Interaction of [[dosha]]-[[dhatu]] (samurchhana) is the basis of pathogenesis. The state of [[agni]] should be considered in the pathogenesis. Any derangement of [[dosha]], if not corrected properly, progresses deeper into the [[dhatu]]s and becomes more challenging to correct. Progressive pathogenesis in any [[dhatu]] should be controlled by specific measures, otherwise it affects other sequential [[dhatu]]s. [Su.Sa.Sutra Sthana 21] So the role of dhatvagni is very important for metabolic disorders like dyslilipdemia (medoroga), obstinate urinary disease including diabetes ([[prameha]]), obesity (sthaulya). [[Agni]] and ultimately the dhatvagni are the basic concepts that are important to rule out the cause and treatment of any disease. The crucial aspects of concept of dhatvagni can be summarized as shown in Figure 1 | Interaction of [[dosha]]-[[dhatu]] (samurchhana) is the basis of pathogenesis. The state of [[agni]] should be considered in the pathogenesis. Any derangement of [[dosha]], if not corrected properly, progresses deeper into the [[dhatu]]s and becomes more challenging to correct. Progressive pathogenesis in any [[dhatu]] should be controlled by specific measures, otherwise it affects other sequential [[dhatu]]s. [Su.Sa.Sutra Sthana 21] So the role of dhatvagni is very important for metabolic disorders like dyslilipdemia (medoroga), obstinate urinary disease including diabetes ([[prameha]]), obesity (sthaulya). [[Agni]] and ultimately the dhatvagni are the basic concepts that are important to rule out the cause and treatment of any disease. The crucial aspects of concept of dhatvagni can be summarized as shown in Figure 1 |