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A 45 year old female with multiple joint pain associated with swelling, morning stiffness, movement restricted and loss of appetite. She was diagnosed with amavata. Treatment includes [[deepana]]-[[pachana]] with amapachanavati for 1 week. It was followed by internal administration of cow’s ghee in escalating dose pattern for 5 days. Fomentation was done for the next 3 days which was followed by therapeutic purgation ([[virechana]]) with Trivritaavaleha (100gm) and castor oil (20ml). After completion of [[virechana]] and diet protocol (samsarjana krama), the 40% reduction in pain and stiffness of joints. RA factor was reduced from 94 IU/ml to 50 IU/ml after [[virechana]]. The patient was put on specific diet pattern after [[virechana]]. After 3 months of treatment, there was significant reduction in all signs and symptoms of amavata. IgE was reduced from 680 kU/L to 53.7 kU/L.<ref name=Gupta>Gupta SK, Thakar AB, Dudhamal TS, Nema A. Management of Amavata(rheumatoid arthritis) with diet and Virechanakarma. Ayu 2015;36:413-5. </ref>
A 45 year old female with multiple joint pain associated with swelling, morning stiffness, movement restricted and loss of appetite. She was diagnosed with amavata. Treatment includes [[deepana]]-[[pachana]] with amapachanavati for 1 week. It was followed by internal administration of cow’s ghee in escalating dose pattern for 5 days. Fomentation was done for the next 3 days which was followed by therapeutic purgation ([[virechana]]) with Trivritaavaleha (100gm) and castor oil (20ml). After completion of [[virechana]] and diet protocol (samsarjana krama), the 40% reduction in pain and stiffness of joints. RA factor was reduced from 94 IU/ml to 50 IU/ml after [[virechana]]. The patient was put on specific diet pattern after [[virechana]]. After 3 months of treatment, there was significant reduction in all signs and symptoms of amavata. IgE was reduced from 680 kU/L to 53.7 kU/L.<ref name=Gupta>Gupta SK, Thakar AB, Dudhamal TS, Nema A. Management of Amavata(rheumatoid arthritis) with diet and Virechanakarma. Ayu 2015;36:413-5. </ref>
==Research updates==
===Research updates===
A double dummy randomized pilot trail was conducted to compare classic [[Ayurveda]], methotrexate (MTX), and their combination in rheumatoid arthritis (RA) for 36 weeks. Forty-three seropositive RA patients were diagnosed on criteria by American College of Rheumatology (ACR) criteria. The treatment groups included MTX plus Ayurvedic placebo (n = 14), Ayurveda plus MTX placebo (n = 12), or Ayurveda plus MTX (n = 17). It was observed that all three treatments were approximately equivalent in efficacy. Adverse events were numerically fewer in the [[Ayurveda]]-only group. <ref>Furst, Daniel E. MD*; Venkatraman, Manorama M. PhD†; McGann, Mary MPH, MSW**; Manohar, P. Ram MD (Ayurveda)‡; Booth-LaForce, Cathryn PhD†; Sarin, Reshmi MD (Ayurveda)‡; Sekar, P.G. MBBS**✠; Raveendran, K.G. BAM&S‡; Mahapatra, Anita MD§; Gopinath, Jidesh BS‡; Kumar, P.R. Krishna BAM&S‡ Double-Blind, Randomized, Controlled, Pilot Study Comparing Classic Ayurvedic Medicine, Methotrexate, and Their Combination in Rheumatoid Arthritis, Journal of Clinical Rheumatology: June 2011 - Volume 17 - Issue 4 - p 185-192 doi: 10.1097/RHU.0b013e31821c0310</ref>
A double dummy randomized pilot trail was conducted to compare classic [[Ayurveda]], methotrexate (MTX), and their combination in rheumatoid arthritis (RA) for 36 weeks. Forty-three seropositive RA patients were diagnosed on criteria by American College of Rheumatology (ACR) criteria. The treatment groups included MTX plus Ayurvedic placebo (n = 14), Ayurveda plus MTX placebo (n = 12), or Ayurveda plus MTX (n = 17). It was observed that all three treatments were approximately equivalent in efficacy. Adverse events were numerically fewer in the [[Ayurveda]]-only group. <ref>Furst, Daniel E. MD*; Venkatraman, Manorama M. PhD†; McGann, Mary MPH, MSW**; Manohar, P. Ram MD (Ayurveda)‡; Booth-LaForce, Cathryn PhD†; Sarin, Reshmi MD (Ayurveda)‡; Sekar, P.G. MBBS**✠; Raveendran, K.G. BAM&S‡; Mahapatra, Anita MD§; Gopinath, Jidesh BS‡; Kumar, P.R. Krishna BAM&S‡ Double-Blind, Randomized, Controlled, Pilot Study Comparing Classic Ayurvedic Medicine, Methotrexate, and Their Combination in Rheumatoid Arthritis, Journal of Clinical Rheumatology: June 2011 - Volume 17 - Issue 4 - p 185-192 doi: 10.1097/RHU.0b013e31821c0310</ref>