Changes

==== Pathogenesis of various conditions ====

==== Pathogenesis of various conditions ====

All the verses explain a specific type of ''samprapti'' (pathogenesis) like ''koshthagata vata'' (''vata'' affecting alimentary tract), ''amashayagata vata'' (''vata'' affecting stomach.) etc. They are not to be considered as a single disease. These specific diseases may lead to many disease presentations in which the treatment strategies can be generalized. Any ''dosha'' may occupy any particular site or area and lead to diseases. This type of pathology of vitiated ''vata'' is called as ''gatavata''.  Normally in all ''gatavata'', the affected ''dushya''(vitiated body components) will be ''kshina'' (depleted) and affected ''srotas'' will be ''rikta'' (empty). The concept of ''gatavata'' can be further explored physiologically. ''Dhatu'' are classified into two types’ ''asthayi'' (temporary) ''dhatu'' and ''sthayi'' (permanent) ''dhatu''. ''Asthayi dhatu'' are the ones which are ''dravaswarupa'' (liquid state) and undergoing conversion (''parinam apadyamananam'') and they are being ''vikshepita'' (circulated) from their ''mulasthana'' (origin) throughout the ''sharira'' (''abhivahana'') for the purpose of ''poshana'' (nourishment) of the ''sthayi dhatu''. This ''parinamana'' (conversion) and ''abhivahana prakriya''(transportation) takes place in ''marga'' (channel) which are known as ''srotas''; hence ''marga'' is one of the synonym used for srotas alongwith sirā (vein), dhamani (artery), rasāyani (capillary), rasavāhini (channels carrying nutrient fluid), nādi (nerve), panthāna (pathway), sharir chhidra (perforated channel), samvrita-asamvritāni (covered or uncovered), sthāna (site), āshaya (organ), niketa (habitat), sharirdhātu avakāsha (hollow space in body tissues).

All the verses explain a specific type of ''samprapti'' (pathogenesis) like ''koshthagata vata'' (''vata'' affecting alimentary tract), ''amashayagata vata'' (''vata'' affecting stomach.) etc. They are not to be considered as a single disease. These specific diseases may lead to many disease presentations in which the treatment strategies can be generalized. Any ''dosha'' may occupy any particular site or area and lead to diseases. This type of pathology of vitiated ''vata'' is called as ''gatavata''.  Normally in all ''gatavata'', the affected ''dushya''(vitiated body components) will be ''kshina'' (depleted) and affected ''srotas'' will be ''rikta'' (empty). The concept of ''gatavata'' can be further explored physiologically. ''Dhatu'' are classified into two types’ ''asthayi'' (temporary) ''dhatu'' and ''sthayi'' (permanent) ''dhatu''. ''Asthayi dhatu'' are the ones which are ''dravaswarupa'' (liquid state) and undergoing conversion (''parinam apadyamananam'') and they are being ''vikshepita'' (circulated) from their ''mulasthana'' (origin) throughout the ''sharira'' (''abhivahana'') for the purpose of ''poshana'' (nourishment) of the ''sthayi dhatu''. This ''parinamana'' (conversion) and ''abhivahana prakriya''(transportation) takes place in ''marga'' (channel) which are known as ''srotas''; hence ''marga'' is one of the synonym used for ''srotas'' along with ''sira'' (vein), ''dhamani'' (artery), ''rasayani'' (capillary), ''rasavahini'' (channels carrying nutrient fluid), ''nadi'' (nerve), ''panthana'' (pathway), ''sharira chhidra'' (perforated channel), ''samvrita-asamvritani'' (covered or uncovered), ''sthana'' (site), ''ashaya'' (organ), ''niketa'' (habitat), ''shariradhatu avakasha'' (hollow space in body tissues).

 

''Prakupita''(vitiated) ''dosha'' have the capacity to further vitiate both ''sthanastha dhatu'' (fixed tissue element) as well as ''margagata'' (circulating tissue elements) ''sharira dhatu''. When ''prakupita vata'' vitiates the ''dhatu'', it is called as ''gatavata''. In this condition, vitiated ''vata'' affects the specific site due to specific etiological factors. While designing treatment protocol, in this context specific etiological factors for each and every ''gatavata'' related diseases must be observed to clarify why vitiated ''vata'' goes to specific part of the body or to specific ''dhatu'' to develop ''kosthagata vata, raktagata vāta'' etc. In this condition, ''dhatu'' is ''dushya'' (getting vitiated).

Koshthagata vata: Vāta getting vitiated in the kōṣṭha (elimentary tract) is explained as koshthagata vata.  

Koshthagata vata: Vāta getting vitiated in the kōṣṭha (elimentary tract) is explained as koshthagata vata.  

Gudagata vata: It can also be explained that gudagata vāta and pakvāśayagata vāta are different clinical entities. In gudagata vāta, obstruction of stool, urine and flatus is observed, whereas in pakvāśayagata vāta there ispainful defecation, micturition with āntrakujan (gurgling sound), ātopa (distension) and ānāha (constipation). Ashma sarkara (urolith) is exclusively present in gudagata vāta with pain and atrophy in calf muscles, thighs, sacram, feet and back. This can be compared with lumbo-sacral plexopathy. It may be understood as in case of pakvāśaya gatavāta, proximal part of large intestine alongwith ascending, transverse and descending colon is involved; whereas in gudagata vāta, involvement of sigmoid colon, rectum, anus and their nerve supply.

Gudagata vata: It can also be explained that gudagata vāta and pakvāśayagata vāta are different clinical entities. In gudagata vāta, obstruction of stool, urine and flatus is observed, whereas in pakvāśayagata vāta there ispainful defecation, micturition with āntrakujan (gurgling sound), ātopa (distension) and ānāha (constipation). Ashma sarkara (urolith) is exclusively present in gudagata vāta with pain and atrophy in calf muscles, thighs, sacram, feet and back. This can be compared with lumbo-sacral plexopathy. It may be understood as in case of pakvāśaya gatavāta, proximal part of large intestine alongwith ascending, transverse and descending colon is involved; whereas in gudagata vāta, involvement of sigmoid colon, rectum, anus and their nerve supply.