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<p style='text-align:justify;'>As an important phase of pathogenesis (samprapti), the vitiated dosha travel and settle at the suitable places. [Madhu Kosha commentary on Madhava Nidana Sarvaroga Nidana Adhyaya]<ref name="ref2">Madhavakara ,Madhav Nidana with Madhukosha commentary by Vijayrakshita and Shreekanthadatta revised and edited by Prof. Yadunanda Upadhyaya ,Sarvaroganidana Adhyaya , 1/10 , Page No. 60 </ref> This is termed as prasara (sthana samshraya). It can be said that for both of these phases, roga-marga plays a vital role. Also, the movement of dosha (dosha gati) mentioned as normal (prakriti) and abnormal (vaikrita) are with the same nomenclature viz. koshtha, shakha, marma-asthi-sandhi. This shows the significance of roga marga from physiological view point (prakrita gati of dosha). <br/>Roga marga also contributes to the prognosis of the diseases. [Chakrapani commentary on Cha. Su. 11/48]<ref name="ref3">Chakrapani commentary on Charaka istraishSamhita Sutrasthana , Tistraishaniya Adhyaya, 11/48reprinted 2020 , Chaukhamba Surbharati Prakashana , Varanasi , Page No. </ref> <br/>Further, rogamarga is explained for precise treatment. [Madhukosha Commentary on Madhava Nidana Sarvaroga Nidana Adhyaya]<ref name="ref4">Madhavakara ,Madhav Nidana with Madhukosha commentary by Vijayrakshita and Shreekanthadatta revised and edited by Prof. Yadunanda Upadhyaya ,Sarvaroganidana Adhyaya , 1/4 , Page No. 21 </ref></p>
<p style='text-align:justify;'>As an important phase of pathogenesis (samprapti), the vitiated dosha travel and settle at the suitable places. [Madhu Kosha commentary on Madhava Nidana Sarvaroga Nidana Adhyaya]<ref name="ref2">Madhavakara ,Madhav Nidana with Madhukosha commentary by Vijayrakshita and Shreekanthadatta revised and edited by Prof. Yadunanda Upadhyaya ,Sarvaroganidana Adhyaya , 1/10 , Page No. 60 </ref> This is termed as prasara (sthana samshraya). It can be said that for both of these phases, roga-marga plays a vital role. Also, the movement of dosha (dosha gati) mentioned as normal (prakriti) and abnormal (vaikrita) are with the same nomenclature viz. koshtha, shakha, marma-asthi-sandhi. This shows the significance of roga marga from physiological view point (prakrita gati of dosha). <br/>Roga marga also contributes to the prognosis of the diseases. [Chakrapani commentary on Cha. Su. 11/48]<ref name="ref3">Chakrapani commentary on Charaka istraishSamhita Sutrasthana , Tistraishaniya Adhyaya, 11/48reprinted 2020 , Chaukhamba Surbharati Prakashana , Varanasi , Page No. </ref> <br/>Further, rogamarga is explained for precise treatment. [Madhukosha Commentary on Madhava Nidana Sarvaroga Nidana Adhyaya]<ref name="ref4">Madhavakara ,Madhav Nidana with Madhukosha commentary by Vijayrakshita and Shreekanthadatta revised and edited by Prof. Yadunanda Upadhyaya ,Sarvaroganidana Adhyaya , 1/4 , Page No. 21 </ref></p>
== Etymology ==
<ol type="A" style='text-align:justify;'><li style="font-weight: bold;">Roga : <br/><span style="font-weight: normal;">The word roga is derived from the root ‘ruj’ which means unpleasant, discomfort or pain, to break or disintegrate. <br/>It is evident that roga is the outcome of the disintegration of equilibrium of dosha (or dhatusamyata) – Homeostasis, which culminates into pain – physical or psychological. [Arundatta on A.H.Nidana Sthana 1/1]<ref name="ref5">Arundatta commentary on Ashtang Hridaya edited by Pt. Hari Sadashiv Sastri Paradkar , Nidanasthana , Sarvaroganidana , 1/1 , reprinted 2018, Chaukhamba Sanskrit Sansthan , Varanasi , Page No. 440 </ref></span></li>
<li style="font-weight: bold;">Marga : <br/><span style="font-weight: normal;">The Sanskrit word marga means to go along, or path. [Shabda Kalpadrum]<ref name="ref6">Radhakantadeva, Vasu, v. and Vasu, h. (1886).Shabdakalpadrumah , Page No. 708 </ref> Marga is derived from the Sanskrit verb ‘mruj’ that means purified channel or route. The dictionary meanings of the word marga are path, way, manner, mode, methods, process, indicative of how pathogenesis is to take place. [Sir. M.M. Williams]<ref name="ref7">Monier-Williams, m. (1899). A Sanskrit-English dictionary , Page. No. 812</ref></span></li></ol>
<p style='text-align:justify;'>Rogamarga can be understood as the way of disease occurrence, progression and recurrence as well. The word Roga marga maybe understood as ‘A weak spot’ or ‘Costus specious’. <br/>Textbook of Pathology by Boyd quotes “The science of pathology seeks to determine the cause of disease, to discover how disease injures the patient, to describe the lesions produced, to follow how the lesions change as disease progresses, to understand how disease produces secondary effects in the patient, and to record how the lesions heal as the patient recovers.” -<ref name="ref8">Boyd, William. "Text-book of Pathology." (1953). </ref></p>
== Definition ==
<p style='text-align:justify;'>The external pathway of disease is called bahya rogamarga.<ref name="ref9">Hemadri commentary on Ashtang Hridaya edited by Pt. Hari Sadashiv Sastri Paradkar , Sutrasthana , Doshabhediya Adhyaya, 12/45 , reprinted 2018, Chaukhamba Sanskrit Sansthan , Varanasi , Page No. 200 </ref> [Hemadri and Arunadatta on A.H. Su. 12/45] By this meaning, abhyantara (internal) and madhyama (medial) roga marga will be interpreted as internal and medial pathway of disease respectively.
These definitions suggest the appearance of clinical features can be representing a particular roga marga. However, in some cases the pathogenesis can be different with different pathways. For example, carbuncles due to diabetes (prameha pitika) appearing in the bahya roga marga, needs additional treatments besides other diseases which occur in bhaya roga marga.<ref name="ref10">Bhojani Meera Et Al: A study on Nirdesha Chatushka of Charaka Samhita and applied aspect of Trayo-Rogamarga, MD Thesis, 2003, IPGT&RA, Jamnagar </ref> Hence, it can be interpreted that the dosha samprapti can travel to any roga marga during the process. </p>