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+#REDIRECT [[Vajikarana Adhyaya]]
-|title=Vajikarana
-|titlemode=append
-|keywords=carakasamhitaonline, charak samhita, caraka samhita, ayurveda, Vajikarana, aphrodisiac therapy, Vajikarana meaning, Vajikarana therapy,  indian systems of medcine, natural medicine, therapy
-|description=Vajikarana is a therapy that increases the virility
-|image=http://www.carakasamhitaonline.com/resources/assets/ogimgs.jpg
-|image_alt=carak samhita
-|type=article
-}}
-<div style='text-align:justify;'>
-The term ‘Vajikarana’ (also spelled as vajeekarana) is a combination of two Sanskrit words: vaji and karana. ‘Vaji’ means ‘horse’ [Vachaspatya] and ‘karana’ means ‘to do/make/effect/cause’.<ref>Monier-Williams, Monier-Williams Sanskrit- English Dictionary, 1st edition; Oxford University Press, vaji, Page 254.</ref> The term ‘vajikara’ means strengthening, stimulating or producing virility.<ref>Monier-Williams, Monier-Williams Sanskrit- English Dictionary, 1st edition; Oxford University Press, vajikara, Page 938.</ref>  The therapy to increase virility like a horse is called vajikarana. [Cha.Sa.[[Chikitsa Sthana]] 2/4/51] Since ancient times, a horse is considered a symbol of sexuality and strength. Therefore, the name of therapy symbolizes making a person virile and potent like a horse. It is one of the eight specialties of Ayurveda. [Cha.Sa.[[Sutra Sthana]] 30/28] This therapy is aimed to promote overall health with a specific focus on sexual and reproductive health. It is preventive therapy [Cha.Sa.[[Chikitsa Sthana]] 1/1/3-5] as well as curative therapy for various sexual disorders. In current practices, aphrodisiac therapy, sexual vigor enhancing tonics, and treatment are considered as forms of vajikarana therapy. Ayurveda advises purification procedures before administration of vajikarana therapy. It is intended to improve the quality of reproductive elements like [[shukra dhatu]] and healthy progeny.
-{{Infobox
-|title =  Contributors
-|label1 = Section/Chapter
-|data1 = [[Chikitsa]] / [[Vajikarana]]
-|label2 = Authors
-|data2 = Aneesh E.G., Deole Y.S.
-|label3 = Reviewed by
-|data3 = Basisht G.
-|label4 = Affiliations
-|data4 = [[Charak Samhita Research, Training and Development Centre]], I..T.R.A., Jamnagar
-|label5 = Correspondence email:
-|data5 = carakasamhita@gmail.com
-|label6 = Date of publication
-|data6 = May 20, 2021
-|label7 = DOI
-|data7 =  Awaited
-}}
-==Importance==
-===In the preservation of health and prevention===
-Vajikarana therapy is an important measure to preserve and promote health in healthy individuals. [Cha.Sa.[[Chikitsa Sthana]] 1/1/13]  This therapy is advised to restore tissue equilibrium and prevent recurrence after the treatment of diseases. [Cha.Sa.[[Sutra Sthana]] 7/48-49]
-===In the management of disease===
-Vajikarana therapy is usually applied in the treatment of diseases due to the vitiation of the reproductive system ([[shukra dhatu]]). Diseases of male reproductive system like impotency [Cha.Sa.[[Chikitsa Sthana]] 30/193], premature ejaculation, erectile dysfunction are treated with this therapy.[Cha.Sa.[[Chikitsa Sthana]] 30/146] Vajikarana leads to the nourishment of the body. [A.S.Sutra Sthana 24/19]<ref name= Sangraha> Vridha Vagbhata, Ashtanga Sangraha. Edited by Shivaprasad Sharma. 3rd ed. Varanasi: Chaukhamba sanskrit series office;2012.</ref> Therefore, this therapy is used in the management of degenerative diseases and rehabilitation therapies in disorders caused by depletion of body tissues. The therapy is also used to improve mood and mental strength in psychiatric diseases.
-==Benefits==
-Vajikarana therapy leads to quick sexual stimulation and increases sexual vigor for a longer duration. In long-term therapy, it improves the quality and quantity of reproductive elements. It is effective in improving overall sexual health, fertility, and healthy progeny. Sexual vigor can be maintained even at old age.  [Cha.Sa.[[Chikitsa Sthana]] 1/1/9-12]
-This article deals with the concept and practices of vajikarana therapy in Ayurveda and contemporary views.
-==Principles of vajikarana therapy==
-The vajikarana therapy is based on the following principles:
-#Nourishment (apyayana): Vajikarana therapy nourishes the [[shukra dhatu]] to improve its quality and quantity.
-#Clearing and soothing effect (prasadana): Vajikarana pacifies [[dosha]] affecting [[shukra dhatu]] and improves its quality.
-#Increasing (upachaya): It increases the production of [[shukra dhatu]] in a middle-aged person.
-#Genesis (shukrajanana): It promotes genesis of [[shukra dhatu]] even if the quantity is deficient, as seen in old age.[Dalhana on Su.Sa.Sutra Sthana 1/8]<ref name=Susruta/>
-==Indications==
-In healthy, Vajikarana is indicated in person desiring for healthy progeny and to promote sexual health.
-In disease, Vajikarana is indicated in emaciation due to excess sexual intercourse, impotency, infertility and sexual disorders. [Su.Sa.Chikitsa Sthana 26/3]<ref name= Susruta> Sushruta. Sushruta Samhita. Edited by Jadavaji Trikamji Aacharya. 8th ed. Varanasi: Chaukhambha Orientalia;2005.</ref>
-==Prerequisite for vajikarana therapy==
-Purification therapies must be done before vajikarana therapy. It is essential to remove toxins and clear body channels to achieve the optimum benefit of vajikarana therapy. [Cha.Sa.[[Chikitsa Sthana]] 2/1/50-51] The purification can be done by administration of decoction and unctuous enema ([[basti]]). [Cha.Sa.[[Chikitsa Sthana]] 2/4/9]
-==Properties==
-The substance used for vajikarana therapy should possess the following properties:
-*Sweet (madhura)
-*Unctuous (snigdha)
-*Life promoting (jivanam)
-*Nourishing (brimhana)
-*Heavy to digest (guru)
-*Elevating mood and happiness (mano harshana) [Cha.Sa.[[Chikitsa Sthana]] 2/4/36]
-*Increases strength [A.S. Uttara Sthana 50/64]<ref name=Sangraha/>
-==Methods of vajikarana therapy==
-Vajikarana is administered through the following means:
-#Diet
-#Daily habits
-#Psychological factors
-#Therapeutic measures
-===Diet===
-Following food items are helpful to improve the quality and quantity of [[shukra dhatu]].
-*Daily consumption of ghee and milk. [Cha.Sa.[[Chikitsa Sthana]] 2/3/20]
-*Habitual use of diet consisting of equal parts of ghee and roasted corn flour [Cha.Sa.[[Sutra Sthana]] 25/40]
-*Milk [Cha.Sa.[[Sutra Sthana]] 1/107]
-*Honey [Su.Sa.Sutra Sthana 45/132]<ref name=Susruta/>
-*Coconut water [A.S.Sutra Sthana 6/23]<ref name=Sangraha/>
-*Sugarcane juice[A.S.Sutra Sthana 6/49]<ref name=Sangraha/>
-*Crude sugar, sugar candy and white fine sugar[A.S.Sutra Sthana 6/55]<ref name=Sangraha/>
-*Barley (yava) [A.S.Sutra Sthana 7/10]<ref name=Sangraha/>
-*Wheat [A.S.Sutra Sthana 7/11]<ref name=Sangraha/>
-*Shashtika rice (a rice variety) along with milk, ghee, sugar and honey [Cha.Sa.[[Chikitsa Sthana]] 2/2/27]
-*Powder of Glycyrrhiza glabra (yashtimadhu) with ghee and honey followed by milk [Cha.Sa.[[Chikitsa Sthana]] 2/3/18-19]
-*Meat soup[A.S.Sutra Sthana 7/33]<ref name=Sangraha/>, meat of rooster [A.S.Sutra Sthana 7/77]<ref name=Sangraha/>, kulira (a fish variety) - [A.S.Sutra Sthana 7/91]<ref name=Sangraha/>
-*Bone marrow and animal fat [Cha.Sa.[[Sutra Sthana]] 27/295]
-===Regimens with aphrodisiac (vajikarana) effect===
-*Bath [Cha.Sa.[[Sutra Sthana]] 5/94],
-*Comfortable sitting and proper sleep  [Su.Sa.Chikitsa Sthana 24/81]<ref name=Susruta/>
-===Mental factors===
-*Affectionate and loving conversation, touch, and pleasant music [Su.Sa.Chikitsa Sthana 26/6]<ref name=Susruta/>
-*A loving and pleasant companion is the best to increase virility.[Cha.Sa.[[Chikitsa Sthana]] 2/1/4]
-===Therapies===
-Decoction enema [A.S. Sutra Sthana 28/5]<ref name=Sangraha/>, unctuous enema processed with vajikarana medicines (vrishyabasti) [A.S.Kalpa Sthana 5/11]<ref name=Sangraha/> and gentle massage (samvahana) [Su.Sa.Chikitsa Sthana 24/83]<ref name=Susruta/> increases virility.
-'''Herbs and medicines:'''
-The herbs that increase the amount of semen are Withania somnifera (ashwagandha), Asparagus adscendens (musali), sugar (sharkara) and Asparagus racemosus (shatavari). [Sha.Purvakhanda.4/15]<ref name= Shargadara> Sharangadhara. Sharangadhara Samhita. Translated from Sanskrit by K.R. Srikantha Murthy. Reprint ed. Varanasi: Chaukhambha orientalia;2016.</ref>
-The drugs which initiate proper functioning of semen are milk, black gram (masha), fruit pulp of Semicarpus anacardium (bhallataka phalamajja), and Phyllanthus embilica (amalaki). [Sha.Purvakhanda.4/16]<ref name=Shargadara/>
-Solanum americanum (kakamachi) [A.S.Sutra Sthana 7/103]<ref name=Sangraha/>, Pueraria tuberose (vidari) [A.S.Sutra Sthana 7/120]<ref name=Sangraha/>, Benincasa hispida (kushmanda) [A.S.Sutra Sthana 7/124]<ref name=Sangraha/>, grape [A.S.Sutra Sthana 7/154]<ref name=Sangraha/>, dry ginger[A.S.Sutra Sthana 12/30]<ref name=Sangraha/>, ginger [Cha.Sa.[[Sutra Sthana]] 27/296], Sida cordifolia (bala), Abutilon indicum (atibala), Sida cordata (nagabala) [A.S.Sutra Sthana 12/43]<ref name=Sangraha/>, black gram [Cha.Sa.[[Sutra Sthana]] 27/24],  Phoenix sylvestris Roxb.(dates) [Cha.Sa.[[Sutra Sthana]] 27/127], Mucuna pruriens (kapikacchu) [Sha.Purvakhanda.4/14]<ref name=Shargadara/> etc. are some of the drugs which promotes virility.
-==Diets contraindicated in vajikarana therapy==
-Following food items negatively affect virility and contraindicated during vajikarana therapy:
-*All types of salts except rock salt [A.S. Sutra Sthana 18/17]<ref name=Sangraha/> [A.S. Sutra Sthana 12/17]<ref name=Sangraha/>
-*Buttermilk [Su.Sa.Sutra Sthana 45/84]<ref name=Susruta/>
-*Bitter and spicy food items [Cha.Sa.[[Sutra Sthana]] 27/4] [Cha.Sa.[[Sutra Sthana]] 26/51]
-*If food is taken in less quantity than required [Cha.Sa.[[Vimana Sthana]] 2/7]
-==Time of administration==
-Vajikarana medicines should be used along with morsel of food (sagrasa). [A.S. Sutra Sthana 23/22]<ref name=Sangraha/>
-Detail list of food and formulations is described in [[vajikarana Adhyaya]] chapter of [[Charak Samhita]].
-==Contemporary views==
-In modern medical systems, drugs to increase sex hormones are used. Commonly phenethylamines, synthetic testosterone are used to increase libido and treat sexual dysfunctions.
-The diet, regimen, medicine, and therapies that stimulate spermatogenesis, improve sperm count, decrease spermatic defects, improve sexual desire, vigor, duration of intercourse can be considered as forms of vajikarana therapy.
-==Current researches==
-Research studies are carried out on role of herbs on increasing sexual desire and aphrodisiac effect. This is elaborately discussed in the chapter of Vajikarana of Charak Samhita. Some notes are provided additionally in this article.
-===Anti-oxidants===
-Reactive oxygen species (ROS) cause oxidative stress leading to idiopathic male infertility and sexual dysfunction. The oxidative stress may also lead to sperm DNA damage which has negative impact over reproductive outcome. By reducing oxidative stress, the natural antioxidants significantly increase sperm motility and sperm counts in infertile men. Mucuna pruriens (kapikacchu), Tribulus terrestris (gokshura) and Withania somnifera (ashwagandha)  enhance the sexual function by increasing testosterone levels and regulating nuclear factor-kB (NF-kB) and nuclear factor erythroid 2 related factor (Nrf2) signaling pathways. It also decreases the ROS levels.<ref name=sahink>Sahin K, Tuzcu M, Orhan C, Gencoglu H, Sahin N, Akdemir F, Turk G, Yilmaz I, Juturu V. MAT, a Novel Polyherbal Aphrodisiac Formulation, Enhances Sexual Function and Nrf2/HO-1 Pathway While Reducing Oxidative Damage in Male Rats. Evid Based Complement Alternat Med. 2018 Apr 29;2018:8521782. doi: 10.1155/2018/8521782. PMID: 29853975; PMCID: PMC5949178.</ref>
-In an experimental study, Mucuna pruriens (kapikacchu), Tribulus terrestris (gokshura) and Withania somnifera (ashwagandha) combination showed increase in weight of seminal vesicles and ventral prostate of rats. The sperm motility and sperm counts were also increased by 30 -40% than the control group. FSH, LH, and testosterone levels were also improved. Lowest levels of serum and testicular tissue malondialdehyde (MDA) were found in trial group. MDA is an end product of ROS mediated lipid peroxidation. NF-kB levels were also found to be lowest in the group treated with the above medicines.<ref name=sahink/>
-Withania somnifera (ashwagandha) is found effective in stress-induced sexual disorders in rat models. It produces a gamma aminobutyric acid (GABA) like effect and prevents the overstimulation of nerve cells. It reduces the cortisol levels to bring calming effect.<ref name=mamidi>Mamidi P, Thakar AB. Efficacy of Ashwagandha (Withania somnifera Dunal. Linn.) in the management of psychogenic erectile dysfunction. Ayu. 2011 Jul;32(3):322-8. doi: 10.4103/0974-8520.93907. PMID: 22529644; PMCID: PMC3326875.</ref>
-===Effect of therapeutic purgation ([[virechana]]) in infertility due to oligozoospermia===
-In a study, cow’s ghee was administered after therapeutic purgation ([[virechana]]) in 32 infertile patients with oligozoospermia. It showed 80% increase in total sperm count, 41% increase in sperm motility, 12.58% increase in the normal form of sperm, and 45.22% increase in semen volume. It also showed 41.69% decrease in abnormal forms of sperms. An increase in FSH, LH and testosterone levels is reported after the treatment. Improvement in generalized debility, sexual weakness, sexual desire, erectile dysfunction, frequency, and duration of coitus was observed. Ghee possesses anti-oxidant properties as it contains abundant amounts of Vit A and E.<ref name=varsakiya>Varsakiya JN, Goyal M, Thakar A, Donga S, Kathad D. Efficacy of Virechana (therapeutic purgation) followed by Go-Ghrita (cow ghee) in the management of Ksheena Shukra (oligozoospermia): A clinical study. AYU 2019;40:27-33.</ref>
-===Effect of asafoetida===
-Asafoetida in low dose improves the viability, motility, count and morphology of sperms. In higher doses it may have adverse action. In a study, rats treated with asafoetida showed significant increase in epididymal sperm count. Improvement in sperm morphology and viability was reported. Mobility of sperms was found to decrease after treating with asafoetida. Histological study shows an increase in germ cells and signs of spermatogenesis.<ref name=bagheri>Bagheri SM, Yadegari M, Porentezari M, Mirjalili A, Hasanpor A, Dashti RM, et al. Effect of Ferula assa-foetidaoleo gum resin on spermatic parameters and testicular histopathology in male wistar rats. J Ayurveda Integr Med 2015;6:175-80.</ref> It may have a stimulant action on spermatogenesis.
-===Syzygium aromaticum===
-Lower doses of Syzygium aromaticum have a stimulant effect on spermatogenesis. Its higher dose has an adverse action on male reproductive parameters like count, motility, and morphology of sperms.<ref name=mishrark>Mishra RK, Singh SK. Reproductive effects of lipid soluble components of Syzygium aromaticum flower bud in male mice. J Ayurveda Integr Med 2013;4:94-8.</ref>
-===Puga khanda===
-Puga Khanda, an Ayurvedic formulation, improves the seminal volume, total sperm count, and motility. It also showed improvement in sexual desire, penile erection and penile rigidity. The ingredients like Areca catechu, Asparagus racemosus, Pueraria tuberosa, Tribulus terrestris, cow’s milk, ghee have aphrodisiac and antioxidant properties.<ref name=baragi>Baragi PC, Bhat S, Prajapati PK, Baragi UC. Clinical evaluation of V.r.sya effect of Pūga Kha.n.da on sexual health and seminal parameters. Ancient Sci Life 2013;32:134-8.</ref>
-===Ficus religiosa===
-In a study on 20 patients with oligozoospermia, sperm count and semen volume are significantly increased by administering Ficus religiosa (ashwatha) fruit powder after therapeutic purgation ([[virechana]]).<ref>Varsakiya JN, Goyal M, Thakar A, Patel B. Role of Virechana and Ashwatha Phala Churna in the management of Ksheena Shukra (oligozoospermia): A pilot study. Ayu. 2016 Apr-Jun;37(2):113-119. doi: 10.4103/ayu.AYU_71_15. PMID: 29200749; PMCID: PMC5688833.</ref>
-==List of theses done==
-#Rajareddy G (1999): A comparative pharmacotherapeutic study of erandamula and kapikacchu bija with special reference to vrsya karma.  Department of Dravyaguna Vigyan. IPGT&RA Jamnagar
-#Santosh Bhatted (2002): A comparative study of role of vajeekarana drugs administered orally and by basti in the management of klaibhya with reference to erectile dysfunction. Department of Kayachikitsa. IPGT&RA Jamnagar
-#Prakash Mangalasseri (2002): A clinical study of shukragatavata w.s.r to premature ejaculation & its management with Akarakarbhati yoga yapanabasti. Department of Kayachikitsa, IPGT&RA  Jamnagar
-#Sanjay Gupta (2006): A clinical effect of Baladiyapanabasti and vajikarana yoga in the management of sukradushti w.s.r to oligoasthenozoospermia. Department of Kayachikitsa, IPGT&RA  Jamnagar
-#Basil Cardozo (2006): A clinical study on physo-somatic management of sukraavritavata (premature ejaculation) with rasayana yoga and shirodhara. Department of Kayachikitsa, IPGT&RA  Jamnagar
-#Jithesh C Padariya (2010): Effect of pushpadhanva rasa and swayamguptaikshurakbheejachoorna on kshinashukra (oligozoospermia). Department of Kayachikitsa, IPGT&RA  Jamnagar
-#Nakul A Jethva (2011): A Clinical Study on the Effect of Virechana Karma and Amalaki Rasayana in the Management of Kshinashukra w.s.r. to Oligozoospermia. Department of Panchakarma, IPGT&RA  Jamnagar
-#BGSM Sumanasinghe (2016): Experimental evaluation of vrishyakarma (Aphrodisiac activity) of leaf of Clitoria Ternatea Linn. (Aparajita). Department of Dravyaguna Vigyan. IPGT&RA Jamnagar
-#Jitendra Varsakiya (2015): A comparative study of Ashwatthaphalachurna and shvetapalanduswarasabhavitayavani in the management of ksheenashukra W.S.R to oligozoospermia. Department of Kayachikitsa, IPGT&RA  Jamnagar
-#Vasava Ankitkumar Amarsinh (2017): A comparative clinical study of churnaratnam and svaguptadichurna in the management of ksheenashukra W.S.R to oligozoospermia. Department of Kayachikitsa, IPGT&RA  Jamnagar
-#Nikunj M (2012): A comparative study of vrishyabasti and kulinga (Blepharis edulis) after virechana karma in the management of kshinashukra w.s.r to oligozoospermia. Department of Panchakarma, IPGT&RA  Jamnagar
-#Jadav Hasmukh Bhavanbhai (2014): Management of premature ejaculation (shukragatavata) with erandamoolbasti and vanarikalpa- A clinical study. Department of Panchakarma, IPGT&RA  Jamnagar
-==More information==
-[[Vajikarana Adhyaya]], [[Rasayana Adhyaya]]
-==Abbreviations==
-Cha. = Charak, Su. = Sushruta, A. = Ashtanga, S. = Sangraha, Sha. = Shargadara, Sa. = Samhita.
-==List of References==
-The list of references for Vajikarana in Charak Samhita can be seen[[Media:Reference_of_word_Vajikarana_in_Charaka.pdf| here]]
-==References==
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