Difference between revisions of "Langhana"
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− | + | <p style="text-align:justify;">The word ‘langhana’ represents therapeutic fasting, hunger or intentional starving.<ref>Monier-Williams, Monier-Williams Sanskrit- English Dictionary, 1st edition; Oxford University Press, Langhana, Page 895</ref> In broader perspective, it includes the therapies intended for reducing or depleting or lightening the body components. This is one among the six basic treatment protocols in Ayurveda. [Cha.Sa.[[Sutra Sthana]] 22/4] This therapy is applied to reduce any abnormally increased body component and bring it back to normal level to maintain equilibrium. It is indicated in the abnormal accumulation of [[dosha]] ([[pitta]]/[[kapha]]/[[rakta]]), any waste product, state of [[dosha]] associated with [[ama]], and indigestion. Langhana therapy can be advised with or without any medication. [Chakrapani on Cha.Sa.[[Sutra Sthana]] 22/12-13] <br/> | |
− | The word ‘langhana’ represents therapeutic fasting, hunger or intentional starving.<ref>Monier-Williams, Monier-Williams Sanskrit- English Dictionary, 1st edition; Oxford University Press, Langhana, Page 895</ref> In broader perspective, it includes the therapies intended for reducing or depleting or lightening the body components. This is one among the six basic treatment protocols in Ayurveda. [Cha.Sa.[[Sutra Sthana]] 22/4] This therapy is applied to reduce any abnormally increased body component and bring it back to normal level to maintain equilibrium. It is indicated in the abnormal accumulation of [[dosha]] ([[pitta]]/[[kapha]]/[[rakta]]), any waste product, state of [[dosha]] associated with [[ama]], and indigestion. Langhana therapy can be advised with or without any medication. [Chakrapani on Cha.Sa.[[Sutra Sthana]] 22/12-13] | ||
Langhana therapy is highly effective and increasingly popular in management of diseases due to overnutrition. The most popular forms of langhana therapy are fasting (upavasa) and exercise ([[vyayama]]). This article deals with various forms of langhana therapy in broader perspectives. | Langhana therapy is highly effective and increasingly popular in management of diseases due to overnutrition. The most popular forms of langhana therapy are fasting (upavasa) and exercise ([[vyayama]]). This article deals with various forms of langhana therapy in broader perspectives. | ||
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{{Infobox | {{Infobox | ||
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|label2 = Authors | |label2 = Authors | ||
− | |data2 =Aneesh E.G.<sup>1</sup>, Choudhary Sujata <sup>2</sup>, Deole Yogesh S. <sup>1</sup> | + | |data2 =Aneesh E.G.<sup>1</sup>, Choudhary Sujata <sup>2</sup>, [[Yogesh Deole|Deole Yogesh S.]]<sup>1</sup> |
|label3 = Reviewed and Edited by | |label3 = Reviewed and Edited by | ||
− | |data3 = Basisht G.<sup>1</sup> | + | |data3 = [[Gopal Basisht|Basisht G.]]<sup>1</sup> |
|label4 = Affiliations | |label4 = Affiliations | ||
− | |data4 = <sup>1</sup>[[Charak Samhita Research, Training and Development Centre]], I.T.R.A., Jamnagar, India, <sup>2</sup>Assistant professor, Shri Santanpal Singh Ayurved Medical College and Hospital, Mirzapur, Shahjahanpur, Uttar Pradesh, India | + | |data4 = <sup>1</sup>[[Charak Samhita Research, Training and Development Centre]], I.T.R.A., Jamnagar, India, |
+ | <sup>2</sup>Assistant professor, Shri Santanpal Singh Ayurved Medical College and Hospital, Mirzapur, Shahjahanpur, Uttar Pradesh, India | ||
|label5 = Correspondence email: | |label5 = Correspondence email: | ||
− | |data5 = carakasamhita@gmail.com | + | |data5 = draneesheg@gmail.com, |
+ | sujata.choudhary.7330@gmail.com, | ||
+ | dryogeshdeole@gmail.com, | ||
+ | carakasamhita@gmail.com | ||
+ | |||
+ | |label6 = Publisher | ||
+ | |data6 = [[Charak Samhita Research, Training and Development Centre]], I.T.R.A., Jamnagar, India | ||
− | | | + | |label7 = Date of first publication: |
− | | | + | |data7 = April 1, 2021 |
− | | | + | |label8 = DOI |
− | | | + | |data8 = 10.47468/CSNE.2021.e01.s09.047 |
}} | }} | ||
Latest revision as of 09:47, 24 February 2024
The word ‘langhana’ represents therapeutic fasting, hunger or intentional starving.[1] In broader perspective, it includes the therapies intended for reducing or depleting or lightening the body components. This is one among the six basic treatment protocols in Ayurveda. [Cha.Sa.Sutra Sthana 22/4] This therapy is applied to reduce any abnormally increased body component and bring it back to normal level to maintain equilibrium. It is indicated in the abnormal accumulation of dosha (pitta/kapha/rakta), any waste product, state of dosha associated with ama, and indigestion. Langhana therapy can be advised with or without any medication. [Chakrapani on Cha.Sa.Sutra Sthana 22/12-13]
Langhana therapy is highly effective and increasingly popular in management of diseases due to overnutrition. The most popular forms of langhana therapy are fasting (upavasa) and exercise (vyayama). This article deals with various forms of langhana therapy in broader perspectives.
Section/Chapter/topic | Chikitsa / Langhana |
---|---|
Authors | Aneesh E.G.1, Choudhary Sujata 2, Deole Yogesh S.1 |
Reviewed and Edited by | Basisht G.1 |
Affiliations |
1Charak Samhita Research, Training and Development Centre, I.T.R.A., Jamnagar, India, 2Assistant professor, Shri Santanpal Singh Ayurved Medical College and Hospital, Mirzapur, Shahjahanpur, Uttar Pradesh, India |
Correspondence email: |
draneesheg@gmail.com, sujata.choudhary.7330@gmail.com, dryogeshdeole@gmail.com, carakasamhita@gmail.com |
Publisher | Charak Samhita Research, Training and Development Centre, I.T.R.A., Jamnagar, India |
Date of first publication: | April 1, 2021 |
DOI | 10.47468/CSNE.2021.e01.s09.047 |
Contextual and literal meanings
Etymology and derivation
Langhana is derived from the root word ‘langha’ by adding ‘lyut’ suffix to it. It means fasting (upavasa). [Shabdakalpadruma]
Definition
The procedures which produce lightness or reduction in the body components are called ‘langhana’. [Cha.Sa.Sutra Sthana 22/10]
Synonym and other meaning
Apatarpana (restricted nutrition) is often used as synonymous to langhana. [A.Hr. Sutra Sthana 14/2][2] The word ‘langhana’ also denotes act of jumping, stepping across, leaping, or mounting. [Cha.Sa.Nidana Sthana 8/11] [Cha.Sa.Vimana Sthana 6/18]
Properties
The lightening therapy can be administered by diet, actions, medicines, procedures having following properties:
- Lightness (laghu): This is the essential property of any eatable substance by which it becomes easily digestible. These are usually low energy dense foods having a low satiety index.
- Hot (ushna): Substances bearing hot potency are suitable for pacifying kapha, vata and undigested biological waste (amadosha).This property stimulates digestion and metabolism.
- Sharpness/ intense (tikshna): With this quality, the therapeutic substances can quickly cross biological barriers and penetrate the subtler body channels to show strong effect.
- Clearing (vishada): This property is applied for removing the accumulated body waste to cleanse up body channels.
- Dryness(ruksha): By this property, the moisture and unctuousness is absorbed leading to lightness.
- Subtleness (sukshma): This property helps the drugs to reach into the minute body channels.
- Roughness (khara): Roughness promotes movement of obstructed sticky body components to cleanse up channels.
- Unstable/flowing (sara): Sara property improves flow and proper channelization of body waste for excretion.
- Hard (kathina): Substances without water or unctuousness are hard in consistency.[Cha.Sa.Sutra Sthana 22/12-13]
These are applied in langhana therapy to reduce fat and moisture components.
Panchamahabhuta composition
The agni, vayu and akasha mahabhuta play predominant and vital role in mechanism of langhana therapy. [A.S. Sutra Sthana 24/3][3]
Methods of langhana therapy
The methods of langhana therapy are broadly classified into:
I. Purifying (shodhana) procedures
II. Pacifying (shamana) procedures [A.Hr. Sutra Sthana 14/4][2]
Purifying (shodhana) procedures
This includes following procedures which are applied in patients having good strength (bala) and more severe conditions.
1.Enema with decoction (niruha basti)
2.Therapeutic emesis (vamana)
3.Therapeutic purgation (virechana)
4.Intranasal drug administration (shirovirechana/ nasya)
5.Bloodletting (asravisruti/ raktamokshana)[A.Hr. Sutra Sthana 14/5][2]
Pacifying (shamana) procedures
Following procedures are applied in weak patients and with mild to moderate disease conditions.
6.Carminatives (pachana)
7.Appetizers (dipana)
8.Withstanding hunger (kshut)/therapeutic fasting by restricting food
9.Withstanding thirst (trit)/restricted water or liquid intake
10.Exercise/physical activities (vyayama)
11.Exposure to sunlight (atapa)
12.Exposure to wind/breathing exercises (maruta) [A.Hr. Sutra Sthana 14/6-7][2]
Bloodletting (asravisruti) and appetizers (deepana) are excluded from langhana therapy by Charaka.[Cha.Sa.Sutra Sthana 22/18]
Indications
Langhana therapy is indicated in following individuals and conditions:
- Persons who used to consume excess unctuous food
- Excess body discharges
- Those who had undergone nourishing therapies. [Cha.Sa.Sutra Sthana 22/24]
- In state of accumulation of undigested/toxic biological waste (ama) [Su.Sa.UttaraSthana 40/34][4]
- In state of nutritive fluid (rasa dhatu) associated with ama [Cha.Sa.Chikitsa Sthana 15/75]
- As a part of post therapeutic regimen after therapeutic emesis (vamana) and therapeutic purgation (virechana) where digestive power is weak.
- In diseases like jwara, stiffness of thighs (urustambha), herpes (visarpa), abscess (vidradhi), splenic diseases(pleeha), obesity (sthaulya), diseases of head, throat and eyes [A.S.Sutra Sthana 24/10][3] skin disorders (kushtha), urinary disorders (prameha). [Cha.Sa.Sutra Sthana 22/24]
Specific indications
Purifying procedures
- In conditions of excessive accumulation of kapha, pitta, blood and waste products (mala).
- Obstruction of vata by morbidities
- Those who have good physical strength and bulky stature. [Cha.Sa.Sutra Sthana 22/19]
- Jwara, vomiting, diarrhea, cardiac complaints, constipation, heaviness, belching, nausea etc. [A.Hr. Sutra Sthana 14/12][2]
Digestive measures (pachana)
- Diseases of moderate severity
- Diseases having kapha and pitta predominance
- Vomiting, diarrhea, heart disease, acute intestinal irritation, intestinal sluggishness, fever, constipation, heaviness of body, eructation, nausea and anorexia [Cha.Sa.Sutra Sthana 22/20-21]
Restricted food and water consumption
- Mild diseases [Cha.Sa.Sutra Sthana 22/22]
- Restricted intake of liquid or water results in pacification of kapha and pitta dosha due to depletion of their source i.e. jala mahabhuta.
- By restriction of food, the agni (digestion and metabolism) is improved first and it hastens the process of normalizing dosha equilibrium. [A.Hr.Chikitsa Sthana 10/91][2]
Physical exercise (vyayama), exposure to sunlight (aatapa) and exposure to wind/breathing exercise (maruta)
- Mild to moderate intensity diseases for patients with good physical strength [Cha.Sa.Sutra Sthana 22/23]
Contraindications
In some diseases, langhana therapy can worsen the conditions due to degeneration of body components. Hence, it is contraindicated in following conditions:
- Vata predominant conditions
- Conditions of fear, anger, grief and physical exertion [Cha.Sa.Chikitsa Sthana 3/139]
- Jwara with excess dominance of pitta dosha [A.S.Chikitsa Sthana 1/13][3]
- Jwara due to exogenous causes (agantujaj wara) and chronic stage (jeerna jwara) [A.S.Chikitsa Sthana 1/17][3]
Assessment of therapy
Langhana therapy is always prescribed after assessment of strength of the individual and severity of disease. It is administered for specific duration and in specific dose as per the personified conditions. Assessment of effect is done by clinical observation of features. The therapy is stopped after attaining equilibrium of body components and observing following features.
Features of optimal langhana
- Proper evacuation of flatus, urine and feces
- Feeling of lightness in the body
- Feeling of clarity in heart, eructation, throat and mouth
- Disappearance of drowsiness and exhaustion
- Appearance of perspiration
- Reappearance of taste, hunger and thirst
- Feeling of wellbeing [Cha.Sa.Sutra Sthana 22/34-35]
- Intolerance to hunger and thirst [Su.Sa. Uttara Sthana 39/105][4]
- Clarity of sense organs [A.Hr. Sutra Sthana 14/17][2]
Features of excessive administration of langhana
Excess administration of langhana therapy leads to degeneration of body components and following clinical features are observed.
- Pain in the joints
- Body ache
- Cough
- Dryness of the mouth
- Complete loss of hunger
- Anorexia
- Thirst
- Diminished hearing and vision
- Confusion of mind
- Frequent eructation
- Fainting
- Frequent upward movement of vata
- Loss of body weight, digestive power and strength[Cha.Sa.Sutra Sthana 22/36-37]
- Excess emaciation
- Loss of sleep
- Delirium
- Depletion and non-elimination of feces and urine [A.Hr. Sutra Sthana 14/29-30][2]
- Occurrence of secondary disease like dyspnea [Su.Sa.Uttara Sthana. 39/106][4]
Untoward effects of improper follow up of langhana therapy
Improper fasting (langhana) may lead to untoward effects and etiopathogenesis of certain diseases/conditions like:
Emaciation of body [Cha.Sa.Sutra Sthana 21/11], wasting disorders due to over exertion (sahasaja rajayakshama) [Cha.Sa.Chikitsa Sthana 8/14], hemorrhoid [Cha.Sa.Chikitsa Sthana 14/13], excessive thirst (trishna) [Cha.Sa.Chikitsa Sthana 22/4], diseases of thigh (urustambha). [Cha.Sa.Chikitsa Sthana 27/9]
Therefore, langhana therapies should be performed to the extent that it does not hamper the vitality or strength of the individual. [Cha.Sa.Chikitsa Sthana 3/141]
Benefits
Langhana leads to pacification of dosha, improves strength of digestive power (agni), lightness in body promotes healthy state, hunger, thirst, desire for food, strength and vigor. [A.S.Chikitsa Sthana 1/3][3]
Importance in diagnosis
Craving for fasting (langhana) is diagnostic feature in conditions of occlusion of vata by excess vitiated kaphadosha. [Cha.Sa.Chikitsa Sthana 28/63]
Importance in preservation of health and prevention
Langhana therapy is more indicated in winter season (shishira and hemanta) to maintain equilibrium. [Cha.Sa.Sutra Sthana 22/24][A.Hr. Sutra Sthana 14/11][2] In case of accumulation of toxic biological waste (ama) and in obese persons, lightening therapy (langhana) should be done daily. [A.Hr. Sutra Sthana 14/10-11][2] The seasonal purification procedures play vital role in preservation of health and prevention of disease.
Importance in management of disease
Therapeutic fasting (upawasa) is indicated in mild vitiation of dosha. It stimulates digestive power (agni) and normal functions of vatadosha. [Cha.Sa.Vimana Sthana 3/44]
Langhana therapies especially fasting is the first line of therapy in many disorders. It is advocated in the initial stage of following diseases.
- Jwara [Cha.Sa.Chikitsa Sthana 3/139] can be treated with only fasting (langhana) [Cha.Sa.Nidana Sthana 8/31] if it is associated with toxic metabolic waste (ama) or during the predominance of kapha or kapha and pitta dosha. [Cha.Sa.Chikitsa Sthana 3/284] The kapha predominant stage of chronic intermittent pattern of jwara can also be managed through reducing (langhana) therapies. [Cha.Sa.Chikitsa Sthana 3/295] The patients who are unsuitable for oleation and purificatory therapies are treated by langhana therapies. [Su.Sa.Uttara Sthana 39/99][4]
- Bleeding disorders (raktapitta) especially through the upper orifices (eyes, mouth and nose) as it is associated with pitta along with toxic biological waste (sama pitta) and kaphadosha. [Cha.Sa.Chikitsa Sthana 4/30]
- Abdominal tumors (gulma) caused due to kaphadosha. [Cha.Sa.Chikitsa Sthana 5/49]
- Swelling associated with toxic biological waste (ama) [Cha.Sa.Chikitsa Sthana 12/17]
- Noninfectious gastroenteritis (visuchika). [Cha.Sa.Vimana Sthana 2/13]
- Vomiting (chchardi) as it is considered to be originating from the agitations of the doshas in the stomach (amashaya). [Cha.Sa.Chikitsa Sthana 20/20]
- All diseases which originates from the stomach (amashaya) can be treated through fasting (langhana). [Cha.Sa.Nidana Sthana 8/31]
- In all disorders of nutritive fluid (rasa)[Cha.Sa.Sutra Sthana 28/25] and the conditions affecting mouth and oral cavity. [Cha.Sa.Chikitsa Sthana 12/80]
- Bleeding hemorrhoids with kapha and pitta aggravation [Cha.Sa.Chikitsa Sthana 14/176], Diabetes mellitus (prameha) caused by kapha [Cha.Sa.Chikitsa Sthana 6/25], ulcers with kapha predominance [Cha.Sa.Chikitsa Sthana 25/16], rhinitis of kapha origin (kaphaja pinasa) associated with heaviness and anorexia [Cha.Sa.Chikitsa Sthana 26/149], Cardiac disorders [Cha.Sa.Chikitsa Sthana 26/100] and diseases caused by the suppression of urge of vomiting. [Cha.Sa.Sutra Sthana 7/15]
- Mild aggravated dosha should be managed by fasting therapy (langhana) in case of diarrhea. [Cha.Sa.Chikitsa Sthana 19/19]
- In the prodormal stage of all varieties of erysipelas (visarpa). [A.S.Chikitsa Sthana 20/2][3] If erysipelas (visarpa) is caused with dosha in the state of incomplete transformation (ama) and is located in thorax and upper body parts (kaphasthana), fasting therapy (langhana) is beneficial. [Cha.Sa.Chikitsa Sthana 21/44]
- Fissure in ano if associated with ama. [Cha.Sa.Siddhi Sthana 6/63]
- Indigestion caused due to ama (amajeerna). [Su.Sa.Sutra Sthana. 46/505][4]
- Bloating in upper abdomen (anaha) caused by improperly digested food/product of improper digestion (ama), associated with stiffness in cardiac region, diseases of head and heaviness, retention of belching, common cold should be treated with fasting therapy (langhana). [Cha.Sa.Chikitsa Sthana 26/26]
Precaution
The diseases treated by fasting etc. without purification therapies may recur due to incomplete elimination of morbid dosha. Hence, purification therapies are important to prevent recurrence of disease. [Cha.Sa.Sutra Sthana 16/20]
Physiology of fasting
The process of improvement in digestion and metabolic processes by fasting can be related to physiological mechanisms like glycogenolysis and lipolysis.
When a person follows fasting, the energy is derived by utilization of blood glucose. After that, glycogen stored in hepatocytes is utilized for energy. This also accelerates the breakdown of adipose tissue i.e. lipolysis. Thus, more fatty acids and glycerol are formed and released into blood. At the same time the other cells may produce ketones. The fatty acids are transported into hepatocytes, get metabolized and produce ketones beta-OHB and acetoacetate. This induces mitochondrial biogenesis.
The ketones thus produced are transported into cells with high metabolic activity such as neurons, muscles etc., becomes acetyl coenzyme A. It enters the tricarboxylic acid (TCA) cycle where ATP is generated. Thus, during fasting, primary energy source of the body shifts from glucose to fatty acids and ketones.[5]
The ultimate beneficial effect of fasting is reduction in adipose tissue (meda dhatu) and kaphadosha.
Current researches
In a study conducted on 59 patients having poor digestive power, it is reported that the langhana therapies, fasting and digestive medicine, Zingiber officinale (shunthi), improves appetite, food intake and enthusiasm. It makes the body feel lighter and also aids in normal excretion of urine and feces. The digestive power influences the state of dosha in the absence of food. The body regains its normalcy once the vitiated dosha are in equilibrium state after digestion (paka).[6]
Fasting therapy results in significant reduction in weight and body mass index (BMI). In a study conducted on 44 healthy individuals, short-term fasting therapy is compared with low calorie diet. Significant reduction in weight and Leptin levels were achieved through fasting than low calorie diet. Increased beta-oxidation is observed during fasting.[7]
Average life span is increased by 30%, when the rats were maintained on alternate day fasting. Plasma glucose, insulin and leptin levels were low for the rats maintained on fasting. Ketone and adiponectin levels were more. Inflammatory markers were found to be reduced in liver of rats kept on time restricted feeding. The normal decline in muscle mass during ageing is found to be prevented by caloric restriction in mice. Fasting stimulates autophagy in muscles. Cardiovascular stress adaptations were noted in rats kept on alternate day fasting. It also increases brain derived neurotrophic factor which plays a major role in synaptic plasticity and neurogenesis.[5]
Relevance of fasting (upawasa) and autophagy
Recently, the Noble prize for the year 2016 in physiology is awarded to Yoshinori Ohsumi for his research ‘autophagy’. Autophagy denotes “self-eating”. This concept emerged during the 1960’s, when researchers first observed that the cell could destroy its own contents by enclosing it in membranes, forming sack-like vesicles that were transported to a recycling compartment, called the lysosome, for degradation. The phenomenon was not well understood until a series of brilliant experiments were performed by the researcher in the early 1990’s. He used Baker’s yeast to identify genes essential for autophagy. He elucidated the underlying mechanisms for autophagy in yeast and showed that similar sophisticated machinery is used in human cells. He cultured mutated yeast lacking vacuolar degradation enzymes and simultaneously stimulated autophagy by starving the cells. Within hours, the vacuoles were filled with small vesicles that had not been degraded. These vesicles were nothing but autophagosomes and so the experiment proved that autophagy exists in yeast cells.[8] Langhana therapy may work on the lines of autophagy, which may trigger the formation of autophagosomes to clear the unwanted accumulated substances. The vitiated dosha are responsible for mutation in body tissues. The abnormal states of dosha are transformed after langhana therapies. Further research on effect of langhana therapies on autophagy may provide valuable clues in prevention and management of diseases.
Current strategies of fasting and langhana therapy
In current times, a pattern of intermittent fasting is advised for health benefits and management of metabolic diseases. Intermittent fasting, or intermittent energy restriction, includes various meal timing schedules that cycle between voluntary fasting (or reduced calorie intake) and non-fasting over a given period.[9] Methods of intermittent fasting include alternate-day fasting (ADF), periodic fasting, and daily time-restricted feeding. The other strategies of fasting include calorie restricted diet, periodic fasting, fasting-mimicking diet, meal frequency and meal timing.
Ayurveda advised taking meals in proper quantity, at proper time and with proper methods (ahara vidhi) for preservation of health. A group of researchers observed kaalabhojana (optimal food at proper time) has additional health benefits over time restricted feeding. Kalabhojanam does not mean that food can be taken at will during the 24 hours. It must be in coherence with daily regimen (dinacharya) and sleep-wake timings as per day-night cycle. Consuming food just once a day is the best strategy [Cha.Sa. Sutra Sthana 25/40] and will automatically have a longer fasting period. The second meal shall be in accordance agni and sleep cycle. Thus, the feeding time must remain restricted during morning to evening (i.e., a maximum of 12-hour eating window during day and thus a minimum 12-hour gap during night), and not during the night. Thus, it extends the window between evening meal and morning meal. This may vary as per the digestion capacity and body constitution of individual.[10] The personified langhana therapies can be more beneficial as per the guidelines described above after consideration of body constitution, state of dosha, strength of individual and digestion capacity. These guidelines, if followed while prescribing fasting strategies can yield more health benefits.
Fasting is beneficial in metabolic syndrome by decreasing fasting glucose, fasting insulin and insulin resistance. It also reduces the cardiovascular risk factors like total cholesterol, LDL, triglycerides etc. In diabetic patients improved insulin sensitivity and glucose tolerance was reported immediately after a fast.[5]
List of theses
- Dharmi P Bhuva (2013): Fundamental and applied aspect of karma as karana in Ayurveda w.s.r. to langhana karma. Department of basic principles. IPGT&RA Jamnagar
More information
Abbreviations
Cha. = Charak, Su. = Sushruta, A. = Ashtanga, S. = Sangraha, Hr. = Hridayam, Sa. = Samhita.
List of References
The list of references for langhana in Charak Samhita can be seen here.
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References
- ↑ Monier-Williams, Monier-Williams Sanskrit- English Dictionary, 1st edition; Oxford University Press, Langhana, Page 895
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 2.9 Vagbhata. Ashtanga Hridayam. Edited by Harishastri Paradkar Vaidya. 1st ed. Varanasi: Krishnadas Academy;2000.
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 Vridha Vagbhata, Ashtanga Sangraha. Edited by Shivaprasad Sharma. 3rd ed. Varanasi: Chaukhamba sanskrit series office;2012.
- ↑ 4.0 4.1 4.2 4.3 4.4 Sushruta. Sushruta Samhita. Edited by Jadavaji Trikamji Aacharya. 8th ed. Varanasi: Chaukhambha Orientalia;2005.
- ↑ 5.0 5.1 5.2 Anton SD, Moehl K, Donahoo WT, Marosi K, Lee SA, Mainous AG 3rd, Leeuwenburgh C, Mattson MP. Flipping the Metabolic Switch: Understanding and Applying the Health Benefits of Fasting. Obesity (Silver Spring). 2018 Feb;26(2):254-268. doi: 10.1002/oby.22065. Epub 2017 Oct 31. PMID: 29086496; PMCID: PMC5783752.
- ↑ Rajani A, Vyas MK, Vyas HA. Comparative study of Upavasa and Upavasa with Pachana in the management of Agnisada. Ayu. 2010 Jul;31(3):351-4. doi: 10.4103/0974-8520.77166. PMID: 22131738; PMCID: PMC3221070.
- ↑ Shetty P, Dinesh S, Halappa NG, Rajany T. Comparing the effects of short-term fasting therapy and low-calorie diet on anthropometric and leptin measures among obese or overweight persons: Randomized controlled trial. Ancient Sci Life 2018;37:133-40.
- ↑ Ohsumi Y. Yoshinori Ohsumi: autophagy from beginning to end. Interview by Caitlin Sedwick. J Cell Biol. 2012;197(2):164-165. doi:10.1083/jcb.1972pi
- ↑ de Cabo, Rafael; Mattson, Mark P. (December 2019). "Effects of intermittent fasting on health, aging, and disease". New England Journal of Medicine. 381 (26): 2541–51. doi:10.1056/NEJMra1905136. PMID 31881139. Available from https://en.wikipedia.org/wiki/Intermittent_fasting accessed on 30/03/2021
- ↑ Prakash NP et.al. Prevention of metabolic risks by Kalabhojanam strategy of Ayurveda.Annals of Ayurvedic Medicine 2020; 9(2):116-129. Available from https://www.aamjournal.in/fulltext/70-1590829531.pdf