Ayurveda text describe the formation of shukra dhatu from majja dhatu. Current research shows that bone marrow-derived mesenchymal stem cells (BM-MSCs) have the potential for differentiation. They secrete anti-inflammatory cytokines and growth factors which make them appropriate for cell therapy. A study conducted to evaluate the healing effect of BM-MSCs transplantation on germinal cells showed that the transplanted BM-MSCs could successfully induce spermatogenesis in seminiferous tubules of azoospermic hamster. Therefore, BM-MSCs can be an attractive candidate in cell transplantation of azoospermia.
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Ayurveda text describe the formation of shukra dhatu from majja dhatu. Current research shows that bone marrow-derived mesenchymal stem cells (BM-MSCs) have the potential for differentiation. They secrete anti-inflammatory cytokines and growth factors which make them appropriate for cell therapy. A study conducted to evaluate the healing effect of BM-MSCs transplantation on germinal cells showed that the transplanted BM-MSCs could successfully induce spermatogenesis in seminiferous tubules of azoospermic hamster. Therefore, BM-MSCs can be an attractive candidate in cell transplantation of azoospermia.<ref> Tamadon A et al, Induction of Spermatogenesis by Bone Marrow-derived Mesenchymal Stem Cells in Busulfan-induced Azoospermia in Hamster,Int J Stem Cells. 2015 Nov;8(2):134-45. doi: 10.15283/ijsc.2015.8.2.134</ref>