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Moringa oleifera LAM.
{{#seo:
|title=Charak Samhita
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|keywords= *Shigru, Moringa oleifera LAM., Horse radish tree* Therapeutic use, herbs, researches on dravya, Charak Samhita, Dravyaguna, carakasamhitaonline, carakasamhita, caraka samhita, Ayurveda, Charak Samhita English translation, ancient Ayurveda text, Indian system of medicine, Ayurveda, Charak, Charaka Samhita, agnivesha, atreya, gopal basisht, yogesh deole, charak samhita wikipedia edition, charak samhita new edition, charaka samhita new edition, carak samhita new edition, caraka samhita new edition, research on charak samhita, text book charak samhita, fundamental principles of ayurveda, basic concepts of ayurveda,
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|image_alt=charak samhita
|type=article
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{{Infobox
{{Infobox
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|data4 = Available
|data4 = Available
|label5 = Contributors
|label5 = Contributors
|data5 = --
|data5 = [[Team Dravyaguna]]
|label6 = Year of publication  
|label6 = Year of publication  
|data6 = 2024
|data6 = 2026
|label7 = Publisher  
|label7 = Publisher  
|data7 = [[Charak Samhita Research, Training and Skill Development Centre]]
|data7 = [[Charak Samhita Research, Training and Skill Development Centre]]
|label8 = DOI  
|label8 = DOI  
|data8 = Awaited
|data8 = Awaited
}}
}}


==English name ==
'''[https://en.wikipedia.org/wiki/Moringa_oleifera Moringa oleifera LAM.]''', popularly known as '''Shigru''' (Drumstick plant), is a fast-growing, deciduous tree native to the Indian subcontinent and cultivated across tropical and subtropical regions worldwide. It is widely revered in [[Ayurveda]] as a powerful anti-inflammatory, antimicrobial, and scraping (''lekhan'') drug of choice for managing painful edematous swellings, metabolic disorders, and microbial infections.


== English name ==
Horse radish tree, Drumstick plant
Horse radish tree, Drumstick plant


==Therapeutic Uses1<ref>Anonymous. The Ayurvedic Pharmacopoeia of India. Department of Ayush, Ministry of Health and Family welfare, Govt. of India, New Delhi, Part I. 1986; Volume II:69.</ref>==
== Therapeutic Uses ==
Swelling (sopha), Gulma, Worms (krimiroga), Medoroga, Diseases of spleen (pliharoga), Abscess (vidradhi), Goitre (galaganda).
Swelling (sopha), Gulma, Worms (krimiroga), Medoroga, Diseases of spleen (pliharoga), Abscess (vidradhi), Goitre (galaganda).<ref name="API1986">Anonymous. The Ayurvedic Pharmacopoeia of India. Department of Ayush, Ministry of Health and Family welfare, Govt. of India, New Delhi, Part I. 1986; Volume II:69.</ref>


==Other Varieties/ Other botanical names==
== Other Varieties / Other Botanical names ==
* Guilandina moringa L.
* Guilandina moringa L.
* Hyperanthera moringa (L.) Vahl
* Hyperanthera moringa (L.) Vahl
* Moringa pterygosperma Gaertn. nom. illeg.
* Moringa pterygosperma Gaertn. nom. illeg.


==Bhavaprakasha Nighantu2<ref>Prof. K.C.Chunekar, Bhavprakasha Nighantu, Reprint.2015, Chaukhambha vishvabharti, Guduchyadi Varga, p.324.</ref>==
== Botanical Profile & Traditional Context ==
In traditional medicine, Shigru is classified as a potent Vata and Kapha pacifying agent with sharp (''tikshna'') and hot (''ushna'') properties. It is exceptionally valued for clearing deep-seated tissue toxins, reducing chronic inflammation, and rectifying lipid metabolism (''medoroga'').
 
== Bhavaprakasha Nighantu ==
Mentioned 3 types<ref name="Chunekar2015">Prof. K.C. Chunekar, Bhavprakasha Nighantu, Reprint 2015, Chaukhambha Vishvabharti, Guduchyadi Varga, p. 324.</ref>
# Shweta Shigru
# Shweta Shigru
# Shyama Shigru
# Shyama Shigru
# Rakta Shigru
# Rakta Shigru


==Raja Nighantu3<ref>Dr. Indradev Tripathi, Raj Nighantu of Pandit Narahari, ed.2006, Chaukhambha Krishnadas academy, Varanasi; Mulakadi Varga, Verse no. 26-33, p.193-194.</ref>==
== Raja Nighantu ==
# Shigru
Mentioned 4 types<ref name="Tripathi2006">Dr. Indradev Tripathi, Raj Nighantu of Pandit Narahari, ed. 2006, Chaukhambha Krishnadas Academy, Varanasi; Mulakadi Varga, Verse no. 26-33, p. 193-194.</ref>
# Nila Shigru
# Shigru
# Shweta Shigru
# Nila Shigru
# Rakta Shigru
# Shweta Shigru
   
# Rakta Shigru
 
== Synonyms in Charak Samhita==
 
Shigru, Shobhanjana, Krishnagandha, Mochaka, Tikshnagandha, Madhushigru,


==Synonyms in Bhavaprakasha Nighantu<ref></ref>==
== Synonyms in Charak Samhita ==
Shobhanjana, Shigru, Tikshnagandhaka, Akshiva, Maricha
Shigru, Shobhanjana, Krishnagandha, Mochaka, Tikshnagandha, Madhushigru.


== Ayurvedic pharmacological properties ==  
== Additional Synonyms in Bhavprakasha Nighantu ==
Shobhanjana, Tikshnagandhaka, Akshiva, Maricha.<ref name="ChunekarNighantu">Prof. K.C. Chunekar, Bhavprakasha Nighantu, Reprint 2015, Chaukhambha Vishvabharti, Guduchyadi Varga, p. 324.</ref>


== Ayurvedic Pharmacological Properties ==
{| class="wikitable"
{| class="wikitable"
|+ Properties  
|+ Properties
|-
|-
! Sr.no. !! Pharmacological criteria !! Properties
! Sr.no. !! Pharmacological criteria !! Properties
|-
|-
| 1 || Taste ([[rasa]]) || Pungent (katu), Bitter (tikta)
| 1 || Taste ([[rasa]]) || Pungent (katu), Bitter (tikta)
|-
|-
| 2 || Potency ([[veerya]]) || Hot (ushna)
| 2 || Potency ([[veerya]]) || Hot (ushna)
Line 65: Line 76:
| 3 || Post digestion effect ([[vipaka]]) || Pungent (katu)
| 3 || Post digestion effect ([[vipaka]]) || Pungent (katu)
|-
|-
| 4 || Qualities ([[guna]])|| Light (laghu), Rough (ruksha), Sharp (tikshna)  
| 4 || Qualities ([[guna]]) || Light (laghu), Rough (ruksha), Sharp (tikshna)
|-
|-
| 5 || Actions ([[karma]]) || Pacify [[kapha]] and [[vata]]
| 5 || Actions ([[karma]]) || Pacify [[kapha]] and [[vata]]
|-
|}
|}


== Reference in Charak Samhita and its actions ==  
== Reference in Charak Samhita and its actions ==
 
{| class="wikitable"
{| class="wikitable"
|+ Herbs and their activities
|+ Herbs and their activities
|-
|-
! Sr.no. !! Reference in Charak Samhita !! Activity  
! Sr.no. !! Reference in Charak Samhita !! Activity
|-
| 1 ||Cha.Sa.[[Sutra Sthana]] 1/116 || Shodhana (Twak) vriksha (Parisarpa, Sotha, Arsha, Dadru, Vidradhi, Galaganda, Kustha, Alaji)
|-
| 2 ||Cha.Sa.[[Sutra Sthana]] 2/3 || Shirovirechana (Errhine therapy)
|-
|-
| 3 ||Cha.Sa.[[Sutra Sthana]] 2/23 || Krimighniyavagu
| 1 || Cha.Sa. [[Sutra Sthana]] 1/116 || Shodhana (Twak) vriksha (Parisarpa, Sotha, Arsha, Dadru, Vidradhi, Galaganda, Kustha, Alaji)
|-
|-
| 4 ||Cha.Sa.[[Sutra Sthana]] 3/4 || Churnapradeha
| 2 || Cha.Sa. [[Sutra Sthana]] 2/3 || Shirovirechana (Errhine therapy)
|-
|-
| 5 ||Cha.Sa.[[Sutra Sthana]] 4/9(22) || Svedopagmahakashay
| 3 || Cha.Sa. [[Sutra Sthana]] 2/23 || Krimighniyavagu (gruel for worm infestation)
|-
|-
| 6 ||Cha.Sa.[[Sutra Sthana]] 4/9(27) || Shirovirechanopagmahakashay
| 4 || Cha.Sa. [[Sutra Sthana]] 3/4 || Churnapradeha (external application)
|-
|-
|7
| 5 || Cha.Sa. [[Sutra Sthana]] 4/9(22) || Svedopagmahakashaya (helping diaphoresis/sudation)
|Cha.Sa.[[Sutra Sthana]] 13/10
|Sthavara  Sneha Yoni (Vegetable origin of lipids)
|-
|-
|8
| 6 || Cha.Sa. [[Sutra Sthana]] 4/9(27) || Shirovirechanopagmahakashaya (helping nasal errhine therapy)
|Cha.Sa.[[Sutra Sthana]] 14/31
|Dravya for  Nadi Sweda
|-
|-
|9
| 7 || Cha.Sa. [[Sutra Sthana]] 13/10 || Sthavara Sneha Yoni (Vegetable origin of lipids)
|Cha.Sa.[[Sutra Sthana]] 14/32
|Dravya for  Nadi Sweda
|-
|-
|10
| 8 || Cha.Sa. [[Sutra Sthana]] 14/31 || Dravya for Nadi Sweda (fomentation)
|Cha.Sa.[[Sutra Sthana]] 23/19
|Santarpanajanya  vikar chikitsa
|-
|-
|11
| 9 || Cha.Sa. [[Sutra Sthana]] 14/32 || Dravya for Nadi Sweda (fomentation)
|Cha.Sa.[[Sutra Sthana]] 27/170
|Harita Varga
|-
|-
|12
| 10 || Cha.Sa. [[Sutra Sthana]] 23/19 || Santarpanajanya vikar chikitsa (management of disease due to over nutrition)
|Cha.Sa.[[Sutra Sthana]] 26/84
|Viruddha ahar
|-
|-
|13
| 11 || Cha.Sa. [[Sutra Sthana]] 27/170 || Harita Varga
|Cha.Sa.[[Nidana Sthana]] 2/4
|Nidana
|-
|-
|14
| 12 || Cha.Sa. [[Sutra Sthana]] 26/84 || Viruddha ahara (unwholesome diet)
|Cha.Sa.[[Vimana Sthana]] 6/17
|Abhyantar Krimi  Chikitsa
|-
|-
|15
| 13 || Cha.Sa. [[Nidana Sthana]] 2/4 || Nidana of raktapitta (cause for bleeding disorder)
|Cha.Sa.[[Vimana Sthana]] 6/17
|Abhyantar Krimi  Chikitsa
|-
|-
|16
| 14 || Cha.Sa. [[Vimana Sthana]] 6/17 || Abhyantar Krimi Chikitsa (treatment of worms)
|Cha.Sa.[[Vimana Sthana]] 8/135
|Vaman dravyani
|-
|-
|17
| 15 || Cha.Sa. [[Vimana Sthana]] 8/135 || Vamana dravyani
|Cha.Sa.[[Vimana Sthana]] 8/142
|Katuskandha
|-
|-
|18
| 16 || Cha.Sa. [[Vimana Sthana]] 8/142 || Katuskandha (group of pungent drugs)
|Cha.Sa.[[Vimana Sthana]] 8/142
|Katuskandha
|-
|-
|19
| 17 || Cha.Sa. [[Chikitsa Sthana]] 7/106 || Ingredient in Sweta-karavirapallavadhya Taila
|Cha.Sa.[[Chikitsa Sthana]] 7/106
|Ingredient in Sweta-karavirapallavadhya Tail
|-
|-
|20
| 18 || Cha.Sa. [[Chikitsa Sthana]] 7/109 || Ingredient in Tiktekshvadi Taila for Abhyanga in Vata-Kaphaj Kushtha
|Cha.Sa.[[Chikitsa Sthana]] 7/109
|Ingredient in Tiktekshvadi Taila for Abhyang in Vata-Kaphaj Kushth
|-
|-
|21
| 19 || Cha.Sa. [[Chikitsa Sthana]] 7/113 || Ingredient in Kanakakshiri Taila
|Cha.Sa.[[Chikitsa Sthana]] 7/113
|Ingredient in Kanakakshiri Tail
|-
|-
|22
| 20 || Cha.Sa. [[Chikitsa Sthana]] 7/124 || Bahyaprayogarth Lepa in Vata-Kaphaj Kushtha
|Cha.Sa.[[Chikitsa Sthana]] 7/124
|Bahyaprayogarth Lepa in Vata-Kaphaj Kushth
|-
|-
|23
| 21 || Cha.Sa. [[Chikitsa Sthana]] 8/79 || Ingredient in Shira-Pashva-Ansha Shula nashak lepa
|Cha.Sa.[[Chikitsa Sthana]] 8/79
|Ingredient in Shira-Pashva –Ansha Shula nashak lepa
|-
|-
|24
| 22 || Cha.Sa. [[Chikitsa Sthana]] 8/129 || Ingredient in Atisara nashak Khad-yush
|Cha.Sa.[[Chikitsa Sthana]] 8/129
|Ingredient in Atisar nashak Khad-yush
|-
|-
|25
| 23 || Cha.Sa. [[Chikitsa Sthana]] 10/33 || Ingredient in oil preparation Bahyaprayogartha
|Cha.Sa.[[Chikitsa Sthana]] 10/33
|Ingredient in oil preparation Bahyaprayogartha
|-
|-
|26
| 24 || Cha.Sa. [[Chikitsa Sthana]] 12/67 || As a Snana dravya for Bahyaprayogartha
|Cha.Sa.[[Chikitsa Sthana]] 12/67
|As a Snan dravya for Bahyaprayogarth
|-
|-
|27
| 25 || Cha.Sa. [[Chikitsa Sthana]] 12/70 || Bahyaprayogarth Lepa in Kaphaja Shvayathu
|Cha.Sa.[[Chikitsa Sthana]] 12/70
|Bahyaprayogarth Lepa in Kaphaja Shvayathu
|-
|-
|28
| 26 || Cha.Sa. [[Chikitsa Sthana]] 12/72 || As an Unmardan dravya in Kaphaj Shvayathu
|Cha.Sa.[[Chikitsa Sthana]] 12/72
|As an Unmardan dravya in Kaphaj Shvayathu
|-
|-
|29
| 27 || Cha.Sa. [[Chikitsa Sthana]] 14/45 || Used in swedana kriya (fomentation)
|Cha.Sa.[[Chikitsa Sthana]] 14/45
|Used in swedana kriya
|-
|-
|30
| 28 || Cha.Sa. [[Chikitsa Sthana]] 17/98 || Used in yusha preparation for hikka svasa
|Cha.Sa.[[Chikitsa Sthana]] 17/98
|Used in yusha preparation for hikka svasa
|-
|-
|31
| 29 || Cha.Sa. [[Chikitsa Sthana]] 23/183 || Used in netragata visha, as an anjana prayoga
|Cha.Sa.[[Chikitsa Sthana]] 23/183
|Used in netragata visha, as a anjana prayoga.
|-
|-
|32
| 30 || Cha.Sa. [[Chikitsa Sthana]] 26/66 || Used in Ashmari
|Cha.Sa.[[Chikitsa Sthana]] 26/66
|Used in Ashmari.
|-
|-
|33
| 31 || Cha.Sa. [[Chikitsa Sthana]] 26/67 || Used in Ashmari
|Cha.Sa.[[Chikitsa Sthana]] 26/67
|Used in Ashmari.
|-
|-
|34
| 32 || Cha.Sa. [[Chikitsa Sthana]] 26/186 || Used in Kaphaja Siroroga for Avapeeda nasya
|Cha.Sa.[[Chikitsa Sthana]] 26/186
|Used in Kaphaja Siroroga for Avapeeda nasya.
|-
|-
|35
| 33 || Cha.Sa. [[Chikitsa Sthana]] 26/226 || As an ingredient of Kshara taila
|Cha.Sa.[[Chikitsa Sthana]] 26/226
|As an ingredient of Kshara taila.
|-
|-
|36
| 34 || Cha.Sa. [[Chikitsa Sthana]] 26/237 || Used for aaschotana in Vataja netraroga
|Cha.Sa.[[Chikitsa Sthana]] 26/237
|Used for aaschotana in Vataja netraroga.
|-
|-
|37
| 35 || Cha.Sa. [[Chikitsa Sthana]] 26/240 || As an ingredient of Bruhatyadi varti
|Cha.Sa.[[Chikitsa Sthana]] 26/240
|As an ingredient of Bruhatyadi varti.
|-
|-
|38
| 36 || Cha.Sa. [[Chikitsa Sthana]] 26/245 || As an ingredient of Amrutadi varti
|Cha.Sa.[[Chikitsa Sthana]] 26/245
|As an ingredient of Amrutadi varti.
|-
|-
|39
| 37 || Cha.Sa. [[Chikitsa Sthana]] 27/52 || As an ingredient of Tarkaryadi Parisechana
|Cha.Sa.[[Chikitsa Sthana]] 27/52
|As an ingredient of  Tarkaryadi Parisechana
|-
|-
|40
| 38 || Cha.Sa. [[Chikitsa Sthana]] 27/54 || As an ingredient of Vatsakadi Pralepa
|Cha.Sa.[[Chikitsa Sthana]] 27/54
|As an ingredient of Vatsakadi Pralepa
|-
|-
|41
| 39 || Cha.Sa. [[Chikitsa Sthana]] 27/56 || As an ingredient of Shyonakdi Parisheka and Pralepa
|Cha.Sa.[[Chikitsa Sthana]] 27/56  
|As an ingredient of Shyonakdi Parisheka and Pralepa
|-
|-
|42
| 40 || Cha.Sa. [[Chikitsa Sthana]] 28/130 || As an ingredient of Triphaladi maha sneha
|Cha.Sa.[[Chikitsa Sthana]] 28/130
|As an ingredient of Triphaladi maha sneha.
|-
|-
|43
| 41 || Cha.Sa. [[Chikitsa Sthana]] 28/168 || As an ingredient of Mulakadhya taila
|Cha.Sa.[[Chikitsa Sthana]] 28/168  
|As an ingredient of Mulakadhya taila.
|-
|-
|44
| 42 || Cha.Sa. [[Chikitsa Sthana]] 28/176 || As an ingredient of Mulaka taila
|Cha.Sa.[[Chikitsa Sthana]] 28/176
|As an ingredient of Mulaka taila.
|}
|}


==Dose<ref>Anonymous. The Ayurvedic Pharmacopoeia of India. Department of Ayush, Ministry of Health and Family welfare, Govt. of India, New Delhi, Part I. 1986; Volume II:69.</ref>==
== Dose ==
* Swarasa – 10 – 20 ml
* Swarasa (Juice): 10–20 ml.<ref name="API1986"/>


==Important formulations<ref>Anonymous. The Ayurvedic Pharmacopoeia of India. Department of Ayush, Ministry of Health and Family welfare, Govt. of India, New Delhi, Part I. 1986; Volume II:69.</ref>==
== Important Formulations ==
As per A.P.I.<ref name="API1986"/>
* Ratnagiri Rasa
* Ratnagiri Rasa
* Vishatinduka Taila
* Vishatinduka Taila
* Ekangavira Rasa
* Ekangavira Rasa


 
== Current Availability ==
== Current availability==  
Available
* In India: Tamil Nadu, Karnataka, Andhra Pradesh, Kerala, Maharashtra, Gujarat, Rajasthan, Uttar Pradesh, Bihar, Punjab, Odisha, West Bengal, Madhya Pradesh, Chhattisgarh.
* Out of India: Sri Lanka, Myanmar, Thailand, Indonesia, Philippines, Africa (Kenya, Nigeria, Ethiopia), South America (Brazil, Peru, Venezuela), Southern parts of United States, Saudi Arabia.
 
== Phytochemical Composition ==
The leaves of ''Moringa oleifera'' are rich in proteins, minerals, vitamins (particularly C and E) and β-carotene, and in bioactive compounds such as flavonoids, phenolic acids, glucosinolates and isothiocyanates, tannins and saponins.<ref name="Leone2015b">{{cite journal |last1=Leone |first1=A. |display-authors=etal |year=2015 |title=Nutritional characterization and phenolic profiling of Moringa oleifera leaves grown in Chad, Sahrawi refugee camps, and Haiti |journal=International Journal of Molecular Sciences |volume=16 |issue=8 |pages=18923–18937}}</ref>
* '''Flavonoids:''' Quercetin and kaempferol glycosides were the main phenolic compounds identified in methanolic leaf extracts.
* '''Phenolic acids:''' Salicylic acid (0.14–0.33 mg/100 g) and ferulic acid (6.61–9.69 mg/100 g) were found in leaves grown in Chad, the Sahrawi refugee camps and Haiti.
* '''Isothiocyanates (seeds):''' 4(α-L-rhamnosyloxy)benzyl isothiocyanate, an antimicrobial principle, makes up about 8–10% of defatted, shell-free seeds (see Antimicrobial Activity below).
 
== Pharmacological Activities & Therapeutic Efficacy ==
=== Anti-inflammatory and Anti-arthritic Activity (Sopha) ===
* '''Scientific Evidence:''' In rats with complete Freund's adjuvant-induced arthritis, an ethanol extract of ''Moringa oleifera'' leaves (250 and 500 mg/kg) was reported to prevent the development of arthritis or ameliorate its severity, and also showed dose-dependent anti-nociceptive activity in normal and arthritic rats.<ref name="Mahdi2018">{{cite journal |last1=Mahdi |first1=H. J. |display-authors=etal |year=2018 |title=In vivo anti-arthritic and anti-nociceptive effects of ethanol extract of Moringa oleifera leaves on complete Freund's adjuvant (CFA)-induced arthritis in rats |journal=Integrative Medicine Research |volume=7 |issue=1 |pages=85–94 |doi=10.1016/j.imr.2017.11.002}}</ref>
 
=== Antimicrobial Activity ===
* '''Scientific Evidence:''' 4(α-L-rhamnosyloxy)benzyl isothiocyanate was identified as an active antimicrobial agent from the seeds of ''Moringa oleifera'' and ''M. stenopetala''. It acts on several bacteria and fungi; the minimal bactericidal concentration in vitro was 40 µmol/l for ''Mycobacterium phlei'' and 56 µmol/l for ''Bacillus subtilis''. Roots of ''M. oleifera'' contain this compound and benzyl isothiocyanate but not pterygospermin, as had previously been suggested.<ref name="Eilert1981">{{cite journal |last1=Eilert |first1=U. |last2=Wolters |first2=B. |last3=Nahrstedt |first3=A. |year=1981 |title=The antibiotic principle of seeds of Moringa oleifera and Moringa stenopetala |journal=Planta Medica |volume=42 |issue=5 |pages=55–61 |doi=10.1055/s-2007-971546}}</ref>
 
=== Metabolic Disorders (Medoroga) ===
* '''Scientific Evidence:''' A review of studies on moringa leaf preparations given orally in chronic hyperglycaemia and dyslipidaemia reported beneficial changes in specific biochemical parameters of these conditions.<ref name="Mbikay2012">{{cite journal |last1=Mbikay |first1=M. |year=2012 |title=Therapeutic potential of Moringa oleifera leaves in chronic hyperglycemia and dyslipidemia: a review |journal=Frontiers in Pharmacology |volume=3 |pages=24 |doi=10.3389/fphar.2012.00024}}</ref>
 
== Safety and Limitations of Evidence ==
* '''Clinical evidence:''' A review of the pharmacology of moringa leaves concluded that there are still too few studies in humans to recommend the leaves as medication for the prevention or treatment of diseases; the pharmacological findings cited above come from animal and in vitro studies.<ref name="Leone2015a">{{cite journal |last1=Leone |first1=A. |last2=Spada |first2=A. |last3=Battezzati |first3=A. |last4=Schiraldi |first4=A. |last5=Aristil |first5=J. |last6=Bertoli |first6=S. |year=2015 |title=Cultivation, genetic, ethnopharmacology, phytochemistry and pharmacology of Moringa oleifera leaves: an overview |journal=International Journal of Molecular Sciences |volume=16 |issue=6 |pages=12791–12835 |doi=10.3390/ijms160612791}}</ref>


Available
== Summary of Therapeutic Profile ==
* In India –
{| class="wikitable sortable" style="text-align: left;"
Tamil nadu, Karnataka, Andhra Pradesh, Kerala, Maharashtra, Gujarat, Rajasthan, Uttar Pradesh, Bihar, Punjab, Odisha, West bengal, Madhya Pradesh, Chhattisgarh
|+ Therapeutic Applications of ''Moringa oleifera''
* Out of India –
! Indication
Sri lanka, Myanmar, Thailand, Indonesia, Phillipines, Africa (Kenya, Nigeria, Ethiopia), South america (Brazil, Peru, Venezuela), Southern parts of united states, Saudi arabia
! Active Biomolecules
! Primary Pharmacological Action
|-
| '''Inflammatory Swelling / Arthritis (Sopha)'''
| Leaf ethanol extract (phenolics, flavonoids)
| Anti-arthritic, anti-nociceptive (rat model)
|-
| '''Microbial Infections'''
| 4(α-L-rhamnosyloxy)benzyl isothiocyanate (seeds)
| Antibacterial, antifungal (in vitro)
|-
| '''Metabolic Disorders (Medoroga)'''
| Leaf preparations
| Beneficial changes in glycaemic and lipid parameters (reviewed studies)
|}


== Current researches ==
== References ==
{{Reflist|refs=
<ref name="API1986">Anonymous. The Ayurvedic Pharmacopoeia of India. Department of Ayush, Ministry of Health and Family welfare, Govt. of India, New Delhi, Part I. 1986; Volume II:69.</ref>
<ref name="Chunekar2015">Prof. K.C. Chunekar, Bhavprakasha Nighantu, Reprint 2015, Chaukhambha Vishvabharti, Guduchyadi Varga, p. 324.</ref>
<ref name="Tripathi2006">Dr. Indradev Tripathi, Raj Nighantu of Pandit Narahari, ed. 2006, Chaukhambha Krishnadas Academy, Varanasi; Mulakadi Varga, Verse no. 26-33, p. 193-194.</ref>
<ref name="ChunekarNighantu">Prof. K.C. Chunekar, Bhavprakasha Nighantu, Reprint 2015, Chaukhambha Vishvabharti, Guduchyadi Varga, p. 324.</ref>
<ref name="Leone2015b">{{cite journal |last1=Leone |first1=A. |display-authors=etal |year=2015 |title=Nutritional characterization and phenolic profiling of Moringa oleifera leaves grown in Chad, Sahrawi refugee camps, and Haiti |journal=International Journal of Molecular Sciences |volume=16 |issue=8 |pages=18923–18937}}</ref>
<ref name="Mahdi2018">{{cite journal |last1=Mahdi |first1=H. J. |display-authors=etal |year=2018 |title=In vivo anti-arthritic and anti-nociceptive effects of ethanol extract of Moringa oleifera leaves on complete Freund's adjuvant (CFA)-induced arthritis in rats |journal=Integrative Medicine Research |volume=7 |issue=1 |pages=85–94 |doi=10.1016/j.imr.2017.11.002}}</ref>
<ref name="Eilert1981">{{cite journal |last1=Eilert |first1=U. |last2=Wolters |first2=B. |last3=Nahrstedt |first3=A. |year=1981 |title=The antibiotic principle of seeds of Moringa oleifera and Moringa stenopetala |journal=Planta Medica |volume=42 |issue=5 |pages=55–61 |doi=10.1055/s-2007-971546}}</ref>
<ref name="Mbikay2012">{{cite journal |last1=Mbikay |first1=M. |year=2012 |title=Therapeutic potential of Moringa oleifera leaves in chronic hyperglycemia and dyslipidemia: a review |journal=Frontiers in Pharmacology |volume=3 |pages=24 |doi=10.3389/fphar.2012.00024}}</ref>
<ref name="Leone2015a">{{cite journal |last1=Leone |first1=A. |last2=Spada |first2=A. |last3=Battezzati |first3=A. |last4=Schiraldi |first4=A. |last5=Aristil |first5=J. |last6=Bertoli |first6=S. |year=2015 |title=Cultivation, genetic, ethnopharmacology, phytochemistry and pharmacology of Moringa oleifera leaves: an overview |journal=International Journal of Molecular Sciences |volume=16 |issue=6 |pages=12791–12835 |doi=10.3390/ijms160612791}}</ref>
}}


[[Category: Database of herbs and minerals | Herbs]]
[[Category: Database of herbs and minerals | Herbs]]
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Latest revision as of 12:09, 18 October 2026


Shigru
Section/Chapter Herb database/Shigru
Botanical name(s) Moringa oleifera LAM.
Family Moringaceae
Availability Available
Contributors Team Dravyaguna
Year of publication 2026
Publisher Charak Samhita Research, Training and Skill Development Centre
DOI Awaited

Moringa oleifera LAM., popularly known as Shigru (Drumstick plant), is a fast-growing, deciduous tree native to the Indian subcontinent and cultivated across tropical and subtropical regions worldwide. It is widely revered in Ayurveda as a powerful anti-inflammatory, antimicrobial, and scraping (lekhan) drug of choice for managing painful edematous swellings, metabolic disorders, and microbial infections.

English name

Horse radish tree, Drumstick plant

Therapeutic Uses

Swelling (sopha), Gulma, Worms (krimiroga), Medoroga, Diseases of spleen (pliharoga), Abscess (vidradhi), Goitre (galaganda).[1]

Other Varieties / Other Botanical names

  • Guilandina moringa L.
  • Hyperanthera moringa (L.) Vahl
  • Moringa pterygosperma Gaertn. nom. illeg.

Botanical Profile & Traditional Context

In traditional medicine, Shigru is classified as a potent Vata and Kapha pacifying agent with sharp (tikshna) and hot (ushna) properties. It is exceptionally valued for clearing deep-seated tissue toxins, reducing chronic inflammation, and rectifying lipid metabolism (medoroga).

Bhavaprakasha Nighantu

Mentioned 3 types[2]

  1. Shweta Shigru
  2. Shyama Shigru
  3. Rakta Shigru

Raja Nighantu

Mentioned 4 types[3]

  1. Shigru
  2. Nila Shigru
  3. Shweta Shigru
  4. Rakta Shigru

Synonyms in Charak Samhita

Shigru, Shobhanjana, Krishnagandha, Mochaka, Tikshnagandha, Madhushigru.

Additional Synonyms in Bhavprakasha Nighantu

Shobhanjana, Tikshnagandhaka, Akshiva, Maricha.[4]

Ayurvedic Pharmacological Properties

Properties
Sr.no. Pharmacological criteria Properties
1 Taste (rasa) Pungent (katu), Bitter (tikta)
2 Potency (veerya) Hot (ushna)
3 Post digestion effect (vipaka) Pungent (katu)
4 Qualities (guna) Light (laghu), Rough (ruksha), Sharp (tikshna)
5 Actions (karma) Pacify kapha and vata

Reference in Charak Samhita and its actions

Herbs and their activities
Sr.no. Reference in Charak Samhita Activity
1 Cha.Sa. Sutra Sthana 1/116 Shodhana (Twak) vriksha (Parisarpa, Sotha, Arsha, Dadru, Vidradhi, Galaganda, Kustha, Alaji)
2 Cha.Sa. Sutra Sthana 2/3 Shirovirechana (Errhine therapy)
3 Cha.Sa. Sutra Sthana 2/23 Krimighniyavagu (gruel for worm infestation)
4 Cha.Sa. Sutra Sthana 3/4 Churnapradeha (external application)
5 Cha.Sa. Sutra Sthana 4/9(22) Svedopagmahakashaya (helping diaphoresis/sudation)
6 Cha.Sa. Sutra Sthana 4/9(27) Shirovirechanopagmahakashaya (helping nasal errhine therapy)
7 Cha.Sa. Sutra Sthana 13/10 Sthavara Sneha Yoni (Vegetable origin of lipids)
8 Cha.Sa. Sutra Sthana 14/31 Dravya for Nadi Sweda (fomentation)
9 Cha.Sa. Sutra Sthana 14/32 Dravya for Nadi Sweda (fomentation)
10 Cha.Sa. Sutra Sthana 23/19 Santarpanajanya vikar chikitsa (management of disease due to over nutrition)
11 Cha.Sa. Sutra Sthana 27/170 Harita Varga
12 Cha.Sa. Sutra Sthana 26/84 Viruddha ahara (unwholesome diet)
13 Cha.Sa. Nidana Sthana 2/4 Nidana of raktapitta (cause for bleeding disorder)
14 Cha.Sa. Vimana Sthana 6/17 Abhyantar Krimi Chikitsa (treatment of worms)
15 Cha.Sa. Vimana Sthana 8/135 Vamana dravyani
16 Cha.Sa. Vimana Sthana 8/142 Katuskandha (group of pungent drugs)
17 Cha.Sa. Chikitsa Sthana 7/106 Ingredient in Sweta-karavirapallavadhya Taila
18 Cha.Sa. Chikitsa Sthana 7/109 Ingredient in Tiktekshvadi Taila for Abhyanga in Vata-Kaphaj Kushtha
19 Cha.Sa. Chikitsa Sthana 7/113 Ingredient in Kanakakshiri Taila
20 Cha.Sa. Chikitsa Sthana 7/124 Bahyaprayogarth Lepa in Vata-Kaphaj Kushtha
21 Cha.Sa. Chikitsa Sthana 8/79 Ingredient in Shira-Pashva-Ansha Shula nashak lepa
22 Cha.Sa. Chikitsa Sthana 8/129 Ingredient in Atisara nashak Khad-yush
23 Cha.Sa. Chikitsa Sthana 10/33 Ingredient in oil preparation Bahyaprayogartha
24 Cha.Sa. Chikitsa Sthana 12/67 As a Snana dravya for Bahyaprayogartha
25 Cha.Sa. Chikitsa Sthana 12/70 Bahyaprayogarth Lepa in Kaphaja Shvayathu
26 Cha.Sa. Chikitsa Sthana 12/72 As an Unmardan dravya in Kaphaj Shvayathu
27 Cha.Sa. Chikitsa Sthana 14/45 Used in swedana kriya (fomentation)
28 Cha.Sa. Chikitsa Sthana 17/98 Used in yusha preparation for hikka svasa
29 Cha.Sa. Chikitsa Sthana 23/183 Used in netragata visha, as an anjana prayoga
30 Cha.Sa. Chikitsa Sthana 26/66 Used in Ashmari
31 Cha.Sa. Chikitsa Sthana 26/67 Used in Ashmari
32 Cha.Sa. Chikitsa Sthana 26/186 Used in Kaphaja Siroroga for Avapeeda nasya
33 Cha.Sa. Chikitsa Sthana 26/226 As an ingredient of Kshara taila
34 Cha.Sa. Chikitsa Sthana 26/237 Used for aaschotana in Vataja netraroga
35 Cha.Sa. Chikitsa Sthana 26/240 As an ingredient of Bruhatyadi varti
36 Cha.Sa. Chikitsa Sthana 26/245 As an ingredient of Amrutadi varti
37 Cha.Sa. Chikitsa Sthana 27/52 As an ingredient of Tarkaryadi Parisechana
38 Cha.Sa. Chikitsa Sthana 27/54 As an ingredient of Vatsakadi Pralepa
39 Cha.Sa. Chikitsa Sthana 27/56 As an ingredient of Shyonakdi Parisheka and Pralepa
40 Cha.Sa. Chikitsa Sthana 28/130 As an ingredient of Triphaladi maha sneha
41 Cha.Sa. Chikitsa Sthana 28/168 As an ingredient of Mulakadhya taila
42 Cha.Sa. Chikitsa Sthana 28/176 As an ingredient of Mulaka taila

Dose

  • Swarasa (Juice): 10–20 ml.[1]

Important Formulations

As per A.P.I.[1]

  • Ratnagiri Rasa
  • Vishatinduka Taila
  • Ekangavira Rasa

Current Availability

Available

  • In India: Tamil Nadu, Karnataka, Andhra Pradesh, Kerala, Maharashtra, Gujarat, Rajasthan, Uttar Pradesh, Bihar, Punjab, Odisha, West Bengal, Madhya Pradesh, Chhattisgarh.
  • Out of India: Sri Lanka, Myanmar, Thailand, Indonesia, Philippines, Africa (Kenya, Nigeria, Ethiopia), South America (Brazil, Peru, Venezuela), Southern parts of United States, Saudi Arabia.

Phytochemical Composition

The leaves of Moringa oleifera are rich in proteins, minerals, vitamins (particularly C and E) and β-carotene, and in bioactive compounds such as flavonoids, phenolic acids, glucosinolates and isothiocyanates, tannins and saponins.[5]

  • Flavonoids: Quercetin and kaempferol glycosides were the main phenolic compounds identified in methanolic leaf extracts.
  • Phenolic acids: Salicylic acid (0.14–0.33 mg/100 g) and ferulic acid (6.61–9.69 mg/100 g) were found in leaves grown in Chad, the Sahrawi refugee camps and Haiti.
  • Isothiocyanates (seeds): 4(α-L-rhamnosyloxy)benzyl isothiocyanate, an antimicrobial principle, makes up about 8–10% of defatted, shell-free seeds (see Antimicrobial Activity below).

Pharmacological Activities & Therapeutic Efficacy

Anti-inflammatory and Anti-arthritic Activity (Sopha)

  • Scientific Evidence: In rats with complete Freund's adjuvant-induced arthritis, an ethanol extract of Moringa oleifera leaves (250 and 500 mg/kg) was reported to prevent the development of arthritis or ameliorate its severity, and also showed dose-dependent anti-nociceptive activity in normal and arthritic rats.[6]

Antimicrobial Activity

  • Scientific Evidence: 4(α-L-rhamnosyloxy)benzyl isothiocyanate was identified as an active antimicrobial agent from the seeds of Moringa oleifera and M. stenopetala. It acts on several bacteria and fungi; the minimal bactericidal concentration in vitro was 40 µmol/l for Mycobacterium phlei and 56 µmol/l for Bacillus subtilis. Roots of M. oleifera contain this compound and benzyl isothiocyanate but not pterygospermin, as had previously been suggested.[7]

Metabolic Disorders (Medoroga)

  • Scientific Evidence: A review of studies on moringa leaf preparations given orally in chronic hyperglycaemia and dyslipidaemia reported beneficial changes in specific biochemical parameters of these conditions.[8]

Safety and Limitations of Evidence

  • Clinical evidence: A review of the pharmacology of moringa leaves concluded that there are still too few studies in humans to recommend the leaves as medication for the prevention or treatment of diseases; the pharmacological findings cited above come from animal and in vitro studies.[9]

Summary of Therapeutic Profile

Therapeutic Applications of Moringa oleifera
Indication Active Biomolecules Primary Pharmacological Action
Inflammatory Swelling / Arthritis (Sopha) Leaf ethanol extract (phenolics, flavonoids) Anti-arthritic, anti-nociceptive (rat model)
Microbial Infections 4(α-L-rhamnosyloxy)benzyl isothiocyanate (seeds) Antibacterial, antifungal (in vitro)
Metabolic Disorders (Medoroga) Leaf preparations Beneficial changes in glycaemic and lipid parameters (reviewed studies)

References

  1. ↑ 1.0 1.1 1.2 Anonymous. The Ayurvedic Pharmacopoeia of India. Department of Ayush, Ministry of Health and Family welfare, Govt. of India, New Delhi, Part I. 1986; Volume II:69.
  2. ↑ Prof. K.C. Chunekar, Bhavprakasha Nighantu, Reprint 2015, Chaukhambha Vishvabharti, Guduchyadi Varga, p. 324.
  3. ↑ Dr. Indradev Tripathi, Raj Nighantu of Pandit Narahari, ed. 2006, Chaukhambha Krishnadas Academy, Varanasi; Mulakadi Varga, Verse no. 26-33, p. 193-194.
  4. ↑ Prof. K.C. Chunekar, Bhavprakasha Nighantu, Reprint 2015, Chaukhambha Vishvabharti, Guduchyadi Varga, p. 324.
  5. ↑ Leone, A.; et al. (2015). "Nutritional characterization and phenolic profiling of Moringa oleifera leaves grown in Chad, Sahrawi refugee camps, and Haiti". International Journal of Molecular Sciences. 16 (8): 18923–18937. 
  6. ↑ Mahdi, H. J.; et al. (2018). "In vivo anti-arthritic and anti-nociceptive effects of ethanol extract of Moringa oleifera leaves on complete Freund's adjuvant (CFA)-induced arthritis in rats". Integrative Medicine Research. 7 (1): 85–94. doi:10.1016/j.imr.2017.11.002. 
  7. ↑ Eilert, U.; Wolters, B.; Nahrstedt, A. (1981). "The antibiotic principle of seeds of Moringa oleifera and Moringa stenopetala". Planta Medica. 42 (5): 55–61. doi:10.1055/s-2007-971546. 
  8. ↑ Mbikay, M. (2012). "Therapeutic potential of Moringa oleifera leaves in chronic hyperglycemia and dyslipidemia: a review". Frontiers in Pharmacology. 3: 24. doi:10.3389/fphar.2012.00024. 
  9. ↑ Leone, A.; Spada, A.; Battezzati, A.; Schiraldi, A.; Aristil, J.; Bertoli, S. (2015). "Cultivation, genetic, ethnopharmacology, phytochemistry and pharmacology of Moringa oleifera leaves: an overview". International Journal of Molecular Sciences. 16 (6): 12791–12835. doi:10.3390/ijms160612791. 
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