Changes

The most common inherited bleeding disorders are:

The most common inherited bleeding disorders are:

*hemophilia A and B: caused by a deficiency or lack of certain blood clotting proteins, called factors. This disorder causes heavy or unusual bleeding

*'''Hemophilia A and B''': caused by a deficiency or lack of certain blood clotting proteins, called factors. This disorder causes heavy or unusual bleeding

*factor II, V, VII, X, XII deficiency: relate to blood clotting problems or abnormal bleeding problems

*'''Factor II, V, VII, X, XII deficiency''': relate to blood clotting problems or abnormal bleeding problems

*von Willebrand’s disease: the most common inherited bleeding disorder; caused by a deficiency of von Willebrand factor, which helps blood platelets clump together and stick to a blood vessel wall  

*'''von Willebrand’s Disease''': the most common inherited bleeding disorder; caused by a deficiency of von Willebrand factor, which helps blood platelets clump together and stick to a blood vessel wall.

Certain diseases or medical conditions can also cause a deficiency of one or more blood clotting factors. The most common causes of acquired bleeding disorders are end-stage liver disease or vitamin K deficiency. According to the American Association of Clinical Chemistry (AACC), this is because most blood clotting factors are produced in the liver, and certain clotting factors are vitamin k dependent (AACC, 2011).

Certain diseases or medical conditions can also cause a deficiency of one or more blood clotting factors. The most common causes of acquired bleeding disorders are end-stage liver disease or vitamin K deficiency. According to the American Association of Clinical Chemistry (AACC), this is because most blood clotting factors are produced in the liver, and certain clotting factors are vitamin k dependent (AACC, 2011).