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Pharmaceutical preparation of ''vatsaka'' (Holarrhena antidysentrica Linn.Wall.) , its synonyms, and the difference between male and female plants (along with their pharmaceutical preparations) are described. The seeds of ''vatsaka'' are known as ''indrayava'' or ''kalingaka''. Fruits and seeds are used for therapeutic emesis. ''Vatsaka'' is used to treat ''raktapitta, kapha, vatarakta, visarpa'' and several other diseases. Total eighteen formulations are prepared in different medium like decoction of various drugs, water and ''krasara''. It is beneficial for delicate persons.

Pharmaceutical preparation of ''vatsaka'' (Holarrhena antidysentrica Linn.Wall.) , its synonyms, and the difference between male and female plants (along with their pharmaceutical preparations) are described. The seeds of ''vatsaka'' are known as ''indrayava'' or ''kalingaka''. Fruits and seeds are used for therapeutic emesis. ''Vatsaka'' is used to treat ''raktapitta, [[kapha]], vatarakta, visarpa'' and several other diseases. Total eighteen formulations are prepared in different medium like decoction of various drugs, water and ''krasara''. It is beneficial for delicate persons.

'''Keywords''': Indrayava, Decoction, Vatarakta, Visarpa. Holarrhena antidysentrica Linn.Wall.

'''Keywords''': Indrayava, Decoction, Vatarakta, Visarpa. Holarrhena antidysentrica Linn.Wall.

The male plant has big fruits, white flowers and smooth leaves while the female one is blackish, with reddish flowers and smaller fruits and their stalk.[5]

The male plant has big fruits, white flowers and smooth leaves while the female one is blackish, with reddish flowers and smaller fruits and their stalk.[5]

''Vatsaka'' destroys ''raktapitta'' and ''kapha'', is free from harmful effects and as such useful for the delicate persons. It is indicated in cardiac disorders, fever, ''vatarakta,'' erysipelas etc.[6]

''Vatsaka'' destroys ''raktapitta'' and [[kapha]], is free from harmful effects and as such useful for the delicate persons. It is indicated in cardiac disorders, fever, ''vatarakta,'' erysipelas etc.[6]

=== Various preparations ===

=== Various preparations ===

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The fruit (seeds) of both the types when mature and dry should be collected in proper time. They should be crushed in quantity as borne in closed fist (40 gm) and impregnated with the decoction of ''madhuka'' and ''kovidaradi'' drugs and kept there in for the whole night. In the next morning it should be pressed and added with salt and honey. [7-8]

The fruit (seeds) of both types when mature and dry should be collected in proper time. They should be crushed in quantity as borne in closed fist (40 gm) and impregnated with the decoction of ''madhuka'' and ''kovidaradi'' drugs and kept there in for the whole night. In the next morning it should be pressed and added with salt and honey. [7-8]

This excellent emetic should be taken to eliminate ''pitta'' and ''kapha''.[9]

This excellent emetic should be taken to eliminate [[pitta]] and [[kapha]].[9]

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=== Cause and effect ===

=== Cause and effect ===

It is useful in ''raktapitta'' due to ''sheeta veerya'' and pacifies the ''kapha'' due to ''laghu, ruksha guna; tikta, kashaya rasa'' and ''katu vipaka''.  

It is useful in ''raktapitta'' due to ''sheeta veerya'' and pacifies the [[kapha]] due to ''laghu, ruksha [[guna]]; tikta, kashaya rasa'' and ''katu vipaka''.  

The alkaloids in ''vatsaka'' have as powerful action as emetic in their immediate effect on the symptoms of intestinal amoebiasis as well as in their curative value, in such  doses as one grain daily by intramuscular injections.<ref>Indian Medicinal Plants, Vol.II, by K.R. Kirtikar and B.D. Basu, 1998, 1572.</ref>

The alkaloids in ''vatsaka'' have as powerful action as emetic in their immediate effect on the symptoms of intestinal amoebiasis as well as in their curative value, in such  doses as one grain daily by intramuscular injections.<ref>Indian Medicinal Plants, Vol.II, by K.R. Kirtikar and B.D. Basu, 1998, 1572.</ref>

In a research study (Chavan S.et.al., 2014), good improvement by observed by therapeutic emesis with ''vatsaka'' in patient of acne vulgaris. ''Indrayava churna'' in the quantity of 24 gm (''Antarnakhamushi''-closed fist) impregnated with the decoction of ''madhuka'' (Glycyrrhiza glabra Linn.) 160 ml kept there in for whole night. In the next morning it was be crushed and added with salt 10gm and honey 25 gm. The total quantity goes up to 219 ml approximately. The study concluded with following observations:

In a research study (Chavan S.et.al., 2014), good improvement by observed by therapeutic emesis with ''vatsaka'' in patient of acne vulgaris. ''Indrayava churna'' in the quantity of 24 gm (''Antarnakhamushi''-closed fist) impregnated with the decoction of ''madhuka'' (Glycyrrhiza glabra Linn.) 160 ml kept there in for whole night. In the next morning it was be crushed and added with salt 10gm and honey 25 gm. The total quantity goes up to 219 ml approximately. The study concluded with following observations:

*The average ''vega'' initiation time after giving ''indrayava kalpa'' was found to be 8 minutes. The average time for ''vamana'' reflex is 6 sec i.e. opening the mouth and completion of reflex.

*The average ''vega'' initiation time after giving ''indrayava kalpa'' was found to be 8 minutes. The average time for [[vamana]] reflex is 6 sec i.e. opening the mouth and completion of reflex.

*The mean ''vamaka'' dose of ''indrayava kalpa'' was found to be 718.67ml  

*The mean ''vamaka'' dose of ''indrayava kalpa'' was found to be 718.67ml  

*It is found to be highly significant with respect to ''sankhya'' (number of lesions), ''akara'' (size), ''varna'' (color), ''rija'' (pain), ''kandu'' (itching), ''daha'' (burning) and global acne grading score.<ref>15. Chavan Santosh (2014). Study of Vaman Karma in Indrayava Kalpa in Yuvan pidaka (Acne vulgaris). Thesis research work at Department of Panchakarma of Bharati Vidyapeeth Deemed University College of Ayurveda, Pune.</ref>

*It is found to be highly significant with respect to ''sankhya'' (number of lesions), ''akara'' (size), ''varna'' (color), ''rija'' (pain), ''kandu'' (itching), ''daha'' (burning) and global acne grading score.<ref>15. Chavan Santosh (2014). Study of Vaman Karma in Indrayava Kalpa in Yuvan pidaka (Acne vulgaris). Thesis research work at Department of Panchakarma of Bharati Vidyapeeth Deemed University College of Ayurveda, Pune.</ref>