Changes

'''''Katukrohini''''' or ''kutaki'' (Picrorrhiza kurroa): ''Kutaki'' has ''tikta rasa, katu vipaka'' and ''sheeta veerya''. It possesses a strong hepatoprotective properties due to phytochemical picroliv and also have a potent antioxidant properties<ref> Phytochemical and Pharmacological Standardisation of Polyherbal Tablets For Hepatoprotective Activity Against Carbon Tetrachloride  </ref>.  It is found to be effective against CCl4 induced hepatic damage in rats, by reversal of increased serum level of SGOT, SGPT, ALP, Cholesterol, Bilirubin and decreases level of total protein which occurs during hepatotoxicit<ref> Induced HepatotoxicityVilas A. Arsul*, R. O. Ganjiwale, P. G. Yeole International Journal of Pharmaceutical Sciences and Drug Research 2010; 2(4): 265-268 </ref>.   

'''''Katukrohini''''' or ''kutaki'' (Picrorrhiza kurroa): ''Kutaki'' has ''tikta rasa, katu vipaka'' and ''sheeta veerya''. It possesses a strong hepatoprotective properties due to phytochemical picroliv and also have a potent antioxidant properties<ref> Phytochemical and Pharmacological Standardisation of Polyherbal Tablets For Hepatoprotective Activity Against Carbon Tetrachloride  </ref>.  It is found to be effective against CCl4 induced hepatic damage in rats, by reversal of increased serum level of SGOT, SGPT, ALP, Cholesterol, Bilirubin and decreases level of total protein which occurs during hepatotoxicit<ref> Induced HepatotoxicityVilas A. Arsul*, R. O. Ganjiwale, P. G. Yeole International Journal of Pharmaceutical Sciences and Drug Research 2010; 2(4): 265-268 </ref>.   

'''''Bruhati''''' (Solanum indicum): ''Bruhati'' has ''katu tikta rasa, katu vipaka'' and ''ushna veerya''. Solanum indicum Linn. fruits have laxative and cardiotonic action<ref> Evaluation of laxative and cardiotonic activity of solanum indicum linn. Fruits Prashanta Kumar Deb Journal of Pharmacy and Phytotheraputics J Pharm Phytother 2013, 1:3, 11 – 14 </ref>.  

'''''Brihati''''' (Solanum indicum): ''Brihati'' has ''katu tikta rasa, katu vipaka'' and ''ushna veerya''. Solanum indicum Linn. fruits have laxative and cardiotonic action<ref> Evaluation of laxative and cardiotonic activity of solanum indicum linn. Fruits Prashanta Kumar Deb Journal of Pharmacy and Phytotheraputics J Pharm Phytother 2013, 1:3, 11 – 14 </ref>.  

'''''Ativisha''''' (Aconitum hetrophyllum): has ''tikta katu rasa, katu vipaka'' and ''ushna veerya''. It is ''laghu'' and ''ruksha'' and hence is used in ''santarpaniya vyadhis''. Research showed significant reduction in total cholesterol, TG, apolipoprotein B and increase HDL cholesterol and apolipoprotein A in serum samples and HMG CO A properties in liver samples. Properties of LCAT had increased and also there was increased fecal fat excretion. The mechanism explained for hypolipidemic properties was due to inhibition of HMG COA reductase properties and decrease fat absorption from intestine<ref> Arun Koorapally subash, Anu Augustine, Hypo lipidemic effect of methnol fraction of Aconitum heterophyllum wall ex Royle and the mechanism of action in diet induced obese rats. J.Adv.Pharm. Tech. Res, vol.8, (issue 4):oct-dec ,(2012). </ref>.  

'''''Ativisha''''' (Aconitum hetrophyllum): has ''tikta katu rasa, katu vipaka'' and ''ushna veerya''. It is ''laghu'' and ''ruksha'' and hence is used in ''santarpaniya vyadhis''. Research showed significant reduction in total cholesterol, TG, apolipoprotein B and increase HDL cholesterol and apolipoprotein A in serum samples and HMG CO A properties in liver samples. Properties of LCAT had increased and also there was increased fecal fat excretion. The mechanism explained for hypolipidemic properties was due to inhibition of HMG COA reductase properties and decrease fat absorption from intestine<ref> Arun Koorapally subash, Anu Augustine, Hypo lipidemic effect of methnol fraction of Aconitum heterophyllum wall ex Royle and the mechanism of action in diet induced obese rats. J.Adv.Pharm. Tech. Res, vol.8, (issue 4):oct-dec ,(2012). </ref>.