Changes

==== Herbs used For ''Shirovirechana''(catharsis of cephalic region) ====

==== Herbs used For ''Shirovirechana''(catharsis of cephalic region) ====

The drug ''Apamarga'' (Achyranthes aspera Linn.) is considered to be the potential drug to eliminate vitiating factors from head. [Ca.Su.25/40] ''Surasa'' (Ocimum sanctum Linn.), ''Shweta Surasa'' (Ocimum sanctum Linn.), ''Phanijjaka'' (Origanum majorana), ''Kutheraka'' (Ocimum canum) are the drugs of ''Surasadi gana''. [Su.Su.38], and are said to be ''krimighna'' (antimicrobial) and ''kaphaghna'' (which alleviate phlegm). Chakrapanidatta terms ''Ajagandha'' as ''Ajamoda'' (Apium graveolens Linn.). The reference of ''krimi''(microbe) in the context of those invading the head and not of the body.[ ]    [ verse 1-6]

The drug ''Apamarga'' (Achyranthes aspera Linn.) is considered to be the potential drug to eliminate vitiating factors from head. [Ca.Su.25/40] ''Surasa'' (Ocimum sanctum Linn.), ''Shweta Surasa'' (Ocimum sanctum Linn.), ''Phanijjaka'' (Origanum majorana), ''Kutheraka'' (Ocimum canum) are the drugs of ''Surasadi gana''. [Su.Su.38], and are said to be ''krimighna'' (antimicrobial) and ''kaphaghna'' (which alleviate phlegm). Chakrapanidatta terms ''Ajagandha'' as ''Ajamoda'' (Apium graveolens Linn.). The reference of ''krimi''(microbe) in the context of those invading the head and not of the body.<ref>

www.iamj.in/posts/images/upload/298_303.pdfnopr.niscair.res.in/bitstream/123456789/.../IJTK%208(3)%20372-378.pdftheglobaljournals.com/gra/file.php?val=September_2014...42.pdf </ref>[ ]    [ verse 1-6]

==== Herbs used in therapeutic emesis ====

==== Herbs used in therapeutic emesis ====

These refer to the plants used for emesis for a disease that originates from the site of ''kapha''; the upper portion of ''amashaya'' (stomach). ''Pitta'' vitiation may not require emesis, but when this aggravated ''pitta'' reaches the site of ''kapha'', then it is to be eliminated through emesis. Different sites or parts of the body are associated with different ''dosha''. So when a vitiated ''dosha'' leaves its own “site” and occupies the site of another ''dosha'', then it is to be treated on the lines of treatment for the latter. [Ca.Ci.3/142] Among all plants enumerated for emesis ''Madnaphala'' (Catunaregam spinosa ) is considered important owing to its lesser side effects[Ca.Ka.1/13]  and its strong effect. [Ca.Su.25/40].  

These refer to the plants used for emesis for a disease that originates from the site of ''kapha''; the upper portion of ''amashaya'' (stomach). ''Pitta'' vitiation may not require emesis, but when this aggravated ''pitta'' reaches the site of ''kapha'', then it is to be eliminated through emesis. Different sites or parts of the body are associated with different ''dosha''. So when a vitiated ''dosha'' leaves its own “site” and occupies the site of another ''dosha'', then it is to be treated on the lines of treatment for the latter. [Ca.Ci.3/142] Among all plants enumerated for emesis ''Madnaphala'' (Catunaregam spinosa ) is considered important owing to its lesser side effects[Ca.Ka.1/13]  and its strong effect. [Ca.Su.25/40].  

Therefore, it is widely used in clinical practice. Apart from ''Madanaphala'', five other drugs, and in total 355 formulations are described; One of these formulations is ''Kritavedhana'' (Luffa acutangula) ''kalpa'' (formulations). It is specially indicated to be effective for treating cases of ''kushtha'' (skin diseases), ''garavisha'' (slow poison) etc for therapeutic emesis.[ ]  [verse 7-8]

Therefore, it is widely used in clinical practice. Apart from ''Madanaphala'', five other drugs, and in total 355 formulations are described; One of these formulations is ''Kritavedhana'' (Luffa acutangula) ''kalpa'' (formulations). It is specially indicated to be effective for treating cases of ''kushtha'' (skin diseases), ''garavisha'' (slow poison) etc for therapeutic emesis.<ref> www.ncbi.nlm.nih.gov › NCBI › Literature › PubMed Central (PMC)jpsionline.com/admin/php/uploads/110_pdf.pdf </ref>[ ]  [verse 7-8]

==== Herbs for ''virechana'' [therapeutic purgation] ====

==== Herbs for ''virechana'' [therapeutic purgation] ====

Evacuation of the fecal matter and other accumulated ''dosha''(vitiated factors) in the lower gastrointestinal tract through the anal route is known as ''virechana karma''(Ch. Ka.1/4). Among the three ''dosha'' the morbid accumulation of ''pitta dosha'' is best eliminated by this procedure. Abnormal accumulation of ''kapha dosha'' in the lower gastro-intestinal tract or ''pitta sthana'' (place) is also treated by the ''virechana karma''. This also includes treatment of vitiated ''dosha'' of the stomach, small intestine, liver and gall bladder, as well as a method of bringing them to the gastro-intestinal tract for their eventual expulsion from the body through rectum. This process not only eradicates the diseases of ''pitta'' and blood, but also it helps in rejuvenating all the tissues and organs in the abdomen, improving skin complexion, imparting longevity and increasing immunity.[Ca.Su.15/23; Su.Ci.33/18](Cha. Su. 15/23; Su. Chi. 33/18).

Evacuation of the fecal matter and other accumulated ''dosha''(vitiated factors) in the lower gastrointestinal tract through the anal route is known as ''virechana karma''(Ch. Ka.1/4). Among the three ''dosha'' the morbid accumulation of ''pitta dosha'' is best eliminated by this procedure. Abnormal accumulation of ''kapha dosha'' in the lower gastro-intestinal tract or ''pitta sthana'' (place) is also treated by the ''virechana karma''. This also includes treatment of vitiated ''dosha'' of the stomach, small intestine, liver and gall bladder, as well as a method of bringing them to the gastro-intestinal tract for their eventual expulsion from the body through rectum. This process not only eradicates the diseases of ''pitta'' and blood, but also it helps in rejuvenating all the tissues and organs in the abdomen, improving skin complexion, imparting longevity and increasing immunity.[Ca.Su.15/23; Su.Ci.33/18](Cha. Su. 15/23; Su. Chi. 33/18).

The selection of medicines for purgation depends upon, softness or hardness of bowel movements and constitution of the patient. Among the plants for purgation, ''Trivrit'' (Operculina turpethum) is considered the best because it causes comfortable evacuation. [Ca.Su.25/40].[ ]  

The selection of medicines for purgation depends upon, softness or hardness of bowel movements and constitution of the patient. Among the plants for purgation, ''Trivrit'' (Operculina turpethum) is considered the best because it causes comfortable evacuation. [Ca.Su.25/40].<ref> www.ijpbs.net/issue-4/Ph-53.pdf </ref>[ ]  

Operculina turpethum has anthraquinone glycoside also known as emodin. Unabsorbed in the small intestine, they are passed to the colon where bacteria liberates the active form, which either acts locally or is absorbed into circulation and gets excreted in bile to act on small intestine. The active principle is believed to work on myenteric plexus to increase peristalsis and decrease segmentation.

Operculina turpethum has anthraquinone glycoside also known as emodin. Unabsorbed in the small intestine, they are passed to the colon where bacteria liberates the active form, which either acts locally or is absorbed into circulation and gets excreted in bile to act on small intestine. The active principle is believed to work on myenteric plexus to increase peristalsis and decrease segmentation.

Cassia fistula’s laxative action comes from a group of well documented compounds called anthraquinones that are found in all cassia and senna plants in varying degrees.

Cassia fistula’s laxative action comes from a group of well documented compounds called anthraquinones that are found in all cassia and senna plants in varying degrees.

''Eranda'' (Ricinus communis) is used widely as purgative. It mainly contains triglyceride of ricinoleic acid which is a polar long chain fatty acid. It is hydrolysed in the ileum by lipase to ricinoleic acid and glycerol. It is believed to irritate the mucosa and stimulate intestinal contractions. [ ] [ verse 9-10]

''Eranda'' (Ricinus communis) is used widely as purgative. It mainly contains triglyceride of ricinoleic acid which is a polar long chain fatty acid. It is hydrolysed in the ileum by lipase to ricinoleic acid and glycerol. It is believed to irritate the mucosa and stimulate intestinal contractions.<ref> florajournal.com/vol1issue3/aug2013/21.1.pdf </ref> [ ] [ verse 9-10]

==== Herbs used in enema ====  

==== Herbs used in enema ====  

Likewise, the enema administered predominantly containing ''sneha'' (oil) is known as ''anuvasana basti''. Among these two types of enema, ''niruha'' (decoction enema) is considered superior to ''anuvasana'' (oil enema) because it is more effective in the elimination of vitiated factors. Details about these drugs have been mentioned in [[Vimana Sthana]] (Cha. Vi. 8/ 138-144).   

Likewise, the enema administered predominantly containing ''sneha'' (oil) is known as ''anuvasana basti''. Among these two types of enema, ''niruha'' (decoction enema) is considered superior to ''anuvasana'' (oil enema) because it is more effective in the elimination of vitiated factors. Details about these drugs have been mentioned in [[Vimana Sthana]] (Cha. Vi. 8/ 138-144).   

The pharmacodynamics of systemic effect of ''basti'' (enema) may be understood through the absorption mechanism, concept of systems biology, neural stimulation mechanism, and excretory mechanism. As it is a homogenous emulsion mixture of honey, ''saindhava'' (salt), ''sneha dravya'' (oil/unctuous material), ''kalka'' (paste of drugs), and decoction of crude drugs which is given through rectum. Through rectal route large quantity of drugs can be delivered for systemic circulation. The concept of systems biology is that a change at cellular level can bring changes in tissues, organs and consequently in the whole body. As per recent advancements in medicine, the intestine not only is a highly vascular organ, but is also a highly innervated organ that forms an "enteric nervous system" (ENS). ENS may work synergistically with the central nervous system of body. The cleansing action of ''basti'' (enema) is related to the facilitation of excretion of morbid substances responsible for the disease process into the colon, from where it is evacuated. [ ]  

The pharmacodynamics of systemic effect of ''basti'' (enema) may be understood through the absorption mechanism, concept of systems biology, neural stimulation mechanism, and excretory mechanism. As it is a homogenous emulsion mixture of honey, ''saindhava'' (salt), ''sneha dravya'' (oil/unctuous material), ''kalka'' (paste of drugs), and decoction of crude drugs which is given through rectum. Through rectal route large quantity of drugs can be delivered for systemic circulation. The concept of systems biology is that a change at cellular level can bring changes in tissues, organs and consequently in the whole body. As per recent advancements in medicine, the intestine not only is a highly vascular organ, but is also a highly innervated organ that forms an "enteric nervous system" (ENS). ENS may work synergistically with the central nervous system of body. The cleansing action of ''basti'' (enema) is related to the facilitation of excretion of morbid substances responsible for the disease process into the colon, from where it is evacuated.<ref> www.ijpba.info/ijpba/index.php/ijpba/article/viewFile/758/519 </ref> [ ]  

[verse 11-14]

[verse 11-14]

===== Chart 2: Types of ''Yavagu'' =====

===== Chart 2: Types of ''Yavagu'' =====

[[File:yavaguit.png]]

[[File:yavaguit.png]]

=== Further reading and reference books ===

=== Further reading and reference books ===