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<p style='text-align:justify;'>Roga marga means pathways of disease progression and manifestations. It is essential to know the path of progression and manifestation of the disease to plan the protocol for its management.  Roga marga is a place of vitiation of body channels (kha vaigunya). The disease can be cured, if the exact site of vitiation is targeted. Through the applicability of roga-marga, the recurrence of the disease may be reduced. [Cha.Sa.Chikitsa Sthana 15/36-37] The specific medicines for specific receptors can be developed. [Cha.Sa. Sutra Sthana 4/22]  <br/>Acharya Charaka has explained roga marga as under.<ref name="ref1">Agnivesha , Dridhbala , Charaka , Charaka Samhita , Sutrasthana , Taistraishaniya Adhyaya , 11/48 , reprinted 2020 , Chaukhamba Surbharati Prakashana , Varanasi , Page No. 77 </ref> [Cha.Sa.Sutrasthana 11/48]

<p style='text-align:justify;'>Roga marga means pathways of [[Vyadhi|disease]] progression and manifestations. It is essential to know the path of progression and manifestation of the [[Vyadhi|disease]] to plan the protocol for its management.  Roga marga is a place of vitiation of body channels (kha vaigunya). The disease can be cured, if the exact site of vitiation is targeted. Through the applicability of roga-marga, the recurrence of the disease may be reduced. [Cha.Sa.Chikitsa Sthana 15/36-37] The specific medicines for specific receptors can be developed. [Cha.Sa. Sutra Sthana 4/22]  <br/>Acharya Charaka has explained roga marga as under.<ref name="ref1">Agnivesha , Dridhbala , Charaka , Charaka Samhita , Sutrasthana , Taistraishaniya Adhyaya , 11/48 , reprinted 2020 , Chaukhamba Surbharati Prakashana , Varanasi , Page No. 77 </ref> [Cha.Sa.Sutrasthana 11/48]

# Three roga maragas viz. external (bahya), middle (madhyama) and  internal (abhyantara)   

# Three roga maragas viz. external (bahya), middle (madhyama) and  internal (abhyantara)   

# Each roga marga has set of structural / physiological entities.   

# Each roga marga has set of structural / physiological entities.