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If the genes in the chromosomes (beejabhaga) which are responsible for the formation of a particular organ get vitiated or mutated (vikruta), this will result in the improper formation of the respective organ.[Cha. Sa. [[Sharira Sthana]] 3/17]
 
If the genes in the chromosomes (beejabhaga) which are responsible for the formation of a particular organ get vitiated or mutated (vikruta), this will result in the improper formation of the respective organ.[Cha. Sa. [[Sharira Sthana]] 3/17]
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When a woman gets conceived in a state that her ovum (shonita) and uterus (garbhashaya) were not completely vitiated but simply afflicted by the circulating aggravated [[doshas ]]because of her improper regimens, one or many of the organs of the fetus which derive from the maternal source get deformed. This is the explanation given for the congenital deformities in organs of maternal origin. [Cha. Sa. [[Sharira Sthana]] 4/30]
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When a woman gets conceived in a state that her ovum (shonita) and uterus (garbhashaya) were not completely vitiated but simply afflicted by the circulating aggravated [[doshas]] because of her improper regimens, one or many of the organs of the fetus which derive from the maternal source get deformed. This is the explanation given for the congenital deformities in organs of maternal origin. [Cha. Sa. [[Sharira Sthana]] 4/30]
    
The yoni vyapad namely “shandi” is an example for the abnormalities in gametes (beeja dushti) leading to the deformity of anatomical structures (ashaya) in fetus due to affliction of [[vata]] leading to the female progeny with underdeveloped primary and secondary sexual characters [Cha. Sa. [[Chikitsa Sthana]] 30/34-35] which is generally correlated by many scholars with the chromosomal disorder known as “turner syndrome”.
 
The yoni vyapad namely “shandi” is an example for the abnormalities in gametes (beeja dushti) leading to the deformity of anatomical structures (ashaya) in fetus due to affliction of [[vata]] leading to the female progeny with underdeveloped primary and secondary sexual characters [Cha. Sa. [[Chikitsa Sthana]] 30/34-35] which is generally correlated by many scholars with the chromosomal disorder known as “turner syndrome”.
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