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→Prameha classified according to physique
#''Sthula pramehi'' refers to obese diabetic patients and corresponds to individuals with Type 2 diabetes, and
#''Sthula pramehi'' refers to obese diabetic patients and corresponds to individuals with Type 2 diabetes, and
#''Krisha pramehi'' refers to asthenic diabetic patients and corresponds to ''krisha pramehi'' corresponds to patients with Type-I diabetes.
#''Krisha pramehi'' refers to asthenic diabetic patients and corresponds to ''krisha pramehi'' corresponds to patients with Type-I diabetes.<ref> Kajaria Divya, Chandola H.M. Dislipidemia Cause or Consequence of Diabetes- Reanalyzing the pathogenesis with the vision of Ayurveda. Journal of Diabetes and Health, Photon. 2014. </ref>
Research shows that sedentary lifestyle, coupled with an excessive intake of sugar-rich substances lead to a build up of toxins that could be equated to ''ama'' (or toxins resulting from improperly digested food and metabolic products). This ''ama'' then leads to the formation of ''meda'' (fat). When this resultant ''meda'' is also coupled with vitiated ''doshas'' (primarily, ''kapha'' and ''vata''), and ''agni'' (the digestive processes), it provides for a conducive ground for the causation of ''prameha''.
Research shows that sedentary lifestyle, coupled with an excessive intake of sugar-rich substances lead to a build up of toxins that could be equated to ''ama'' (or toxins resulting from improperly digested food and metabolic products). This ''ama'' then leads to the formation of ''meda'' (fat)<ref> Pandey Rashmi, Dubey N., Tripathi NS. Ayurvedic Concept of Lifestyle Ailments and its Healing Through Traditional Regimen., 2015, Scholars Journal of Applied Medical Sciences, 3(3H):1599-1601 </ref>. When this resultant ''meda'' is also coupled with vitiated ''doshas'' (primarily, ''kapha'' and ''vata''), and ''agni'' (the digestive processes), it provides for a conducive ground for the causation of ''prameha''.
Modern scientific research also correlates insulin resistance with obesity, where insulin resistance increases with weight gain and reduces with weight loss. Hormones such as resistin (derived from adipose tissues) provide for a direct link between obesity and diabetes, as they cause insulin resistance.
Modern scientific research also correlates insulin resistance with obesity, where insulin resistance increases with weight gain and reduces with weight loss. Hormones such as resistin (derived from adipose tissues) provide for a direct link between obesity and diabetes, as they cause insulin resistance.<ref> Kumar Manish, Kivadassanavar MB et al. Screening of Serum Insulin in Obese Individual WSR to Sthaulya: An Observational Study. 2016. European Journal of Pharmaceutical and Medical Research, 2016,3(9),638-640 </ref>
In [https://en.wikipedia.org/wiki/Ayurveda Ayurveda], much emphasis has been given to the role of ''meda'' in the pathogenesis of ''prameha''. However, its role is not only as a ''dushya'' (disturbed functioning of the ''dhatus''), but something more than that. ''Bahudrava shleshma'' (''kapha'' that contains too much liquid) joins and affects ''meda'', causing it to become ''abadha'' (unobstructed or fluid) in nature. This form of ''meda'' has been described to have an effect on ''mamsa'' (muscle tissue), thereby increasing the volume of body fluid. This has been described as ''sharira- kleda'' (body fluid). This route of pathogenesis for ''prameha'' is closely related to obesity.
In [https://en.wikipedia.org/wiki/Ayurveda Ayurveda], much emphasis has been given to the role of ''meda'' in the pathogenesis of ''prameha''. However, its role is not only as a ''dushya'' (disturbed functioning of the ''dhatus''), but something more than that. ''Bahudrava shleshma'' (''kapha'' that contains too much liquid) joins and affects ''meda'', causing it to become ''abadha'' (unobstructed or fluid) in nature. This form of ''meda'' has been described to have an effect on ''mamsa'' (muscle tissue), thereby increasing the volume of body fluid. This has been described as ''sharira- kleda'' (body fluid). This route of pathogenesis for ''prameha'' is closely related to obesity.