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Panchamooladikaalabasti is reported to be effective in reducing the symptoms of rheumatoid arthritis (amavata) especially  pain, stiffness, swelling and tenderness in the joints. It is also found effective in reducing the generalized symptoms like heaviness of body, fatigue, feverishness and anorexia. Basti acts over the prime seat of [[vata dosha]] i.e. large intestine (pakvashaya) and controls it. The alkali present in the ksharabasti improves digestion and removes the accumulated toxins (ama).<ref name=BariaR>Baria R, Joshi N, Pandya D. Clinical efficacy of Panchamuladi Kaala Basti (enema) in the management of Amavata (Rheumatoid Arthritis). Ayu. 2011 Jan;32(1):90-4. doi: 10.4103/0974-8520.85737. PMID: 22131764; PMCID: PMC3215425.</ref>  
 
Panchamooladikaalabasti is reported to be effective in reducing the symptoms of rheumatoid arthritis (amavata) especially  pain, stiffness, swelling and tenderness in the joints. It is also found effective in reducing the generalized symptoms like heaviness of body, fatigue, feverishness and anorexia. Basti acts over the prime seat of [[vata dosha]] i.e. large intestine (pakvashaya) and controls it. The alkali present in the ksharabasti improves digestion and removes the accumulated toxins (ama).<ref name=BariaR>Baria R, Joshi N, Pandya D. Clinical efficacy of Panchamuladi Kaala Basti (enema) in the management of Amavata (Rheumatoid Arthritis). Ayu. 2011 Jan;32(1):90-4. doi: 10.4103/0974-8520.85737. PMID: 22131764; PMCID: PMC3215425.</ref>  
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Unctuous enema in minimum dose (matrabasti) is found effective in 12 cases of anovulation. Ovulation occurred in the maximum number of participants (63.64%) and increased follicular size is also reported after matrabasti. Basti shows its action on Enteric Nervous System (ENS). The endogenous opioids especially beta endorphins may get stimulated. This may affect the GnRH secretion and there by regularize hypothalamo pituitary ovarian (HPO) axis. HPO axis regulates the ovarian cycle and ovulation. By the action over ENS, basti may also stimulate CNS and thereby stimulates pituitary. This results in the secretion of FSH and LH which plays an important role in ovulation.  More studies are needed to study the effect of basti on specific pathways.<ref>Donga KR, Donga SB, Dei LP. Role of Nasya and Matra Basti with Narayana Taila on anovulatory factor. Ayu. 2013 Jan;34(1):81-5. doi: 10.4103/0974-8520.115453. PMID: 24049410; PMCID: PMC3764886.</ref>
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Unctuous enema in minimum dose (matrabasti) is found effective in 12 cases of anovulation. Ovulation occurred in the maximum number of participants (63.64%) and increased follicular size is also reported after matrabasti. Basti shows its action on Enteric Nervous System (ENS). The endogenous opioids especially beta endorphins may get stimulated. This may affect the GnRH secretion and there by regularize hypothalamo pituitary ovarian (HPO) axis. HPO axis regulates the ovarian cycle and ovulation. By the action over ENS, basti may also stimulate CNS and thereby stimulates pituitary. This results in the secretion of FSH and LH which plays an important role in ovulation.<ref>Donga KR, Donga SB, Dei LP. Role of Nasya and Matra Basti with Narayana Taila on anovulatory factor. Ayu. 2013 Jan;34(1):81-5. doi: 10.4103/0974-8520.115453. PMID: 24049410; PMCID: PMC3764886.</ref> More studies are needed to study the effect of basti on specific pathways.
    
==List of theses done==
 
==List of theses done==
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