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'''Keywords''': ''Shiroroga'' (diseases of head), ''hridaya roga''(diseases of heart), imbalances in ''dosha'', ''dhatu-kshaya'', ''mala-kshaya, pidaka, madhumeha, dosha-gati, sannipata, samsarga, ojokshaya, ojas,'' signs of depletion of ''dosha, dhatu'' and ''mala'', disorders of ''oja'', movement of ''dosha''.
 
'''Keywords''': ''Shiroroga'' (diseases of head), ''hridaya roga''(diseases of heart), imbalances in ''dosha'', ''dhatu-kshaya'', ''mala-kshaya, pidaka, madhumeha, dosha-gati, sannipata, samsarga, ojokshaya, ojas,'' signs of depletion of ''dosha, dhatu'' and ''mala'', disorders of ''oja'', movement of ''dosha''.
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Excessive exercising, fasting, worrying, fear, grief, taking dry, scanty and limited meals, dry beverages, exposure to wind and sun, insomnia, excessive excretion of mucus, blood, semen and excretions, adverse season or old age, major mental illness (''Bhuta-Upaghāta'') are the general causative factors for ''kshaya'' (depletion) of ''ojas'' [76-77]
 
Excessive exercising, fasting, worrying, fear, grief, taking dry, scanty and limited meals, dry beverages, exposure to wind and sun, insomnia, excessive excretion of mucus, blood, semen and excretions, adverse season or old age, major mental illness (''Bhuta-Upaghāta'') are the general causative factors for ''kshaya'' (depletion) of ''ojas'' [76-77]
 
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==== Etiological factors and pathogenesis of ''avrita madhumeha'' (diabetes due to obstructive pathogenesis) ===
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===Etiological factors and pathogenesis of ''avrita madhumeha'' (diabetes due to obstructive pathogenesis) ===
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गुरुस्निग्धाम्ललवणान्यतिमात्रं समश्नताम्|  
 
गुरुस्निग्धाम्ललवणान्यतिमात्रं समश्नताम्|  
 
नवमन्नं च पानं च निद्रामास्यासुखानि च||७८||  
 
नवमन्नं च पानं च निद्रामास्यासुखानि च||७८||