Changes

==Current researches ==

==Current researches ==

• Replacement of red hematopoietic bone marrow with yellow adipocyte-rich marrow is a conserved physiological process among mammals. Several important molecular characteristics of bone marrow adipose tissue (BMAT) are distinct from the classical depots of white and brown fat tissue. This depot of fat has recently emerged as an active part of the bone marrow niche that exerts paracrine and endocrine functions thereby controlling osteogenesis and hematopoiesis.  

• Replacement of red hematopoietic bone marrow with yellow adipocyte-rich marrow is a conserved physiological process among mammals. Several important molecular characteristics of bone marrow adipose tissue (BMAT) are distinct from the classical depots of white and brown fat tissue. This depot of fat has recently emerged as an active part of the bone marrow niche that exerts paracrine and endocrine functions thereby controlling osteogenesis and hematopoiesis.<ref>Ambrosi TH, Schulz TJ ,The emerging role of bone marrow adipose tissue in bone health and dysfunction,J Mol Med (Berl). 2017 Dec;95(12)1291-1301. doi 10.1007/s00109-017-1604-7. Epub 2017 Nov 3</ref>

• Bone marrow-derived mesenchymal stem cells (BM-MSCs) have the potential of differentiation and they secrete anti-inflammatory cytokines and growth factors which make them appropriate for cell therapy. A study conducted to evaluate the healing effect of BM-MSCs transplantation on germinal cells showed that the transplanted BM-MSCs could successfully induce spermatogenesis in seminiferous tubules of azoospermic hamster. Therefore, BM-MSCs can be an attractive candidate in cell transplantation of azoospermia.  

• Bone marrow-derived mesenchymal stem cells (BM-MSCs) have the potential of differentiation and they secrete anti-inflammatory cytokines and growth factors which make them appropriate for cell therapy. A study conducted to evaluate the healing effect of BM-MSCs transplantation on germinal cells showed that the transplanted BM-MSCs could successfully induce spermatogenesis in seminiferous tubules of azoospermic hamster. Therefore, BM-MSCs can be an attractive candidate in cell transplantation of azoospermia.<ref>Tamadon A et al, Induction of Spermatogenesis by Bone Marrow-derived Mesenchymal Stem Cells in Busulfan-induced Azoospermia in Hamster,Int J Stem Cells. 2015 Nov;8(2)134-45. doi 10.15283/ijsc.2015.8.2.134</ref>

• In a clinical study, it is observed that majja basti (therapeutic enema with bone marrow) along with oral intake of asthi shrinkhala(Cissus quadrangularis) shows encouraging results in the management of osteoporosis (asthi-majjakshaya) and it also improves the general health of the patients.   

• In a clinical study, it is observed that majja basti (therapeutic enema with bone marrow) along with oral intake of asthi shrinkhala(Cissus quadrangularis) shows encouraging results in the management of osteoporosis (asthi-majjakshaya) and it also improves the general health of the patients.<ref>Ajay K. Gupta et al, Effect of Majja Basti (therapeutic enema) and Asthi Shrinkhala (Cissus quadrangularis) in the management ofOsteoporosis (Asthi-Majjakshaya),AYU , Jan-Mar 2012 , Vol 33 ,Issue 1,pg.110-113</ref>  

'''Further scope of research'''  

'''Further scope of research'''  

===List of theses done===

===List of theses done===

1.Ajay K Gupta (2010)  Effect of majja basti&asthi shrinkhala in the management of osteoporosis w.s.r. to asthi-majja kshaya-A clinical study, department of panchakarma, IPGT &RA, Jamnagar.

1. Ajay K Gupta (2010): Effect of majja basti&asthi shrinkhala in the management of osteoporosis w.s.r. to asthi-majja kshaya-A clinical study, department of panchakarma, IPGT &RA, Jamnagar.

2.Saurabh R Bhuva(2012)  A Comparative Study of Matra Basti and Brimhana Snehana by Asthishrinkhala Ghrita in the management of Asthi-Majja Kshaya w.s.r. to Osteopenia / Osteoporosis, department of panchakarma, IPGT &RA, Jamnagar.

2. Saurabh R Bhuva(2012): A Comparative Study of Matra Basti and Brimhana Snehana by Asthishrinkhala Ghrita in the management of Asthi-Majja Kshaya w.s.r. to Osteopenia / Osteoporosis, department of panchakarma, IPGT &RA, Jamnagar.

==More information ==

==More information ==