Changes

In current perspective of human physiology, the seven dhatu correspond to seven kinds of basic tissues as below:  

In current perspective of human physiology, the seven dhatu correspond to seven kinds of basic tissues as below:  

Rasa: plasma including interstitial fluid and lymph  

[[Rasa]]: plasma including interstitial fluid and lymph  

Rakta: elements of blood and electrolytes  

[[Rakta]]: elements of blood and electrolytes  

Mamsa: muscle tissue  

[[Mamsa]]: muscle tissue  

Meda: adipose tissue  

[[Meda]]: adipose tissue  

Asthi: bone tissue  

[[Asthi]]: bone tissue  

Shukra: elements of reproductive tissues <ref> Dwarkanath C. Introduction to Kayachikitsa. Chaukhambha Orientalia. Varanasi; 1996. Third edition.pg.318 </ref>

[[Shukra]]: elements of reproductive tissues <ref> Dwarkanath C. Introduction to Kayachikitsa. Chaukhambha Orientalia. Varanasi; 1996. Third edition.pg.318 </ref>

'''Dhatvagni and tissue metabolism:'''  

'''Dhatvagni and tissue metabolism:'''  

The tissue metabolism corresponds to functions of dhatvagni at various levels as below:<ref>Amardeep Kour, Gupta Vikas, Sodhi Danisha. Importance of Nyayas on Body’s Well-Being – A Conceptual Study. Int J Ayu Pharm Chem 2015 Vol. 4 Issue 1.pg.95-106 available from www.ijapc.com</ref>

The tissue metabolism corresponds to functions of dhatvagni at various levels as below:<ref>Amardeep Kour, Gupta Vikas, Sodhi Danisha. Importance of Nyayas on Body’s Well-Being – A Conceptual Study. Int J Ayu Pharm Chem 2015 Vol. 4 Issue 1.pg.95-106 available from www.ijapc.com</ref>

Rasa Dhatwagni: Glucose metabolism, circulation in portal vein, formation of WBC

Rasadhatwagni: Glucose metabolism, circulation in portal vein, formation of WBC

Raktadhatwagni:Hemopoeisis, iron metabolism, protein metabolism

Raktadhatwagni:Hemopoeisis, iron metabolism, protein metabolism

In some organs, such as the gut and bone marrow, stem cells regularly divide to repair and replace worn out or damaged tissues. In other organs, however, such as the pancreas and the heart, stem cells only divide under special conditions.<ref>Ghaffari S. Cancer, stem cells and cancer stem cells: Old ideas, new developments. F1000 Med Rep. 2011;3:23 </ref> Mesodermal progenitor cells are found throughout the body, they can differentiate to form multiple cell types (e.g. osteocytes, adipocytes, chondrocytes, fibroblasts, and smooth muscle cells) and they have a limited ability to self-renew.<ref>Melero-Martin JM, Dudley AC. Concise review: Vascular stem cells and tumor angiogenesis. Stem Cells. 2011;29:163–8 </ref>  

In some organs, such as the gut and bone marrow, stem cells regularly divide to repair and replace worn out or damaged tissues. In other organs, however, such as the pancreas and the heart, stem cells only divide under special conditions.<ref>Ghaffari S. Cancer, stem cells and cancer stem cells: Old ideas, new developments. F1000 Med Rep. 2011;3:23 </ref> Mesodermal progenitor cells are found throughout the body, they can differentiate to form multiple cell types (e.g. osteocytes, adipocytes, chondrocytes, fibroblasts, and smooth muscle cells) and they have a limited ability to self-renew.<ref>Melero-Martin JM, Dudley AC. Concise review: Vascular stem cells and tumor angiogenesis. Stem Cells. 2011;29:163–8 </ref>  

Rasa Dhatu may have all types of cell differentiate lineage responsible for the development of all saptadhatu, may be known as pluripotent.<ref>Sharma V, Chaudhary AK. Concepts of Dhatu Siddhanta (theory of tissues formation and differentiation) and Rasayana; probable predecessor of stem cell therapy. Ayu. 2014;35(3):231–236. doi:10.4103/0974-8520.153731 </ref>   

[[Rasa Dhatu]] may have all types of cell differentiate lineage responsible for the development of all saptadhatu, may be known as pluripotent.<ref>Sharma V, Chaudhary AK. Concepts of Dhatu Siddhanta (theory of tissues formation and differentiation) and Rasayana; probable predecessor of stem cell therapy. Ayu. 2014;35(3):231–236. doi:10.4103/0974-8520.153731 </ref>   

Recent studies suggest that the spermatogonial stem cells can be reprogrammed to become ES-like cells to acquire pluripotency.<ref>Singh SR, Burnicka-Turek O, Chauhan C, Hou SX. Spermatogonial stem cells, infertility and testicular cancer. J Cell Mol Med. 2011;3(15):468–83 </ref> Wholesome shukradhatu may be considered as pluripotent, because it is responsible for the transmission of genetic information from an individual to the next generation.  

Recent studies suggest that the spermatogonial stem cells can be reprogrammed to become ES-like cells to acquire pluripotency.<ref>Singh SR, Burnicka-Turek O, Chauhan C, Hou SX. Spermatogonial stem cells, infertility and testicular cancer. J Cell Mol Med. 2011;3(15):468–83 </ref> Wholesome shukradhatu may be considered as pluripotent, because it is responsible for the transmission of genetic information from an individual to the next generation.