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<big>'''Abstract </big>'''

<big>'''Abstract </big>'''

 

''Rajayakshma'' is a syndrome consisting of diseases associated with wasting (''kshaya'') of various tissues including ''rasa'' and ''ojas'' causing immunodeficiency resulting in opportunistic infections, most common being tuberculosis. The term ''rajayakshma'' has been used interchangeably with tuberculosis. It is potentially fatal wasting disease that "consumes" the body.  This chapter describes etio-pathogenesis, signs and symptoms and principles of management. Groups of signs viz. a group of three signs, six signs and eleven signs are enlisted to designate variety of ''srotasa'' (systems) involved with increasing severity of disease. The complications and prognosis are elaborated to categorize the disease as one of the dreadful diseases. Treatment with modern antitubercular medicines reduces mortality in patients with tuberculosis (cure rate 11.42% and the death rate 40.9%) but when combined with Ayurvedic treatment there was significant improvement (cure rate 41.3% and the death rate 3.8%).  

''Rajayakshma'' is a syndrome consisting of diseases associated with wasting (''kshaya'') of various tissues including ''rasa'' and ''ojas'' causing immunodeficiency resulting in opportunistic infections, most common being tuberculosis. The term ''rajayakshma'' has been used interchangeably with tuberculosis. It is potentially fatal wasting disease that "consumes" the body.  This chapter describes etio-pathogenesis, signs and symptoms and principles of management. Groups of signs viz. a group of three signs, six signs and eleven signs are enlisted to designate variety of ''srotasa'' (systems) involved with increasing severity of disease. The complications and prognosis are elaborated to categorize the disease as one of the dreadful diseases. Treatment with modern antitubercular medicines reduces mortality in patients with tuberculosis (cure rate 11.42% and the death rate 40.9%) but when combined with Ayurvedic treatment there was significant improvement (cure rate 41.3% and the death rate 3.8%).  

'''Keywords''': ''Rajayakshma, kshaya, shosha,'' tuberculosis, ''vyadhikshamatva, dhatukshaya,'' immunity, depletion of tissues, wasting diseases.

'''Keywords''': ''Rajayakshma, kshaya, shosha,'' tuberculosis, ''vyadhikshamatva, dhatukshaya,'' immunity, depletion of tissues, wasting diseases. </div>

{{Infobox

{{Infobox

== Introduction ==

== Introduction ==

''Rajayakshma'' has been identified since Vedic period (2400 BC). ''Yakshma'',the word, first appeared in the vedas (Rigveda and Atharvaveda), but a detailed description was missing. In the Ayurvedic treatises, or the Samhitas (1000 BC to 500 AD), a detailed description of ''rajayakshma'' can be found. An account of its definition, etiology, pathogenesis, general features, management, and the prognosis is found in [[Charak Samhita]], ''Sushruta Samhita'', and ''Ashtanga Hridaya'' with more extensive description is in [[Charak Samhita]]. Four etiological factors are described, ''sahasa'' (over exertion or working beyond one's capacity), ''samdharana'' (suppression of natural urges), ''kshaya'' (depletion of tissue element) and ''vishamashana'' (irregular diet).  

''Rajayakshma'' has been identified since Vedic period (2400 BC). ''Yakshma'',the word, first appeared in the vedas (Rigveda and Atharvaveda), but a detailed description was missing. In the Ayurvedic treatises, or the Samhitas (1000 BC to 500 AD), a detailed description of ''rajayakshma'' can be found. An account of its definition, etiology, pathogenesis, general features, management, and the prognosis is found in [[Charak Samhita]], ''Sushruta Samhita'', and ''Ashtanga Hridaya'' with more extensive description is in [[Charak Samhita]]. Four etiological factors are described, ''sahasa'' (over exertion or working beyond one's capacity), ''samdharana'' (suppression of natural urges), ''kshaya'' (depletion of tissue element) and ''vishamashana'' (irregular diet).  

#Shailaja C. Journal of Health & Population in Developing Countries. Vol. 3. WHO publication; 2000.A few research outcomes relevant for Public Health from Indian System of Medicine; p. 109.

#Shailaja C. Journal of Health & Population in Developing Countries. Vol. 3. WHO publication; 2000.A few research outcomes relevant for Public Health from Indian System of Medicine; p. 109.

#Singh, RH and Rastogi, S. Rasayana Therapy and Rejuvenation. In Evidence based practice of CAM,  PP 177-190. Springer, Germany. 2012

#Singh, RH and Rastogi, S. Rasayana Therapy and Rejuvenation. In Evidence based practice of CAM,  PP 177-190. Springer, Germany. 2012

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