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→4. Rushyajivha kushtha
It is predominated by ''kapha dosha''. The ''sthira, snigdha guna'' brings about ''sthirata'' and ''snigdhata'' to the ''kushtha''. Therefore the lesion is granulomatous in presentation. The early and indeterminate leprosy especially lepromatous leprosy is a skin condition consisting of pale macules. It results from failure of Th1 cell activation which is necessary to eradicate the mycobacteria. In Lepromatous Leprosy Th2 response is turned on and because of reciprocal inhibition the cell mediated response is depressed.
It is predominated by ''kapha dosha''. The ''sthira, snigdha guna'' brings about ''sthirata'' and ''snigdhata'' to the ''kushtha''. Therefore the lesion is granulomatous in presentation. The early and indeterminate leprosy especially lepromatous leprosy is a skin condition consisting of pale macules. It results from failure of Th1 cell activation which is necessary to eradicate the mycobacteria. In Lepromatous Leprosy Th2 response is turned on and because of reciprocal inhibition the cell mediated response is depressed.
===== 4. Rushyajivha kushtha =====
===== 4. ''Rishyajivha kushtha'' =====
It is dominated by vāta and pitta dōṣa. Vāta dōṣa brings roughness, pain whereas pitta is responsible for the discolouration, burning sensation whereas both the dōṣa are responsible for ashugati and samuthan.
It is dominated by ''vata'' and ''pitta dosha''. ''Vata dosha'' brings roughness, pain whereas ''pitta'' is responsible for the discoloration, burning sensation whereas both the ''dosha'' are responsible for ''ashugati'' and ''samuthana''.
Thus inflammatory and degenerative changes dominate the condition. Pathogenesis involving infective origin or allergic origin may be included. Diseases such as Lyme disease may be included. Expanding redness known as erythema migrans begins at the site of bite after a period of one week. There is no much itching i.e. alpa kandu but the rash is red and warm but generally painless. Classically the innermost portion remain darker red and becomes indurated (is thicker and firmer).
Thus inflammatory and degenerative changes dominate the condition. Pathogenesis involving infective origin or allergic origin may be included. Diseases such as Lyme disease may be included. Expanding redness known as erythema migrans begins at the site of bite after a period of one week. There is no much itching i.e. ''alpa kandu'' but the rash is red and warm but generally painless. Classically the innermost portion remain darker red and becomes indurated (is thicker and firmer).
===== 5. Pundarika kushtha =====
===== 5. Pundarika kushtha =====