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As the name suggests, it is a bulky tissue and denotes the status of nutrition. Due to its solid-state, it provides proper size, shape and dimension to the body.   

As the name suggests, it is a bulky tissue and denotes the status of nutrition. Due to its solid-state, it provides proper size, shape and dimension to the body.   

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== Etymology and derivation ==

=== Etymology and derivation ===

The word is derived from Sanskrit root called “Mans” meaning flesh or meat.<ref> Monier Williams (1899), “mamsa”, in A Sanskrit–English Dictionary, new edition, Oxford: At the Clarendon Press, OCLC 458052227, page 805</ref>  Mamsa dhatu is the component which enhances body mass, covers body parts, takes part in flexion and extension movements of joints with muscles and tendons attached to it.<ref>Jha Srujan. Amarkosha online application</ref>

The word is derived from Sanskrit root called “Mans” meaning flesh or meat.<ref> Monier Williams (1899), “mamsa”, in A Sanskrit–English Dictionary, new edition, Oxford: At the Clarendon Press, OCLC 458052227, page 805</ref>  Mamsa dhatu is the component which enhances body mass, covers body parts, takes part in flexion and extension movements of joints with muscles and tendons attached to it.<ref>Jha Srujan. Amarkosha online application</ref>

==Synonyms ==

=== Synonyms ===

'''Pishita''': Found to be separated in single fibers (Vibhakta in Peshi svaroopa)

'''Pishita''': Found to be separated in single fibers (Vibhakta in Peshi svaroopa)

'''Medaskrut''' : Involved in origin and development of next [[dhatu]] – [[Medas]]

'''Medaskrut''' : Involved in origin and development of next [[dhatu]] – [[Medas]]

== Meanings in different contexts ==

=== Meanings in different contexts ===

* In physiology, the word denotes structural and functional components mainly of muscle tissue.

* In physiology, the word denotes structural and functional components mainly of muscle tissue.

* A dietary preparation of "mamsarasa – Veshavara"(meat soup) is best for nourishing the body.[Cha. Sa. [[Sutra Sthana]] 25/40]

* A dietary preparation of "mamsarasa – Veshavara"(meat soup) is best for nourishing the body.[Cha. Sa. [[Sutra Sthana]] 25/40]

== Panchabhautika constitution and properties ==

== Fundamnetal constitution (panchabhautika sanghatana) and properties ==

*[[Vayu]], [[jala]] and [[agni mahabhuta]] play major role in the formation of "mamsa". [Cha. Sa. [[Chikitsa  Sthana]] 15/29] After formation, it has predominance of [[prithvi mahabhuta]].

*[[Vayu]], [[jala]] and [[agni mahabhuta]] play major role in the formation of "mamsa". [Cha. Sa. [[Chikitsa  Sthana]] 15/29] After formation, it has predominance of [[prithvi mahabhuta]].

The mamsa dhatu is formed on 3rd day from the nutrient fluid (ahara rasa). [Cha.Sa. [[Chikitsa Sthana]] 15/20-21] However, Sushruta opines that the mamsa dhatu is formed in a time span of 6030 kala (ten days). [Su. Sa. Sutra Sthana 14/14]  

The mamsa dhatu is formed on 3rd day from the nutrient fluid (ahara rasa). [Cha.Sa. [[Chikitsa Sthana]] 15/20-21] However, Sushruta opines that the mamsa dhatu is formed in a time span of 6030 kala (ten days). [Su. Sa. Sutra Sthana 14/14]  

== Characteristics of best quality or essence (mamsa Sara): ==  

== Characteristics of best quality or essence (mamsa Sara) ==  

The persons having essence of mamsa dhatu have their temples (shankha), forehead (lalata), nape (krikatika), eyes (akshi), cheek (ganda), jaws (hanu), neck (griva), shoulder (skandha), abdomen (udara), axillae (kaksha), chest (vaksha), hands (pani), feet (pada)and joints (sandhi) well developed with firm, heavy and good looking muscles. This essence indicates forbearance, restraint, and lack of greed, wealth, knowledge, happiness, simplicity, health, strength and longevity.[Cha.Sa. [[Vimana Sthana]] 8/105]

The persons having essence of mamsa dhatu have their temples (shankha), forehead (lalata), nape (krikatika), eyes (akshi), cheek (ganda), jaws (hanu), neck (griva), shoulder (skandha), abdomen (udara), axillae (kaksha), chest (vaksha), hands (pani), feet (pada)and joints (sandhi) well developed with firm, heavy and good looking muscles. This essence indicates forbearance, restraint, and lack of greed, wealth, knowledge, happiness, simplicity, health, strength and longevity.[Cha.Sa. [[Vimana Sthana]] 8/105]

Any vitiation or direct injury to the channels of transportation and transformation of mamsa dhatu (mamsavaha strotas) can lead to death. [Su.Sha.Sharir Sthana 9/12]

Any vitiation or direct injury to the channels of transportation and transformation of mamsa dhatu (mamsavaha strotas) can lead to death. [Su.Sha.Sharir Sthana 9/12]

===Causes of vitiation===

=== Causes of vitiation ===

The following are causative factors for the vitiation of channels for transport and transformation of mamsa dhatu (mamsavaha srotasa). [Cha. Sa. [[Vimana Sthana]] 5/15]

The following are causative factors for the vitiation of channels for transport and transformation of mamsa dhatu (mamsavaha srotasa). [Cha. Sa. [[Vimana Sthana]] 5/15]

* Identification of genetic variations at base-pair resolution throughout the human genome which targets the proportion of DNA that codes proteins for capturing and sequencing.  

* Identification of genetic variations at base-pair resolution throughout the human genome which targets the proportion of DNA that codes proteins for capturing and sequencing.  

=== Patholoigcal conditions ===

=== Pathological conditions ===

==== Hemorrhagic changes in muscles ====

==== Hemorrhagic changes in muscles ====

   

   

A well-known but so far poorly understood condition is the focal red changes in muscle, often referred to as haemorrhages. Such changes are characterized by muscle necrosis, haemorrhages, and acute inflammation. In situ hybridization(ISH) studies on IgM showed few to moderate amounts of B-cells in red focal changes. Trends in the RT-qPCR showed up-regulation of genes related to innate immunity in the red changes, whereas genes related to adaptive immunity were upregulated in the melanized changes. An important result was the significant down-regulation of the anti-inflammatory cytokine IL10 in all red changes.<ref>HåvardBjørgen et al,Immunopathological characterization of red focal changes in Atlantic salmon (Salmo salar) white muscle, Veterinary Immunology and Immunopathology Volume 222, April 2020, 110035,https://doi.org/10.1016/j.vetimm.2020.110035</ref>

A well-known but so far poorly understood condition is the focal red changes in muscle, often referred to as haemorrhages. Such changes are characterized by muscle necrosis, haemorrhages, and acute inflammation. In situ hybridization(ISH) studies on IgM showed few to moderate amounts of B-cells in red focal changes. Trends in the RT-qPCR showed up-regulation of genes related to innate immunity in the red changes, whereas genes related to adaptive immunity were upregulated in the melanized changes. An important result was the significant down-regulation of the anti-inflammatory cytokine IL10 in all red changes.<ref>Havard Bjorgen et al,Immunopathological characterization of red focal changes in Atlantic salmon (Salmo salar) white muscle, Veterinary Immunology and Immunopathology Volume 222, April 2020, 110035,https://doi.org/10.1016/j.vetimm.2020.110035</ref>

   

   

===List of theses ===

===List of theses ===

1.Pritesh A Dave(2007): A pilot study on sports medicine in ayurveda w.s.r. To sarira bala vrddhi, Department of Basic principles, IPGT &RA, Jamnagar

 

1. Pritesh A Dave(2007): A pilot study on sports medicine in ayurveda w.s.r. To sarira bala vrddhi, Department of Basic principles, I P G T & R A , Jamnagar

== More information ==

== More information ==