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Line 144: − • The endometrium functions as a complex multicellular structure that involves interactions of immune, endocrine and vascular systems. The strict regulation of this tissue to allow cyclical ‘injury’ and ‘repair’ at menstruation results in a remarkable physiological response that allows pregnancy to occur. + − • Overall, 1753 genes were differentially expressed in one or more comparisons related to menstrual breakdown and repair. Significant canonical pathways, gene clusters and upstream regulators enriched during menstrual bleeding included those associated with immune cell trafficking, inflammation, cell cycle regulation, extracellular remodeling and the complement and coagulation cascade. + − • A non-invasive sampling method is developed by collecting menstrual blood and filtering endometrial tissue. In combination with advanced experimental technology, the sample of menstrual endometrium is studied further for researches on endometriosis, endometrial lesions or other menstruation-related diseases. + − • A study investigated the effects of donor age and passage number on the biological characteristics of menstrual blood-derived stem cells (MenSCs) by comparing MenSCs derived from donors with three different age ranges and after different passage times. Continuous passage, flat cloning, cell proliferation assays, flow cytometric phenotyping and whole human genome microarray were performed to systematically analyse the relationship between the self-renewal ability of MenSCs as well as their potential to maintain their stem cell characteristics and to resist aging. The results demonstrated that the immune phenotypes and in vitro cultural characteristics of MenSCs did not change significantly with the progression of aging. + − • Some studies have shown the evidences regarding the feeling like craving for certain type of food articles like chocolate in women during the menstrual phase. + − • Ayurveda emphasizes the importance of diet and life-style for maintaining the proper menstrual health. Dysmenorrhea, premenstrual syndrome (PMS), and menstrual irregularities are directly associated with dietary habits and physical activities. Diet, characterized by a high consumption of sugars, salty snacks, sweets and desserts, tea and coffee, salt, fruit juices and added fat (labeled as “snacks” pattern), is associated with an increased risk of dysmenorrhea among young women. + − • In a study, it is observed that smoking is associated with increased risk of reporting psychological and behavioral symptoms in premenstrual syndrome. High calorie/fat/sugar/salt foods intake is associated with increased risk of reporting physical symptoms. Fruit consumption shows decreased risk of reporting behavioral symptoms. + + + + + + + + +
→Current researches
==Current researches ==
==Current researches ==
*The endometrium functions as a complex multicellular structure that involves interactions of immune, endocrine and vascular systems. The strict regulation of this tissue to allow cyclical ‘injury’ and ‘repair’ at menstruation results in a remarkable physiological response that allows pregnancy to occur.
*Overall, 1753 genes were differentially expressed in one or more comparisons related to menstrual breakdown and repair. Significant canonical pathways, gene clusters and upstream regulators enriched during menstrual bleeding included those associated with immune cell trafficking, inflammation, cell cycle regulation, extracellular remodeling and the complement and coagulation cascade.
*A non-invasive sampling method is developed by collecting menstrual blood and filtering endometrial tissue. In combination with advanced experimental technology, the sample of menstrual endometrium is studied further for researches on endometriosis, endometrial lesions or other menstruation-related diseases.
*A study investigated the effects of donor age and passage number on the biological characteristics of menstrual blood-derived stem cells (MenSCs) by comparing MenSCs derived from donors with three different age ranges and after different passage times. Continuous passage, flat cloning, cell proliferation assays, flow cytometric phenotyping and whole human genome microarray were performed to systematically analyse the relationship between the self-renewal ability of MenSCs as well as their potential to maintain their stem cell characteristics and to resist aging. The results demonstrated that the immune phenotypes and in vitro cultural characteristics of MenSCs did not change significantly with the progression of aging.
*Some studies have shown the evidences regarding the feeling like craving for certain type of food articles like chocolate in women during the menstrual phase.
*Ayurveda emphasizes the importance of diet and life-style for maintaining the proper menstrual health. Dysmenorrhea, premenstrual syndrome (PMS), and menstrual irregularities are directly associated with dietary habits and physical activities. Diet, characterized by a high consumption of sugars, salty snacks, sweets and desserts, tea and coffee, salt, fruit juices and added fat (labeled as “snacks” pattern), is associated with an increased risk of dysmenorrhea among young women.
*In a study, it is observed that smoking is associated with increased risk of reporting psychological and behavioral symptoms in premenstrual syndrome. High calorie/fat/sugar/salt foods intake is associated with increased risk of reporting physical symptoms. Fruit consumption shows decreased risk of reporting behavioral symptoms.
===List of thesis done===
===List of thesis done===
1. Shinde Vaishali S.(2004) : A study on the concept of Upadhatu in Samhitas with applied aspect to Artava-Dushti. Samhita, department of basic principles , IPGT & RA .Jamnagar
1. Shinde Vaishali S.(2004) : A study on the concept of Upadhatu in Samhitas with applied aspect to Artava-Dushti. Samhita, department of basic principles , IPGT & RA .Jamnagar
==More information ==
==More information ==
[[Grahani Chikitsa]]
[[Grahani Chikitsa]]