components are assessed in terms of its normal and abnormal properties. Thus, guna are tools for assessment.

Properties (guna) are fundamental part of all aspects of management. In diagnosis and treatment of disease, the body components are assessed in terms of its normal and abnormal properties. Thus, guna are tools for assessment.

Guna of a substance shall be understood properly to know cause, pathogenesis and treatment of a disease. Some examples are as given below:

Guna of a substance shall be understood properly to know cause, pathogenesis and treatment of a disease. Some examples are as given below:

   

   

Excess consumption of diet and lifestyle having similar properties to [[dosha]] and opposite to [[dhatu]] are causative factors for vitiation of channels of transport and transformation of body constituents (srotasa)[Cha.Sa. [[Vimana Sthana]]5/23][AH.Sha.3/44].

Excess consumption of diet and lifestyle having similar properties to [[dosha]] and opposite to [[dhatu]] are causative factors for vitiation of channels of transport and transformation of body constituents (srotasa)[Cha.Sa. [[Vimana Sthana]] 5/23] [A.H.Sha.3/44].

Excess use of substances having dry and cold property can cause [[vata]] dominant diseases[Cha.Sa. [[Chikitsa Sthana]]28/15], exposure to hot substances causes hemorrhagic disorders (raktapitta) and consumption of unctuous substance can cause obstinate urinary diseases (prameha).

Excess use of substances having dry and cold property can cause [[vata]] dominant diseases[Cha.Sa. [[Chikitsa Sthana]]28/15], exposure to hot substances causes hemorrhagic disorders (raktapitta) and consumption of unctuous substance can cause obstinate urinary diseases (prameha).

   

   

In pathogenesis of abdominal lumps and tumors (gulma), the body channels are hardened due to dryness (ruksha)[Cha.Sa. [[Nidana Sthana]] 3/7]. Skin becomes excessively dry or excessively smooth in skin diseases due to increased dryness of [[vata]][[dosha]] and unctuousness of [[kapha]][[dosha]] respectively.[ Cha.Sa. [[Chikitsa Sthana]]7/34-36].

In pathogenesis of abdominal lumps and tumors (gulma), the body channels are hardened due to dryness (ruksha)[Cha.Sa. [[Nidana Sthana]] 3/7]. Skin becomes excessively dry or excessively smooth in skin diseases due to increased dryness of [[vata]][[dosha]] and unctuousness of [[kapha]][[dosha]] respectively.[ Cha.Sa. [[Chikitsa Sthana]] 7/34-36].

Mobility (chalatva) is a property of [[vata]][[dosha]]. If this property is lost in a subject, that can be inferred as an abnormal reduction in [[vata]][[dosha]]. This type of properties can be assessed in patients in the form of signs and symptoms in order to estimate the amount of [[dosha]].

Mobility (chalatva) is a property of [[vata]][[dosha]]. If this property is lost in a subject, that can be inferred as an abnormal reduction in [[vata]][[dosha]]. This type of properties can be assessed in patients in the form of signs and symptoms in order to estimate the amount of [[dosha]].

The physical properties are measurable, whose value describes a state of a physical system. These are listed as below<ref>Available from https://en.wikipedia.org/wiki/Physical_property accessed on 10/07/2020</ref>.  The probable correspondent guna is given as below. However, it shall be clear that the guna concept of Ayurveda shows some biological effect after interaction with human biology. Whereas the physical properties of a substance are observed in vitro and not necessarily show the same biological effect as of guna. More research is needed to study the degree of co-relation of the same.  

The physical properties are measurable, whose value describes a state of a physical system. These are listed as below<ref>Available from https://en.wikipedia.org/wiki/Physical_property accessed on 10/07/2020</ref>.  The probable correspondent guna is given as below. However, it shall be clear that the guna concept of Ayurveda shows some biological effect after interaction with human biology. Whereas the physical properties of a substance are observed in vitro and not necessarily show the same biological effect as of guna. More research is needed to study the degree of co-relation of the same.  

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==Current researches==

==Current researches==

Some experimental research studies have been conducted to refine the objective parameters used for assessing unctuousness-dryness (snigdha-ruksha) and cold-hot (sheeta-ushna) properties by employing suitable pharmacological models. Absolute evaluation of one guna is not possible in a living body since there are infinite factors related to each and every biological event. Metabolic study (dipana pachana experiment), intestinal secretion and motility test, and swimming stress test (swimming induced hypothermia) have been employed to assess the effects of various drugs having unctuous-dry, cold-hot properties. Drugs with cold and unctuous properties have shown to increase in body weight in metabolic experiments compared to drugs with hot and dry properties.  Drugs with unctuous property alleviated stress-induced hypothermia, drugs with dry property aggravated it.<ref>Supriya. S. Balerao A comprehensive study of gunas and evolution of some ojective parameters in the context of snigdha and rukshagunas Thesis, IPGT&RA, Gujarat Ayurved University, Jamnagar,1998</ref> <ref>Santosh Mane Evolution and evaluation of some objective parameters for ushna and sitagunas based on panchabhoutik theory and experiments. Thesis,IPGT&RA, Gujarat Ayurved University, Jamnagar,2008</ref>

Some experimental research studies have been conducted to refine the objective parameters used for assessing unctuousness-dryness (snigdha-ruksha) and cold-hot (sheeta-ushna) properties by employing suitable pharmacological models. Absolute evaluation of one guna is not possible in a living body since there are infinite factors related to each and every biological event. Metabolic study (dipana pachana experiment), intestinal secretion and motility test, and swimming stress test (swimming induced hypothermia) have been employed to assess the effects of various drugs having unctuous-dry, cold-hot properties. Drugs with cold and unctuous properties have shown to increase in body weight in metabolic experiments compared to drugs with hot and dry properties.  Drugs with unctuous property alleviated stress-induced hypothermia, drugs with dry property aggravated it.<ref>Supriya. S. Balerao A comprehensive study of gunas and evolution of some ojective parameters in the context of snigdha and ruksha gunas Thesis, IPGT&RA, Gujarat Ayurved University, Jamnagar,1998</ref> <ref>Santosh Mane Evolution and evaluation of some objective parameters for ushna and shita gunas based on panchabhoutik theory and experiments. Thesis,IPGT&RA, Gujarat Ayurved University, Jamnagar,2008</ref>

In another clinical research, the administration of drugs with dry property showed significant reduction in serum cholesterol levels in patients of hyperlipidemia. Hyperlipidemia is considered as elevated unctuousness in body.<ref>Mishra S, Dwivedi R R, Ravishankar B. Conceptual and applied study of Snigdha and RuksaGuna with special reference to Rasa-raktagata Sneha (hyperlipidemia). AYU [serial online] 2011 [cited 2020 Jul 8];32:200-6. Available from: http://www.ayujournal.org/text.asp?2011/32/2/200/92586</ref>

In another clinical research, the administration of drugs with dry property showed significant reduction in serum cholesterol levels in patients of hyperlipidemia. Hyperlipidemia is considered as elevated unctuousness in body.<ref>Mishra S, Dwivedi R R, Ravishankar B. Conceptual and applied study of Snigdha and RuksaGuna with special reference to Rasa-raktagata Sneha (hyperlipidemia). AYU [serial online] 2011 [cited 2020 Jul 8];32:200-6. Available from: http://www.ayujournal.org/text.asp?2011/32/2/200/92586</ref>