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== Functions ==
== Functions ==
The important function of asthi dhatu is providing structure and support to the body.It also nourishes the successor bone marrow tissue (majja dhatu).[Su. Sa. Sutra Sthana 15/5]
In addition, contemporary physiology states that bone tissue carries out following functions too.
The important function of asthi dhatu is providing structure and support to the body. It also nourishes the successor bone marrow tissue ([[majja dhatu]]).[Su. Sa. Sutra Sthana 15/5]
In addition, contemporary physiology states that bone tissue carries out the following functions too.
Mechanical:
Mechanical:
• Protection : It protect internal organs
• Protection : It protect internal organs
• Movement: facilitate movement
• Movement: facilitate movement
• Hearing: Facilitate hearing through sound transduction
• Hearing: Facilitate hearing through sound transduction
Synthesis:
Synthesis:
The cancellous part of bone contains bone marrow. It produces blood cells including red blood cells, platelets and white blood cells. This process is called as hematopoiesis.
The cancellous part of the bone contains bone marrow. It produces blood cells including red blood cells, platelets and white blood cells. This process is called as hematopoiesis.
Metabolism:
Metabolism:
The bone tissue regulatesacid-base balance, store calcium and fat cells. It acts as endocrine organ by controlling the phosphate metabolism. It releasesfibroblast growth factor – 23 (FGF-23), which acts on kidneys to reduce phosphate reabsorption. The bone cells also release a hormone called osteocalcin. This contributes to the regulation of blood sugar (glucose) and fat deposition. Osteocalcin increases both the insulin secretion and sensitivity, in addition to boosting the number of insulin-producing cells and reducing stores of fat.
The bone tissue regulates acid-base balance, stores calcium, and fat cells. It acts as an endocrine organ by controlling the phosphate metabolism. It release fibroblast growth factor – 23 (FGF-23), which acts on kidneys to reduce phosphate reabsorption. The bone cells also release a hormone called osteocalcin. This contributes to the regulation of blood sugar (glucose) and fat deposition. Osteocalcin increases both insulin secretion and sensitivity, in addition to boosting the number of insulin-producing cells and reducing stores of fat.
==Importance in diagnosis==
==Importance in diagnosis==
===Causes of vitiation===
===Causes of vitiation===