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This agni is responsible for all amylolytic, proteolytic and lipolytic enzymes secreted by various exocrine glands in the gut, which actually cause digestion, i.e., breaking down different macromolecules into their constituent units.<ref>Patwardhan K/ Vidhi Vimarsha of Grahani Chikitsa. In Charak Samhita New Edition. Available from https://www.carakasamhitaonline.com/index.php?title=Grahani_Chikitsa#Areas_of_Further_Research</ref>   

This agni is responsible for all amylolytic, proteolytic and lipolytic enzymes secreted by various exocrine glands in the gut, which actually cause digestion, i.e., breaking down different macromolecules into their constituent units.<ref>Patwardhan K/ Vidhi Vimarsha of Grahani Chikitsa. In Charak Samhita New Edition. Available from https://www.carakasamhitaonline.com/index.php?title=Grahani_Chikitsa#Areas_of_Further_Research</ref>   

2. Bhutagni has five fundamental elements, corresponding to respective mahabhuta. Those are: parthiva ([[pruthvi mahabhuta]] dominant), apya ([[apa mahabhuta]] dominant), tejasa (teja or [[agni mahabhuta]] dominant), vayavya ( [[vayu mahabhuta]] dominant) and nabhasa ( [[akasha mahabhuta]] dominant). They act on the corresponding substrate based on [[mahabhuta]] composition to make them homologous to body constituents. This includes factors responsible for digestion and metabolism at the organic level. Five types of bhutagni act after jatharagni, but before dhatvagni on the food and its metabolites. This represents the basic metabolism of various food components and minerals at hepatic level like carbohydrate, protein and fat metabolism.  

2. Bhutagni has five fundamental elements, corresponding to respective mahabhuta. Those are: parthiva ([[prithvi mahabhuta]] dominant), apya ([[jala mahabhuta]] dominant), tejasa (teja or [[agni mahabhuta]] dominant), vayavya ( [[vayu mahabhuta]] dominant) and nabhasa ( [[akasha mahabhuta]] dominant). They act on the corresponding substrate based on [[mahabhuta]] composition to make them homologous to body constituents. This includes factors responsible for digestion and metabolism at the organic level. Five types of bhutagni act after jatharagni, but before dhatvagni on the food and its metabolites. This represents the basic metabolism of various food components and minerals at hepatic level like carbohydrate, protein and fat metabolism.  

This agni carries out the absorption of nutrients in the liver, which plays an essential role in metabolism. Several processes such as trans-amination, de-amination, beta-oxidation of fatty acids, glycolysis etc. take place in the liver. Therefore, the overall intermediary metabolism (involving fats, carbohydrates and proteins) can be understood as the functioning of the bhutagni.  

This agni carries out the absorption of nutrients in the liver, which plays an essential role in metabolism. Several processes such as trans-amination, de-amination, beta-oxidation of fatty acids, glycolysis etc. take place in the liver. Therefore, the overall intermediary metabolism (involving fats, carbohydrates and proteins) can be understood as the functioning of the bhutagni.  

All hormones (such as insulin, growth hormone, thyroid hormones, testosterone etc.) that promote the transportation of various nutrients into the cells, along with the enzymes participating in the Kreb’s cycle, are to be included under the term dhatvagni. 4

All hormones (such as insulin, growth hormone, thyroid hormones, testosterone etc.) that promote the transportation of various nutrients into the cells, along with the enzymes participating in the Kreb’s cycle, are to be included under the term dhatvagni. 4

All three classes with thirteen agni are interconnected and interdependent. The energy mechanism takes place in every body cell. This shows agni is present in every cell. Mitochondria are the powerhouse of the cell. The release of adenocine tri phosphate (ATP) to give energy is an example of agni working at cellular level.  

All three classes with thirteen agni are interconnected and interdependent. The energy mechanism takes place in every body cell. This shows agni is present in every cell. Mitochondria are the powerhouse of the cell. The release of adenocine tri phosphate (ATP) to give energy is an example of agni working at cellular level.

===II. Four types of digestive patterns ===

===II. Four types of digestive patterns ===