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<div style='text-align:justify;'>
 
<div style='text-align:justify;'>
 
It may act through vascular route(myo-enteric venous plexus),nervous route(specifically act on apana&samanavata,hence ENS involved).
 
It may act through vascular route(myo-enteric venous plexus),nervous route(specifically act on apana&samanavata,hence ENS involved).
[[File:Nervous system.jpg|center]]
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[[File:Nervous systems.jpg|center]]
 
There may be possible correlation -
 
There may be possible correlation -
* It modulates endocrine functions [[File:Endocrine.jpg]] (myoentericplexus—ANS—Brain—Pituitary—Adrenal ovarian/testicular axis).
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* It modulates endocrine functions (myoentericplexus—ANS—Brain—Pituitary—Adrenal ovarian/testicular axis).
 
* It maycauses pressure variation of intestinal mucosa, which may induce difference in intestinal intra- cellular and extra -cellular fluid.
 
* It maycauses pressure variation of intestinal mucosa, which may induce difference in intestinal intra- cellular and extra -cellular fluid.
 
* It acts by a curious bio feedback mechanism yet to be identified.
 
* It acts by a curious bio feedback mechanism yet to be identified.