Changes

In some organs, such as the gut and bone marrow, stem cells regularly divide to repair and replace worn out or damaged tissues. In other organs, however, such as the pancreas and the heart, stem cells only divide under special conditions.<ref>Ghaffari S. Cancer, stem cells and cancer stem cells: Old ideas, new developments. F1000 Med Rep. 2011;3:23 </ref> Mesodermal progenitor cells are found throughout the body, they can differentiate to form multiple cell types (e.g. osteocytes, adipocytes, chondrocytes, fibroblasts, and smooth muscle cells) and they have a limited ability to self-renew.<ref>Melero-Martin JM, Dudley AC. Concise review: Vascular stem cells and tumor angiogenesis. Stem Cells. 2011;29:163–8 </ref>  

In some organs, such as the gut and bone marrow, stem cells regularly divide to repair and replace worn out or damaged tissues. In other organs, however, such as the pancreas and the heart, stem cells only divide under special conditions.<ref>Ghaffari S. Cancer, stem cells and cancer stem cells: Old ideas, new developments. F1000 Med Rep. 2011;3:23 </ref> Mesodermal progenitor cells are found throughout the body, they can differentiate to form multiple cell types (e.g. osteocytes, adipocytes, chondrocytes, fibroblasts, and smooth muscle cells) and they have a limited ability to self-renew.<ref>Melero-Martin JM, Dudley AC. Concise review: Vascular stem cells and tumor angiogenesis. Stem Cells. 2011;29:163–8 </ref>  

[[Rasa Dhatu]] may have all types of cell differentiate lineage responsible for the development of all saptadhatu, may be known as pluripotent.<ref>Sharma V, Chaudhary AK. Concepts of Dhatu Siddhanta (theory of tissues formation and differentiation) and Rasayana; probable predecessor of stem cell therapy. Ayu. 2014;35(3):231–236. doi:10.4103/0974-8520.153731 </ref>   

[[Rasa Dhatu]] may have all types of cell differentiate lineage responsible for the development of all saptadhatu, may be known as pluripotent.<ref name=SharmaV2014>Sharma V, Chaudhary AK. Concepts of Dhatu Siddhanta (theory of tissues formation and differentiation) and Rasayana; probable predecessor of stem cell therapy. Ayu. 2014;35(3):231–236. doi:10.4103/0974-8520.153731 </ref>   

Recent studies suggest that the spermatogonial stem cells can be reprogrammed to become ES-like cells to acquire pluripotency.<ref>Singh SR, Burnicka-Turek O, Chauhan C, Hou SX. Spermatogonial stem cells, infertility and testicular cancer. J Cell Mol Med. 2011;3(15):468–83 </ref> Wholesome shukradhatu may be considered as pluripotent, because it is responsible for the transmission of genetic information from an individual to the next generation.  

Recent studies suggest that the spermatogonial stem cells can be reprogrammed to become ES-like cells to acquire pluripotency.<ref>Singh SR, Burnicka-Turek O, Chauhan C, Hou SX. Spermatogonial stem cells, infertility and testicular cancer. J Cell Mol Med. 2011;3(15):468–83 </ref> Wholesome shukradhatu may be considered as pluripotent, because it is responsible for the transmission of genetic information from an individual to the next generation.  

Thus, each dhatu carry the potency to regenerate further dhatu, because each avayava (organ) is formed by composition of many dhatus.<ref>Sharma V, Chaudhary AK. Concepts of Dhatu Siddhanta (theory of tissues formation and differentiation) and Rasayana; probable predecessor of stem cell therapy. Ayu. 2014;35(3):231–236. doi:10.4103/0974-8520.153731 </ref>  

Thus, each dhatu carry the potency to regenerate further dhatu, because each avayava (organ) is formed by composition of many dhatus.<ref name=SharmaV2014 />  

===List of thesis done===

===List of thesis done===

1. Upadhyay Vashudev J (2001) :Medo-Dhatvagni ka Sthaulya Roga ke Sandharbha mein Saidhantika evam Prayogika Adhyayana, Department of Basic principles, IPGT&RA,Jamnagar.

1. Upadhyay Vashudev J (2001) :Medo-Dhatvagni ka Sthaulya Roga ke Sandharbha mein Saidhantika evam Prayogika Adhyayana, Department of Basic principles, IPGT&RA,Jamnagar.