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'''Understanding congenital disorders in [[Ayurveda]] and contemporary research'''  

'''Understanding congenital disorders in [[Ayurveda]] and contemporary research'''  

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<p style='text-align:justify;'>Congenital disorders are disabilities or malformations present at or before birth.  These are identified in prenatal life or at birth, or many years later. As per the World Health Organization, congenital anomalies are a leading cause of neonatal deaths. Every year an estimated 295 000 newborns die within 28 days of birth due to congenital anomalies. These can contribute to long-term disability, with significant impacts on individuals, families, healthcare systems, and societies. <ref>Available from https://www.who.int/news-room/fact-sheets/detail/congenital-anomalies accessed on 15/06/2021</ref>

Congenital disorders are disabilities or malformations present at or before birth.  These are identified in prenatal life or at birth, or many years later. As per the World Health Organization, congenital anomalies are a leading cause of neonatal deaths. Every year an estimated 295 000 newborns die within 28 days of birth due to congenital anomalies. These can contribute to long-term disability, with significant impacts on individuals, families, healthcare systems, and societies. <ref>Available from https://www.who.int/news-room/fact-sheets/detail/congenital-anomalies accessed on 15/06/2021</ref>

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Human genetics studies individual genes, their role and function in disease, and their mode of inheritance.  Genomics refers to an organism's entire genetic information, the genome，and the function and interaction of DNA within the genome， as well as with environmental or nongenetic factors such as a person's lifestyle.  Characterization of the human genome in genomic studies has supported genetics to elucidate the etiology, pathogenesis of the disease, and improve therapeutic interventions and outcomes. The impressive advances in genetics, genomics， and health care information technology have significantly increased the wealth of knowledge. It is helpful in medical practice and play a prominent role in the diagnosis， prevention, and treatment of disease.<ref>J. Larry Ja meson， Peter Kopp. Principles of Human Genetics. In Harrison’s principles of internal medicine. 19th edition. Pg. 425. </ref>   

Human genetics studies individual genes, their role and function in disease, and their mode of inheritance.  Genomics refers to an organism's entire genetic information, the genome，and the function and interaction of DNA within the genome， as well as with environmental or nongenetic factors such as a person's lifestyle.  Characterization of the human genome in genomic studies has supported genetics to elucidate the etiology, pathogenesis of the disease, and improve therapeutic interventions and outcomes. The impressive advances in genetics, genomics， and health care information technology have significantly increased the wealth of knowledge. It is helpful in medical practice and play a prominent role in the diagnosis， prevention, and treatment of disease.<ref>J. Larry Ja meson， Peter Kopp. Principles of Human Genetics. In Harrison’s principles of internal medicine. 19th edition. Pg. 425. </ref>   

The ancient rishis of [[Ayurveda]] had recognized the genetic basis of diseases. They have documented the knowledge in various contexts. The current medical system focuses on the identification of genes responsible for diseases. At the same time, the references found in [[Ayurveda]] texts indicate the causes of genetic disorders and their role in health and diseases. A proper study to bridge the gaps and connect these two pools of information can reveal significant insights for a comprehensive understanding of why and what of congenital and genetic disorders.  The present article describes congenital disorders in [[Ayurveda]] texts and contemporary research.

<br/>The ancient rishis of [[Ayurveda]] had recognized the genetic basis of diseases. They have documented the knowledge in various contexts. The current medical system focuses on the identification of genes responsible for diseases. At the same time, the references found in [[Ayurveda]] texts indicate the causes of genetic disorders and their role in health and diseases. A proper study to bridge the gaps and connect these two pools of information can reveal significant insights for a comprehensive understanding of why and what of congenital and genetic disorders.  The present article describes congenital disorders in [[Ayurveda]] texts and contemporary research.

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