| Likewise, the enema administered predominantly containing ''sneha'' (oil) is known as ''anuvasana basti''. Among these two types of enema, ''niruha'' (decoction enema) is considered superior to ''anuvasana'' (oil enema) because it is more effective in the elimination of vitiated factors. Details about these drugs have been mentioned in [[Vimana Sthana]] (Cha. Vi. 8/ 138-144). | | Likewise, the enema administered predominantly containing ''sneha'' (oil) is known as ''anuvasana basti''. Among these two types of enema, ''niruha'' (decoction enema) is considered superior to ''anuvasana'' (oil enema) because it is more effective in the elimination of vitiated factors. Details about these drugs have been mentioned in [[Vimana Sthana]] (Cha. Vi. 8/ 138-144). |
− | The pharmacodynamics of systemic effect of ''basti'' (enema) may be understood through the absorption mechanism, concept of systems biology, neural stimulation mechanism, and excretory mechanism. As it is a homogenous emulsion mixture of honey, ''saindhava'' (salt), ''sneha dravya'' (oil/unctuous material), ''kalka'' (paste of drugs), and decoction of crude drugs which is given through rectum. Through rectal route large quantity of drugs can be delivered for systemic circulation. The concept of systems biology is that a change at cellular level can bring changes in tissues, organs and consequently in the whole body. As per recent advancements in medicine, the intestine not only is a highly vascular organ, but is also a highly innervated organ that forms an "enteric nervous system" (ENS). ENS may work synergistically with the central nervous system of body. The cleansing action of ''basti'' (enema) is related to the facilitation of excretion of morbid substances responsible for the disease process into the colon, from where it is evacuated.<ref> www.ijpba.info/ijpba/index.php/ijpba/article/viewFile/758/519 </ref> [ ] | + | The pharmacodynamics of systemic effect of ''basti'' (enema) may be understood through the absorption mechanism, concept of systems biology, neural stimulation mechanism, and excretory mechanism. As it is a homogenous emulsion mixture of honey, ''saindhava'' (salt), ''sneha dravya'' (oil/unctuous material), ''kalka'' (paste of drugs), and decoction of crude drugs which is given through rectum. Through rectal route large quantity of drugs can be delivered for systemic circulation. The concept of systems biology is that a change at cellular level can bring changes in tissues, organs and consequently in the whole body. As per recent advancements in medicine, the intestine not only is a highly vascular organ, but is also a highly innervated organ that forms an "enteric nervous system" (ENS). ENS may work synergistically with the central nervous system of body. The cleansing action of ''basti'' (enema) is related to the facilitation of excretion of morbid substances responsible for the disease process into the colon, from where it is evacuated.<ref> www.ijpba.info/ijpba/index.php/ijpba/article/viewFile/758/519 </ref> [verse 11-14] |