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	<entry>
		<id>https://www.carakasamhitaonline.com/index.php?title=Swabhavoparam_vada&amp;diff=44619&amp;oldid=prev</id>
		<title>Agnivesha at 18:47, 23 February 2024</title>
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		<updated>2024-02-23T18:47:54Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 18:47, 23 February 2024&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l18&quot;&gt;Line 18:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 18:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|data2 = Mali Vaishali P. &amp;lt;sup&amp;gt;1&amp;lt;/sup&amp;gt;, &amp;lt;br/&amp;gt;Nawkar Madhumati S. &amp;lt;sup&amp;gt;2&amp;lt;/sup&amp;gt;   &lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|data2 = Mali Vaishali P. &amp;lt;sup&amp;gt;1&amp;lt;/sup&amp;gt;, &amp;lt;br/&amp;gt;Nawkar Madhumati S. &amp;lt;sup&amp;gt;2&amp;lt;/sup&amp;gt;   &lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|label3 = Reviewers  &lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|label3 = Reviewers  &lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|data3 = Kashikar V.A. &amp;lt;sup&amp;gt;3&amp;lt;/sup&amp;gt;&amp;lt;br/&amp;gt;Basisht G.&amp;lt;sup&amp;gt;4&amp;lt;/sup&amp;gt;,   &lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|data3 = Kashikar V.A. &amp;lt;sup&amp;gt;3&amp;lt;/sup&amp;gt;&amp;lt;br/&amp;gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[Gopal Basisht|&lt;/ins&gt;Basisht G.&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;]]&lt;/ins&gt;&amp;lt;sup&amp;gt;4&amp;lt;/sup&amp;gt;,   &lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|label4 = Editor  &lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|label4 = Editor  &lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|data4 = Deole Y.S.&amp;lt;sup&amp;gt;5&amp;lt;/sup&amp;gt;  &lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|data4 = &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[Yogesh Deole|&lt;/ins&gt;Deole Y.S.&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;]]&lt;/ins&gt;&amp;lt;sup&amp;gt;5&amp;lt;/sup&amp;gt;  &lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|label5 = Affiliations  &lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|label5 = Affiliations  &lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|data5 = &amp;lt;sup&amp;gt;1&amp;lt;/sup&amp;gt; Department of Samhita-Siddhanta, Ch. Brahm Prakash Ayurved Charak Sansthan, New Delhi. India &amp;lt;br/&amp;gt;&amp;lt;sup&amp;gt;2&amp;lt;/sup&amp;gt; Department of Sanskrit Samhita Siddhanta, R. T. Ayurved Mahavidyalaya, Akola, Maharashtra, India &amp;lt;br/&amp;gt;&amp;lt;sup&amp;gt;3&amp;lt;/sup&amp;gt; Department of Sanskrit Samhita Siddhanta, National Institute of Ayurveda, Jaipur, India  &amp;lt;br/&amp;gt;&amp;lt;sup&amp;gt;4&amp;lt;/sup&amp;gt; Rheumatologist, Orlando, Florida, U.S.A. &amp;lt;br/&amp;gt;&amp;lt;sup&amp;gt;5&amp;lt;/sup&amp;gt; Department of Kayachikitsa, G. J. Patel Institute of Ayurvedic Studies and Research, New Vallabh Vidyanagar, Gujarat, India  &lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|data5 = &amp;lt;sup&amp;gt;1&amp;lt;/sup&amp;gt; Department of Samhita-Siddhanta, Ch. Brahm Prakash Ayurved Charak Sansthan, New Delhi. India &amp;lt;br/&amp;gt;&amp;lt;sup&amp;gt;2&amp;lt;/sup&amp;gt; Department of Sanskrit Samhita Siddhanta, R. T. Ayurved Mahavidyalaya, Akola, Maharashtra, India &amp;lt;br/&amp;gt;&amp;lt;sup&amp;gt;3&amp;lt;/sup&amp;gt; Department of Sanskrit Samhita Siddhanta, National Institute of Ayurveda, Jaipur, India  &amp;lt;br/&amp;gt;&amp;lt;sup&amp;gt;4&amp;lt;/sup&amp;gt; Rheumatologist, Orlando, Florida, U.S.A. &amp;lt;br/&amp;gt;&amp;lt;sup&amp;gt;5&amp;lt;/sup&amp;gt; Department of Kayachikitsa, G. J. Patel Institute of Ayurvedic Studies and Research, New Vallabh Vidyanagar, Gujarat, India  &lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Agnivesha</name></author>
	</entry>
	<entry>
		<id>https://www.carakasamhitaonline.com/index.php?title=Swabhavoparam_vada&amp;diff=42310&amp;oldid=prev</id>
		<title>Agnivesha at 11:33, 2 March 2023</title>
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		<updated>2023-03-02T11:33:05Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 11:33, 2 March 2023&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l36&quot;&gt;Line 36:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 36:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;p style=&amp;#039;text-align:justify;&amp;#039;&amp;gt;Swabhava means a state of being, natural state or constitution, innate or inherent disposition, nature, impulse, and spontaneity.&amp;lt;ref name=&amp;quot;ref2&amp;quot;&amp;gt;MONIER-WILLIAMS, M. (1899). A Sanskrit-English dictionary: Etymologically and philologically arranged with special reference to Cognate indo- European languages. Oxford, The Clarendon Press, page-1276. &amp;lt;/ref&amp;gt;&amp;lt;br/&amp;gt; Uparama means to cease from motion, stop, be inactive or quiet, cessation or discontinuance, ending, desisting from, or death. Uparama means vinaasha, destruction or abstinence or avoidance, desisting, discontinuance.&amp;lt;ref name=&amp;quot;ref3&amp;quot;&amp;gt;MONIER-WILLIAMS, M. (1899). A Sanskrit-English dictionary: Etymologically and philologically arranged with special reference to Cognate indo- European languages. Oxford, The Clarendon Press, page-204 &amp;lt;/ref&amp;gt;&amp;lt;br/&amp;gt;Vada means discussion. Thus the word &amp;#039;swabhavoparama vada&amp;#039; means discussion on the theory of innate or natural destruction.&amp;lt;br/&amp;gt;Destruction of any object&amp;#039;s nature, qualities, or form is known as Swabhavoparam vada.&amp;lt;ref name=&amp;quot;ref4&amp;quot;&amp;gt;Jalpakalpataru, Charak. Sutra Sthana, Cha.16 Chikitsaprabhruteeya Adhyaya ver.28. In: Narendranath Sengupta &amp;amp; Balaichandra Sengupta, Editor. Charak Samhita. 2nd part, Reprint. New Delhi: Rashtriya Sanskrit Sansthan; 2002.p.673. &amp;lt;/ref&amp;gt; Swabhavoparam vada forms the basis for managing causative factors (hetuviparita chikitsa).&amp;lt;/p&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;p style=&amp;#039;text-align:justify;&amp;#039;&amp;gt;Swabhava means a state of being, natural state or constitution, innate or inherent disposition, nature, impulse, and spontaneity.&amp;lt;ref name=&amp;quot;ref2&amp;quot;&amp;gt;MONIER-WILLIAMS, M. (1899). A Sanskrit-English dictionary: Etymologically and philologically arranged with special reference to Cognate indo- European languages. Oxford, The Clarendon Press, page-1276. &amp;lt;/ref&amp;gt;&amp;lt;br/&amp;gt; Uparama means to cease from motion, stop, be inactive or quiet, cessation or discontinuance, ending, desisting from, or death. Uparama means vinaasha, destruction or abstinence or avoidance, desisting, discontinuance.&amp;lt;ref name=&amp;quot;ref3&amp;quot;&amp;gt;MONIER-WILLIAMS, M. (1899). A Sanskrit-English dictionary: Etymologically and philologically arranged with special reference to Cognate indo- European languages. Oxford, The Clarendon Press, page-204 &amp;lt;/ref&amp;gt;&amp;lt;br/&amp;gt;Vada means discussion. Thus the word &amp;#039;swabhavoparama vada&amp;#039; means discussion on the theory of innate or natural destruction.&amp;lt;br/&amp;gt;Destruction of any object&amp;#039;s nature, qualities, or form is known as Swabhavoparam vada.&amp;lt;ref name=&amp;quot;ref4&amp;quot;&amp;gt;Jalpakalpataru, Charak. Sutra Sthana, Cha.16 Chikitsaprabhruteeya Adhyaya ver.28. In: Narendranath Sengupta &amp;amp; Balaichandra Sengupta, Editor. Charak Samhita. 2nd part, Reprint. New Delhi: Rashtriya Sanskrit Sansthan; 2002.p.673. &amp;lt;/ref&amp;gt; Swabhavoparam vada forms the basis for managing causative factors (hetuviparita chikitsa).&amp;lt;/p&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;== Elucidating the concept of swabhavoparama vada theorized in [[Charak Samhita New Edition|Charak Samhita]]&amp;lt;ref name=&quot;ref5&quot;&amp;gt;Murthy A.R.V., Magare R.. Chikitsaprabhritiya Adhyaya verse 27-36. In: Mangalasseri P., Deole Y.S., Basisht G., eds. Charak Samhita New Edition. 1st ed. Jamnagar, Ind: CSRTSDC; 2020. https://www.carakasamhitaonline.com/index.php?title=Chikitsaprabhritiya_Adhyaya&amp;amp;oldid=41146. Accessed February 14, 2023.&amp;lt;/ref&amp;gt; ==&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;== Elucidating the concept of swabhavoparama vada theorized in [[Charak Samhita New Edition|Charak Samhita]]&amp;lt;ref name=&quot;ref5&quot;&amp;gt;Murthy A.R.V., Magare R.. Chikitsaprabhritiya Adhyaya verse 27-36. In: Mangalasseri P., Deole Y.S., Basisht G., eds. &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;[[&lt;/ins&gt;Charak Samhita New Edition&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;|Charak Samhita New Edition]]&lt;/ins&gt;. 1st ed. Jamnagar, Ind: CSRTSDC; 2020. https://www.carakasamhitaonline.com/index.php?title=Chikitsaprabhritiya_Adhyaya&amp;amp;oldid=41146. Accessed February 14, 2023.&amp;lt;/ref&amp;gt; ==&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;p style=&amp;#039;text-align:justify;&amp;#039;&amp;gt;Most philosophical schools talk about creation. And further interrogate the cause of the creation, the universe. [[Ayurveda|Ayurveda]] deals with the biological processes, predominantly concerning the human [[Sharira|body]]. This may be why Charak&amp;#039;s treatise discusses the destruction and its place and utility for physicians.  &amp;lt;br/&amp;gt;In the context of the theory of natural destruction, the sequential order of the tetrad suggests the logical progression in the clinical training of [[Ayurveda|Ayurveda]] scholars: from a foundational course in therapeutics to more specialized procedures, including purification therapies.  Kalpana chatushka tetrad describes the planning of purification therapies. It addresses all the aspects regarding the use of medicines for purification purposes. In the last chapter of this tetrad, the signs, and symptoms of excess and less purification are explained, then after swabhavoparam vada is discussed.  &amp;lt;br/&amp;gt;While explaining the importance of purification therapy, it is mentioned that morbid [[Dosha|doshas]] evacuated by purification therapies do not recur. Like plants,  if morbidities are not uprooted completely, the diseases would recur or relapse almost certainly. If the manifestation of the disease is a transient phase and can remit automatically, then what are the objectives and importance of chikitsa? This query has been raised by scholars. In response to this, in the course of explaining the main objectives and applicability of therapy (chikitsa), Acharya Atreya has described the swabhavoparam vada.&amp;lt;ref name=&amp;quot;ref6&amp;quot;&amp;gt;Shivadas Sen, Charak. Sutra Sthana, Cha.16 Chikitsaprabhritiya Adhyaya verse 27. In: Jadavaji Trikamji Aacharya, Editor. Charak Samhita.1st ed. Varanasi: Krishnadas Academy;2000.p.97.&amp;lt;/ref&amp;gt; &amp;lt;br/&amp;gt;&amp;#039;Dhatu vaishamya&amp;#039; means deviation from the state of equilibrium, either increase or decrease of [[Dhatu|dhatus]]. Disproportion of the causative factors results in disequilibrium of the [[Dhatu|dhatus]]. Conversely, the homogeneous causative factors restore the equilibrium state of [[Dhatu|dhatus]]. However, the destruction of the existing [[Dhatu|dhatus]] always happens naturally with time. [Cha.Sa. [[Sutra Sthana|Sutra Sthana]] 16/ 27] &amp;lt;br/&amp;gt;Thus for [[Dhatu|dhatus]] either, they are in the state of equilibrium or disequilibrium, regardless of any cause for destruction, due to their inherent nature, they destroy. For their destruction, no cause is essential or mandatory. It is also clear that the things that are produced (utpanna dravyas) only get destroyed (Bhava vishesha iti utpattimanto vishesha).&amp;lt;ref name=&amp;quot;ref7&amp;quot;&amp;gt;Chakrapani, Charak. Viman Sthana, Cha.5 Srotoviman Adhyaya ver.3. In: Jadavaji Trikamji Aacharya, Editor. Charak Samhita.1st ed. Varanasi: Krishnadas Academy; 2000.p.249. &amp;lt;/ref&amp;gt; One can say that the padartha (matter) produced will get destroyed in the next moment due to its inherent nature.  &amp;lt;br/&amp;gt;Further, Atreya state that there is always a cause for the manifestation [origin of things (&amp;#039;&amp;#039;karya [[Dravya|dravya]]&amp;#039;&amp;#039;)], but none exists for their destruction. However, some scholars believe that the absence of causative factors is the very cause of their destruction. The things which are produced will be eradicated in the second moment.&amp;lt;ref name=&amp;quot;ref8&amp;quot;&amp;gt;Chakrapani, Charak. Sutrasthana, Cha.16 Chikitsaprabhruteeya Adhyaya ver.27. In: Jadavaji Trikamji Aacharya, Editor. Charak Samhita.1st ed. Varanasi: Krishnadas Academy; 2000.p.97. &amp;lt;/ref&amp;gt; There is no need for a different cause to the natural form/nature (innate property). Based on the same principle, the destruction of [[Dhatu|dhatus]] takes place. On the contrary, another group of scholars interprets the same concept in the way that, without a causative factor, it is a cause of destruction.  &amp;lt;br/&amp;gt;The concept of kshanikavada (doctrine of momentariness) is accepted by the scholars of [[Ayurveda|Ayurveda]]. In this context, it is highly pertinent to discuss the role, utility, and importance of chikitsa. Because if the natural resolution (of disorders) is in the very nature of things, then what is the necessity of a qualified physician? Which disequilibrium state of [[Sharira|body]] elements is harmonized by the physician employing therapy? After all, what does the treatment amount to? And what is its objective? Acharya Atreya essentially addresses these queries since the disequilibrium state of [[Dhatu|dhatus]] is not stable (after manifestation in the next moment it vanishes). Because time is constantly moving (nityaga), this fleeting monetary nature of [[Kala|kala]], does not expect any other reason for its destruction.  &amp;lt;br/&amp;gt;The cause of the destruction of things is not known either due to complete absence (just like the horn of a rabbit) or to being incompetent to receive knowledge. Even the truth is not known, like a root nail or other things dug in the earth. In the second example, though  knowledge exists, it is not visible to the naked eye. But in the case of destruction, the cause is not at all present and expected by that respective thing for its destruction. The phenomenon of destruction is inevitable.&amp;lt;ref name=&amp;quot;ref9&amp;quot;&amp;gt;Chakrapani, Charak. Sutrasthana, Cha.16 Chikitsaprabhruteeya Adhyaya ver.31-33. In: Jadavaji Trikamji Aacharya, Editor. Charak Samhita.1st ed.Varanasi: Krishnadas Academy; 2000.p.98. &amp;lt;/ref&amp;gt; There is no cause for its inhibition, nor is there any other action. &amp;lt;br/&amp;gt;Three factors are discussed in the explanation of destruction.   &lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;p style=&amp;#039;text-align:justify;&amp;#039;&amp;gt;Most philosophical schools talk about creation. And further interrogate the cause of the creation, the universe. [[Ayurveda|Ayurveda]] deals with the biological processes, predominantly concerning the human [[Sharira|body]]. This may be why Charak&amp;#039;s treatise discusses the destruction and its place and utility for physicians.  &amp;lt;br/&amp;gt;In the context of the theory of natural destruction, the sequential order of the tetrad suggests the logical progression in the clinical training of [[Ayurveda|Ayurveda]] scholars: from a foundational course in therapeutics to more specialized procedures, including purification therapies.  Kalpana chatushka tetrad describes the planning of purification therapies. It addresses all the aspects regarding the use of medicines for purification purposes. In the last chapter of this tetrad, the signs, and symptoms of excess and less purification are explained, then after swabhavoparam vada is discussed.  &amp;lt;br/&amp;gt;While explaining the importance of purification therapy, it is mentioned that morbid [[Dosha|doshas]] evacuated by purification therapies do not recur. Like plants,  if morbidities are not uprooted completely, the diseases would recur or relapse almost certainly. If the manifestation of the disease is a transient phase and can remit automatically, then what are the objectives and importance of chikitsa? This query has been raised by scholars. In response to this, in the course of explaining the main objectives and applicability of therapy (chikitsa), Acharya Atreya has described the swabhavoparam vada.&amp;lt;ref name=&amp;quot;ref6&amp;quot;&amp;gt;Shivadas Sen, Charak. Sutra Sthana, Cha.16 Chikitsaprabhritiya Adhyaya verse 27. In: Jadavaji Trikamji Aacharya, Editor. Charak Samhita.1st ed. Varanasi: Krishnadas Academy;2000.p.97.&amp;lt;/ref&amp;gt; &amp;lt;br/&amp;gt;&amp;#039;Dhatu vaishamya&amp;#039; means deviation from the state of equilibrium, either increase or decrease of [[Dhatu|dhatus]]. Disproportion of the causative factors results in disequilibrium of the [[Dhatu|dhatus]]. Conversely, the homogeneous causative factors restore the equilibrium state of [[Dhatu|dhatus]]. However, the destruction of the existing [[Dhatu|dhatus]] always happens naturally with time. [Cha.Sa. [[Sutra Sthana|Sutra Sthana]] 16/ 27] &amp;lt;br/&amp;gt;Thus for [[Dhatu|dhatus]] either, they are in the state of equilibrium or disequilibrium, regardless of any cause for destruction, due to their inherent nature, they destroy. For their destruction, no cause is essential or mandatory. It is also clear that the things that are produced (utpanna dravyas) only get destroyed (Bhava vishesha iti utpattimanto vishesha).&amp;lt;ref name=&amp;quot;ref7&amp;quot;&amp;gt;Chakrapani, Charak. Viman Sthana, Cha.5 Srotoviman Adhyaya ver.3. In: Jadavaji Trikamji Aacharya, Editor. Charak Samhita.1st ed. Varanasi: Krishnadas Academy; 2000.p.249. &amp;lt;/ref&amp;gt; One can say that the padartha (matter) produced will get destroyed in the next moment due to its inherent nature.  &amp;lt;br/&amp;gt;Further, Atreya state that there is always a cause for the manifestation [origin of things (&amp;#039;&amp;#039;karya [[Dravya|dravya]]&amp;#039;&amp;#039;)], but none exists for their destruction. However, some scholars believe that the absence of causative factors is the very cause of their destruction. The things which are produced will be eradicated in the second moment.&amp;lt;ref name=&amp;quot;ref8&amp;quot;&amp;gt;Chakrapani, Charak. Sutrasthana, Cha.16 Chikitsaprabhruteeya Adhyaya ver.27. In: Jadavaji Trikamji Aacharya, Editor. Charak Samhita.1st ed. Varanasi: Krishnadas Academy; 2000.p.97. &amp;lt;/ref&amp;gt; There is no need for a different cause to the natural form/nature (innate property). Based on the same principle, the destruction of [[Dhatu|dhatus]] takes place. On the contrary, another group of scholars interprets the same concept in the way that, without a causative factor, it is a cause of destruction.  &amp;lt;br/&amp;gt;The concept of kshanikavada (doctrine of momentariness) is accepted by the scholars of [[Ayurveda|Ayurveda]]. In this context, it is highly pertinent to discuss the role, utility, and importance of chikitsa. Because if the natural resolution (of disorders) is in the very nature of things, then what is the necessity of a qualified physician? Which disequilibrium state of [[Sharira|body]] elements is harmonized by the physician employing therapy? After all, what does the treatment amount to? And what is its objective? Acharya Atreya essentially addresses these queries since the disequilibrium state of [[Dhatu|dhatus]] is not stable (after manifestation in the next moment it vanishes). Because time is constantly moving (nityaga), this fleeting monetary nature of [[Kala|kala]], does not expect any other reason for its destruction.  &amp;lt;br/&amp;gt;The cause of the destruction of things is not known either due to complete absence (just like the horn of a rabbit) or to being incompetent to receive knowledge. Even the truth is not known, like a root nail or other things dug in the earth. In the second example, though  knowledge exists, it is not visible to the naked eye. But in the case of destruction, the cause is not at all present and expected by that respective thing for its destruction. The phenomenon of destruction is inevitable.&amp;lt;ref name=&amp;quot;ref9&amp;quot;&amp;gt;Chakrapani, Charak. Sutrasthana, Cha.16 Chikitsaprabhruteeya Adhyaya ver.31-33. In: Jadavaji Trikamji Aacharya, Editor. Charak Samhita.1st ed.Varanasi: Krishnadas Academy; 2000.p.98. &amp;lt;/ref&amp;gt; There is no cause for its inhibition, nor is there any other action. &amp;lt;br/&amp;gt;Three factors are discussed in the explanation of destruction.   &lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;# Destruction without cause   &lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;# Destruction without cause   &lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
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&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 13:09, 23 February 2023&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l96&quot;&gt;Line 96:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 96:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;https://www.carakasamhitaonline.com/index.php?title=Naveganadharaniya_Adhyaya&amp;amp;oldid=41538. Accessed October 26, 2022. &amp;lt;/ref&amp;gt; &amp;lt;/p&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;https://www.carakasamhitaonline.com/index.php?title=Naveganadharaniya_Adhyaya&amp;amp;oldid=41538. Accessed October 26, 2022. &amp;lt;/ref&amp;gt; &amp;lt;/p&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;== Karmaja vyadhi (diseases due to deeds in a previous life) ==&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;p style=&#039;text-align:justify;&#039;&amp;gt;This is a group of diseases caused by the sinful acts of the previous life. The causative factors for this category of diseases are not at all traceable. The diseases caused by providence (actions of past life) will be relieved only after the effect of such actions, comes to an end (decay of karma).&amp;lt;ref name=&quot;ref41&quot;&amp;gt;Vagbhata. Sutra Sthana, Cha.12 Doshabhedeey Adhyaya verse 58-59. In: Harishastri Paradkar Vaidya, Editors. Ashtanga Hridayam. 1st ed. Varanasi: Krishnadas Academy;2000.p.204. &amp;lt;/ref&amp;gt; The theory of natural destruction appropriately explains the rationale behind this concept.  &amp;lt;/p&amp;gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;== Application in langhana chikitsa and upawasa (reduction therapies and fasting) ==&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;p style=&#039;text-align:justify;&#039;&amp;gt;Fasting is one of the ten methods of langhana therapy.&amp;lt;ref name=&quot;ref42&quot;&amp;gt;Murthy K.N., Deole Y. S.. Langhanabrimhaniya Adhyaya verse18. In: Dwivedi R.B., Deole Y.S., Basisht G., eds. Charak Samhita New Edition. 1st ed. Jamnagar, Ind: CSRTSDC; 2020. &lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt; https://www.carakasamhitaonline.com/mediawiki1.32.1/index.php?title=Langhanabrimhaniya_Adhyaya&amp;amp;oldid = 41152. Accessed October 26, 2022. &amp;lt;/ref&amp;gt; Fasting includes complete abstinence from food. There is extensive empirical and observational evidence that medically supervised fasting is efficacious in treating many disorders. It prevents most chronic degenerative and chronic inflammatory diseases. Michalsen A. mentioned potential health-promoting effects of fasting like fasting-induced neuroendocrine activation and hermetic stress response, increased production of neurotrophic factors, reduced mitochondrial oxidative stress, general decrease of signals associated with aging, and promotion of autophagy.&amp;lt;ref name=&quot;ref43&quot;&amp;gt;Michalsen, A., &amp;amp; Li, C. (2013). Fasting therapy for treating and preventing disease - current state of evidence. Forschende Komplementarmedizin (2006), 20(6), 444–453. https://doi.org/10.1159/000357765 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;ref44&quot;&amp;gt;Wilhelmi de Toledo F, Buchinger A, Burggrabe H, et al. Fasting therapy - an expert panel update of the 2002 consensus guidelines. Forsch Komplementmed. 2013;20(6):434-443. doi:10.1159/000357602https://doi.org/10.1159/000357602 &amp;lt;/ref&amp;gt; &amp;lt;br/&amp;gt;Fasting is a powerful approach to ignite digestion, which removes accumulated toxins in the body. Aam (metabolic toxins) is considered an underlying driver of all illnesses. Fasting destroys many metabolic toxins, removes the obstruction of the srotasa, and ignites the agni (digestive capacity). This process helps to combat illness.&amp;lt;ref name=&quot;ref45&quot;&amp;gt;Gaikwad S, Gaikwad P, Saxena V. Principles of Fasting in Ayurveda. International Journal of Science Environment and Technology (2017), 6 (1), 787-792 &amp;lt;/ref&amp;gt; Fasting therapy works on the fundamentals of swabhavoparama vada. In the absence of cause (unwholesome food), the future manifestation of vishama dhatus is prohibited by abstaining from food intake. The destruction of previously formed aam and vishama dhatu takes place naturally.   &amp;lt;/p&amp;gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;== Application in the cause of diseases ==&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;p style=&#039;text-align:justify;&#039;&amp;gt;The effect of incompatible food is neutralized if taken in a small amount or occasionally.&amp;lt;ref name=&quot;ref46&quot;&amp;gt;Dubey S.D., Singh A.N., Singh A., Deole Y. S.. Atreyabhadrakapyiya Adhyaya ver.106. In: Sirdeshpande M.K., Deole Y.S., Basisht G., eds. Charak Samhita New Edition. 1st ed. Jamnagar, Ind: CSRTSDC; 2020. &lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt; https://www.carakasamhitaonline.com/index.php?title=Atreyabhadrakapyiya_Adhyaya&amp;amp;oldid=41156. Accessed October 27, 2022. &amp;lt;/ref&amp;gt; The equilibrium is disturbed, and diseases are formed only after regular exposure to unwholesome dravya. If unwholesome dravya are consumed occasionally or in very less amounts, it will not result in the manifestation of vishama dhatus. It stresses the importance of maintaining the continuum in manifesting the conditions viz. sama dhatu and vishama dhatu. Continuous practice plays a pivotal role.  &amp;lt;br/&amp;gt;The doctrine of causation (karya-karana siddhanta) has a vital role in the philosophical foundation. The cause-effect theory is accepted by all philosophical schools, including Ayurveda, with different viewpoints. But all stressed the importance of the material cause rather than (as is western philosophy) the efficient cause.&amp;lt;ref name=&quot;ref47&quot;&amp;gt;Apu Sutradhar. Causation in Indian Philosophy. IOSR Journal of Humanities And Social Science 2018 Sept; 23(9) Ver.3: 35-39. DOI: 10.9790/0837-2309033539.  https://www.iosrjournals.org/iosr-jhss/papers/Vol.%2023%20Issue9/Version-3/F2309033539.pdf . &amp;lt;/ref&amp;gt;  This relationship is established despite other principal theories regarding the cause-and-effect relation. And hence for every manifestation, a specific cause is essential. The same is applicable to the continuation of human health. Dhatu vaishamya (disequilibrium state of dhatu) is an effect of exposure to vishama hetu (unwholesome regimens) and, conversely applies to sama dhatus. The things which manifest will undergo destruction due to their inherent nature. There is no need for a separate cause for their destruction. &amp;lt;br/&amp;gt;Swabhavoparama vada explains the importance of intervention and continuous practices of good diet and lifestyle to preserve health and manage diseases.  &amp;lt;/p&amp;gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;big&amp;gt;&amp;#039;&amp;#039;&amp;#039;[[Special:ContactMe|Send us your suggestions and feedback on this page.]]&amp;#039;&amp;#039;&amp;#039;&amp;lt;/big&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;big&amp;gt;&amp;#039;&amp;#039;&amp;#039;[[Special:ContactMe|Send us your suggestions and feedback on this page.]]&amp;#039;&amp;#039;&amp;#039;&amp;lt;/big&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Agnivesha</name></author>
	</entry>
	<entry>
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		<title>Agnivesha at 13:02, 23 February 2023</title>
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		<updated>2023-02-23T13:02:37Z</updated>

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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 13:02, 23 February 2023&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l1&quot;&gt;Line 1:&lt;/td&gt;
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&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{{#seo:&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{{#seo:&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|title=Swabhavoparama vada – Theory of innate destruction&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|title=Swabhavoparama vada – Theory of innate destruction&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
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&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;}}&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;}}&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;/del&gt;&lt;/div&gt;&lt;/td&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-added&quot;&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;p style=&amp;#039;text-align:justify;&amp;#039;&amp;gt;The term &amp;#039;Swabhav&amp;#039; means prakriti or the nature of the substance, and the term &amp;#039;Uparama&amp;#039; means destruction. The word &amp;#039;Swabhavoparama&amp;#039; stands for natural destruction or self-destruction. The theory of natural destruction or process of self-healing is termed &amp;#039;Swabhavoparam-Vada.&amp;lt;ref name=&amp;quot;ref1&amp;quot;&amp;gt;Dhaaniya A, Varsakiya J., Singh NR. Principle of Swabhawoparmwad- Scientific Description Related To Human Body: A Crucial Study. International Ayurvedic Medical Journal (online) 2019 (cited August, 2019); 7: 1334-1338. Available from: http://www.iamj.in/posts/images/upload/1334_1338.pdf. &amp;lt;/ref&amp;gt;  Birth, growth, and senescence, which ultimately lead to death, are inevitable. This physiological event is going on at every moment of our life. Nobody can get rid of this unavoidable process. Destruction is a passive phenomenon as kala (time) moves continuously, passes away, and is irreversible.&amp;lt;/p&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;p style=&amp;#039;text-align:justify;&amp;#039;&amp;gt;The term &amp;#039;Swabhav&amp;#039; means prakriti or the nature of the substance, and the term &amp;#039;Uparama&amp;#039; means destruction. The word &amp;#039;Swabhavoparama&amp;#039; stands for natural destruction or self-destruction. The theory of natural destruction or process of self-healing is termed &amp;#039;Swabhavoparam-Vada.&amp;lt;ref name=&amp;quot;ref1&amp;quot;&amp;gt;Dhaaniya A, Varsakiya J., Singh NR. Principle of Swabhawoparmwad- Scientific Description Related To Human Body: A Crucial Study. International Ayurvedic Medical Journal (online) 2019 (cited August, 2019); 7: 1334-1338. Available from: http://www.iamj.in/posts/images/upload/1334_1338.pdf. &amp;lt;/ref&amp;gt;  Birth, growth, and senescence, which ultimately lead to death, are inevitable. This physiological event is going on at every moment of our life. Nobody can get rid of this unavoidable process. Destruction is a passive phenomenon as kala (time) moves continuously, passes away, and is irreversible.&amp;lt;/p&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l60&quot;&gt;Line 60:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 60:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;# Every manifestation needs cause (cause-effect relationship- karya-karana siddhant)  &lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;# Every manifestation needs cause (cause-effect relationship- karya-karana siddhant)  &lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;# All the things in this universe are momentary (momentariness-kshanika vada) &amp;lt;/p&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;# All the things in this universe are momentary (momentariness-kshanika vada) &amp;lt;/p&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;== Contemporary approach ==&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;=== Apoptosis : ===&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;p style=&#039;text-align:justify;&#039;&amp;gt;In a multicellular organism, the cells are highly organized and regulated too. If cells are no longer needed, they are removed through a tightly regulated cell destruction process. This process is called programmed cell death or apoptosis. Apoptosis (from a Greek word) meaning &quot;falling off,&quot; as leaves from a tree. Apoptosis typically happens in cells that have been around in the body long enough to be worn out, so they need to make way for nice, new young cells. Programmed cell death, including apoptosis is required for normal cell turnover and tissue homeostasis.&amp;lt;ref name=&quot;ref25&quot;&amp;gt;Genetic glossary of National Human Genome Research Institute; Cell Biology; Apoptosis 11; updated on 17th Oct 2022. https://www.genome.gov/genetics-glossary/apoptosis &amp;lt;/ref&amp;gt; In apoptosis a suicide&#039; program is activated within the cell, leading to fragmentation of the DNA, shrinkage of the cytoplasm, membrane changes, and cell death without lysis or damage to neighboring cells. This process shows alteration on the cell surface. This acts as an indicator. In response to this, it was phagocytosed by either a neighboring cell or a macrophage. They can also kill themselves when damaged or stressed by triggering procaspase aggregation and activation from within the cell. Apoptosis is mediated by proteolytic enzymes called caspases, which activate cell death by cleaving specific proteins in the cytoplasm and nucleus.&amp;lt;ref name=&quot;ref26&quot;&amp;gt;Alberts B, Johnson A, Lewis J, et al. Molecular Biology of the Cell. 4th edition. New York: Garland Science; 2002. Programmed Cell Death (Apoptosis) Available from: https://www.ncbi.nlm.nih.gov/books/NBK26873/ &amp;lt;/ref&amp;gt; &amp;lt;br/&amp;gt;Apoptosis, can be activated in physiological or pathological conditions and free the organism from undesired cells. Cell proliferation and physiological cell death are highly coordinated and tightly controlled during normal development. Apoptosis takes part in several processes during embryonic development. It is now apparent that cell death and cell death-like processes are likewise major aspects of gametogenesis, organogenesis, tissue turnover, etc.&amp;lt;ref name=&quot;ref27&quot;&amp;gt;Zakeri Z and Lockshin RA . Cell Death: Defining and Misshaping Mammalian Embryos in: Xiao-Ming Yin, Zheng Dong, Editors. Essentials of Apoptosis- A Guide for Basic and Clinical Research. 2nd edition. Humana Press, a part of Springer Science Business Media, LLC ; 2009.pp 409-423. &amp;lt;/ref&amp;gt; In developing vertebrate nervous systems, for example, up to half or more of the nerve cells normally die soon after they are formed. In a healthy adult human, billions of cells die in the bone marrow and intestine every hour. In adult tissues, cell death exactly balances cell division. If this were not so, the tissue would grow or shrink. During the metamorphosis of a tadpole into a frog, since tail is not required, the cells in the tail undergoes apoptosis. Thus, we can say that the regulation of cell death is as necessary as the regulation of cell life to maintain a healthy individual.&amp;lt;ref name=&quot;ref28&quot;&amp;gt;Mondello, C., &amp;amp; Scovassi, A. I. (2010). Apoptosis: a way to maintain healthy individuals. Sub-cellular biochemistry, 50, 307–323. https://doi.org/10.1007/978-90-481-3471-7_16 &amp;lt;/ref&amp;gt; &amp;lt;br/&amp;gt;In the context of the human body, apoptosis can be based on the theory of swabhavoparama vada.1 Both of these physiological processes converge to the point of `self-destruction&#039;. Apoptosis is a highly regulated and controlled process that confers advantages during an organism&#039;s lifecycle. Homeostasis is necessary to maintain health, but the natural death of every living object is inevitable. So, the cells adopt the mechanism of programmed cell death. In adulthood, about 10 billion cells die every day to keep balance with the number of new cells arising from the body&#039;s stem cell populations. This normal homeostasis is not just a passive process but is regulated through apoptosis.&amp;lt;ref name=&quot;ref29&quot;&amp;gt;Renehan AG, Booth C, Potten CS. What is apoptosis, and why is it important? BMJ. 2001 Jun 23;322(7301):1536-8. doi: 10.1136/bmj.322.7301.1536. PMID: 11420279; PMCID: PMC1120576. &amp;lt;/ref&amp;gt; &amp;lt;/p&amp;gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;=== Autophagy: ===&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;p style=&#039;text-align:justify;&#039;&amp;gt;Exclusively in eukaryotic cells, the lysosomal degradation of intracellular components is termed &#039;autophagy&#039;. It helps the cell to adapt to a changing environment. Autophagy plays an essential role in maintaining cellular homeostasis, and dysregulation may participate in the pathological process of many human diseases. Autophagy is responsible for degrading long-lived proteins and damaged or superfluous organelles. Autophagy is also part of the cellular response to intracellular and extracellular stress. This process plays an important role in cellular protein metabolism, waste removal, structural reconstruction, growth, and development. Under stress conditions such as starvation and hypoxia, it can be induced quickly. This regulation is achieved through post-translational modifications (such as phosphorylation and acetylation) of key autophagy proteins. &amp;lt;br/&amp;gt;This promotes proteolytic degradation of cytosolic components at the lysosome. The isolation membrane, phagophore expands to engulf intra-cellular cargo, such as protein aggregates, organelles, and ribosomes, thereby restoring them in an autophagosome. The loaded autophagosome matures through fusion with the lysosome, promoting the degradation of autophagosome contents by lysosomal acid proteases. Lysosomal permeases and transporters export amino acids, nucleotides, and other by-products of degradation back out to the cytoplasm, where cells can re-use. Thus, autophagy may be considered a cellular&#039; recycling factory&#039; that promotes energy efficiency through ATP generation and mediates damage control by removing non-functional proteins and organelles.  &amp;lt;br/&amp;gt;Chaperone-mediated autophagy (CMA) refers to a special type of autophagy that selectively degrades certain proteins with the assistance of chaperones. The soluble protein substrate in the cytoplasm can directly enter the lysosome. Dice discovered that lysosomes could selectively degrade ribonuclease A (RNase A).&amp;lt;ref name=&quot;ref30&quot;&amp;gt;Anding AL, Baehrecke EH. Cleaning house: selective autophagy of organelles. Dev Cell. 2017;41:10–22. &amp;lt;/ref&amp;gt;  LAMP2A (lysosome-associated membrane protein type 2A) on the lysosomal membrane is the receptor, one of the key regulators involved in this selective degradation pathway.&amp;lt;ref name=&quot;ref31&quot;&amp;gt;Kaushik S, Cuervo AM. Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis. Nat Cell Biol. 2015;17:759–70. &amp;lt;/ref&amp;gt; LAMP2A is considered to be the primary rate-limiting factor of CMA. Studies have shown that starvation, oxidative stress, DNA damage, hypoxia, and other stimuli can increase the activity of CMA by promoting the production of the LAMP2A protein. A high-fat diet can reduce the level of LAMP2A on the lysosomal membrane and thus inhibits CMA activity in the liver. A series of studies have demonstrated that CMA plays a significant role in maintaining neuronal homeostasis, promoting lipid degradation, protecting mitochondrial function, and repairing DNA damage. The CMA activity decreases in aging bodies, mainly due to the decreased level of LAMP2A in the lysosomes, which may underlie the development of aging-related diseases such as Parkinson&#039;s disease, Alzheimer&#039;s disease, metabolic disorders, and tumors.&amp;lt;ref name=&quot;ref32&quot;&amp;gt;Cuervo AM, Wong E. Chaperone-mediated autophagy: roles in disease and aging. Cell Res. 2014;24:92–104 &amp;lt;/ref&amp;gt; Fasting therapy works on the principles of autophagy.&amp;lt;ref name=&quot;ref33&quot;&amp;gt;Mattson MP, Longo VD, Harvie M. Impact of intermittent fasting on health and disease processes. Ageing Res Rev. 2017;39:46-58. doi:10.1016/j.arr.2016.10.005&amp;lt;/ref&amp;gt; &amp;lt;/p&amp;gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;== Importance and utility of the swabhavoparama vada  ==&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;p style=&#039;text-align:justify;&#039;&amp;gt;Swabhavoparama vada ascertains the importance of chikitsa and the duties of a qualified physician. The concept also emphasizes to disrupt the continuum of the cause (Hetoh avartanam) which is removing the causative factors (hetus). It creates the absence of causative factors called &#039;nidana-varjana&#039;. Ithampers the progression of the disease. &amp;lt;br/&amp;gt;Abstinence from disease-causing factors has preventive and curative aspects. Nidana parivarjana plays a vital role in breaking down the pathogenesis at every stage of shat - kriyakala.&amp;lt;ref name=&quot;ref34&quot;&amp;gt;Baghel M.S., Mandal S.K.. Vyadhita Rupiya Vimana Adhyaya verse 28. In: Khandel S.K., Bhagwat M., Deole Y.S., Basisht G., eds. Charak Samhita New Edition. 1st ed. Jamnagar, Ind: CSRTSDC; 2020.  &lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;https://www.carakasamhitaonline.com/index.php?title=Vyadhita_Rupiya_Vimana&amp;amp;oldid=41176. Accessed October 25, 2022. &amp;lt;/ref&amp;gt; It can be included under non-drug therapy (adravyabhoota chikitsa). It can easily conceal the manifestation of vishama dhatus and break the pathogenesis chain.&amp;lt;ref name=&quot;ref35&quot;&amp;gt;Chauhan P,Vyas M, Bhojani MK, Pathak P. A Conceptual Study on Swabhavoparam Vada in context to Nidana Parivarjana with special reference to its mechanism useful in Madhumeha (Type 2 Diabetes Mellitus). International Journal of Ayurveda and Pharma Research. 2020;8(4):77-82. &amp;lt;/ref&amp;gt;&amp;lt;br/&amp;gt;Dosha, dhatu, and malas are the fundamental units of the body. Physiology is governed by these three units. The annihilation process is a continuous phenomenon. Thus,  kshaya or destruction of these elements occurs naturally without any cause. Utpatti or manifestation of these units expect cause. To restore and continue the state of equilibrium of all the dhatus is the prime objective of Ayurveda. All types of actions and procedures are prescribed for the very objective.&amp;lt;ref name=&quot;ref36&quot;&amp;gt;Singh R.H., Singh G., Sodhi J.S., Dixit U.. Deerghanjiviteeya Adhyaya verse 53. In: Dixit U., Deole Y.S., Basisht G., eds. Charak Samhita New Edition. 1st ed. Jamnagar, Ind: CSRTSDC; 2020. &lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt; https://www.carakasamhitaonline.com/index.php?title=Deerghanjiviteeya_Adhyaya&amp;amp;oldid=41131. Accessed October 25, 2022. &amp;lt;/ref&amp;gt; The doctrine of swabhavoparama vada helps to accomplish this. &amp;lt;br/&amp;gt;The same elements, whose wholesome combination gives rise to the well-being of human beings (purusha), bring about various kinds of diseases when combined in an unwholesome manner. [Cha.Sa.SutraSthana 25/29]   &amp;lt;br/&amp;gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;Qualities of the fundamental elements (panchamahabhuta) are responsible for the equilibrium state of all the units of the body, thus maintaining the state of equilibrium of dhatus. While the negative (opposite) qualities of the same mahabhuta lead to various diseases.&amp;lt;ref name=&quot;ref37&quot;&amp;gt;Chakrapani, Charak. Sutra Sthana, Cha.25 Yajjapurusheeya Adhyaya verse 29. In: Jadavaji Trikamji Aacharya, Editor. Charak Samhita.1st ed. Varanasi: Krishnadas Academy;2000.p.129. &amp;lt;/ref&amp;gt; It is in accordance with the theory of swabhavoparama vada.   &amp;lt;/p&amp;gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;== Utility of the concept ==&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;p style=&#039;text-align:justify;&#039;&amp;gt;A physician must know the characteristics of panchamahabhuta, body components, food, and various therapeutic medicines. Observation of the changes in characteristics with an objective to maintain equilibrium status makes a successful treatment. The food items that continue an equilibrium state in dhatus and help eliminate abnormalities or disturbances in the equilibrium path are considered wholesome food items. Everything expects the cause for its manifestation (utpatti). Wholesome food items are the inherent or the intimate cause (upadana karana) for the manifestation of dhatus. Regular consumption of such dravya also helps to disrupt the continuum of vitiated dhatus and restore the state of equilibrium. Maintaining this continuum of equilibrium of dhatu is essential for preserving health. Thus, the destruction of previously vitiated dhatus will take place by swabhava. Further continuous consumption of a wholesome diet will lead to the formation and maintenance continuum of the equilibrium state of dhatus (sama dhatu santan-parampara). &amp;lt;/p&amp;gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;=== Sharira as an example: ===&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;p style=&#039;text-align:justify;&#039;&amp;gt;As per the definition of sharira (body), it naturally degenerates every moment. This supports the theory of natural destruction. &amp;lt;/p&amp;gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;== Application in understanding the root cause of pleasure and diseases ==&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;p style=&#039;text-align:justify;&#039;&amp;gt;In chapter on Purush Vichayya Sharira, the cause of pravritti (utpatti –attachment)) and methods of nivritti (detachment) are discussed. Acharya Atreya stated that&amp;lt;ref name=&quot;ref38&quot;&amp;gt;Awasthi H.H., Singh R., Deole Y. S.. Purusha Vichaya Sharira Adhyaya ver.8. In: Bhalerao S., Deole Y.S., Basisht G., eds. Charak Samhita New Edition. 1st ed. Jamnagar, Ind: CSRTSDC; 2020. https://www.carakasamhitaonline.com/index.php?title=Purusha_Vichaya_Sharira&amp;amp;oldid=41182. Accessed October 27, 2022. &amp;lt;/ref&amp;gt; the division of the six elements, the separation, the withdrawal of the living, the restraint of the life force, and that destruction is the nature of the world. Here, it is reiterated that cause is essential for the manifestation of being, but destruction is natural. The source of attachment is ignorance, desire, hatred, and purposeful action. [Cha. Sa. Sharira Sthana 6/5] They are the causes of manifestation. This reminds us of Buddha&#039;s philosophy&#039;s theory of impermanence and momentariness. Simultaneously, there is an increase and decrease in the dhatus of opposite properties. The natural factors maintain the state of equilibrium. When some factors increase dhatu, the other opposite factors in the body reduce them up to normal level. When properly administered simultaneously, medical therapies bring both the reduced and increased dhatus to their normal states by reducing the increased ones and increasing the diminished ones.  &amp;lt;/p&amp;gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;== Application in the preservation of equilibrium status ==&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;p style=&#039;text-align:justify;&#039;&amp;gt;In response to the Agnivesh&#039;s question on managing illnesses of the past, the present, and the future, Acharya Atreya has reiterated the principle of swabhavoparam vada &amp;lt;ref name=&quot;ref39&quot;&amp;gt;Dwivedi R.B., Gujarathi R.. Katidhapurusha Sharira Adhyaya verse92-94. In: Bhalerao S., Deole Y.S., Basisht G., eds. Charak Samhita New Edition. 1st ed. Jamnagar, Ind: CSRTSDC; 2020. https://www.carakasamhitaonline.com/index.php?title=Katidhapurusha_Sharira&amp;amp;oldid=41650. Accessed January 7, 2023. &amp;lt;/ref&amp;gt;. When treatment is given conducive to the continuity of happiness (health), the pleasure (sukha) is continued. Natural destruction destroys suffering in the form of disease. Due to the absence of a cause of suffering, the suffering (illness) will not arise. [Cha. Sa. Sharira Sthana 1/93] Because of the momentary nature of elements (bhava –padartha), neither the state of equilibrium of dhatus, nor the imbalanced state of dhatus is brought to normalcy.  The causative factors determine the equilibrium or imbalance of the dhatus. &amp;lt;/p&amp;gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;== Relation with vishesha principle ==&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;p style=&#039;text-align:justify;&#039;&amp;gt;The swabhavoparama vada can be considered in the light of another principle quoted by Charak i.e. Hraasa hetuh visheshacch. [Cha.Sa. Sutra Sthana 1/44] The dis-similar or opposite substance or action or properties cause a reduction. At first sight, these two principles seem contradictory because if destruction is the natural process, then what is the need for the vishesha principle? If dhatus are vitiated due to excessive increase (dhatu vriddhi avastha), the physician will use the vishesha principle to resume the equilibrium state of dhatus. As per the swabhavoparama vada, natural destruction is a continuous process due to the momentary nature of dhatus. Hence for destruction, no medicine is needed. But intervention is required to break the chain of manifestation of vitiated dhatus. In the present case, the vishesha principle should be used to restore the equilibrium of dhatus. Charak illustrates the same in the explanation of swabhavoparama vada. [Cha. Sa. Sutra Sthana 16/34-36] &amp;lt;/p&amp;gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;== Swabhavika vyadhi (naturally occurring diseases) ==&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;p style=&#039;text-align:justify;&#039;&amp;gt;Swabhava (nature) is a cause behind many specific phenomenon. Death is a natural phenomenon. Naturally occurring diseases due to swabhava (nature) depend on kala (time). Examples are kshudha (hunger), pipasa (thirst), jaravastha (aging), and mrityu (death). Sushruta states that the swabhavik vyadhi (natural diseases) like jara (ageing), mrityu (death) occur without reason as the time (kala) proceeds. Thee are unavoidable. Swabhavoparama vada is the doctrine used to explain the destruction phenomenon.  &amp;lt;/p&amp;gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;== Padamshika krama (sequence to adopt good habits and discard bad habits) ==&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;p style=&#039;text-align:justify;&#039;&amp;gt;This is a good example of  swabhawoparama vada. A sequential regimen is prescribed to adopt good habits and gradually give up bad habits. By gradually reducing unwholesome practices and adopting the wholesome practices in proper sequence, the unwholesome practices will not recur and wholesome will be fully adopted. The continuum of the disequilibrium stage of dhatus (vishama dhatus) will be destroyed. This will prevent the recurrence of vitiated dosha and expedite recovery from the disease state. Such practice establishes the need and importance of maintaining the continuum of wholesome practices.&amp;lt;ref name=&quot;ref40&quot;&amp;gt;Deole Y. S.. Naveganadharaniya Adhyaya verse 36-38. In: Reddy P.S., Deole Y.S., Basisht G., eds. Charak Samhita New Edition. 1st ed. Jamnagar, Ind: CSRTSDC; 2020.   &lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;https://www.carakasamhitaonline.com/index.php?title=Naveganadharaniya_Adhyaya&amp;amp;oldid=41538. Accessed October 26, 2022. &amp;lt;/ref&amp;gt; &amp;lt;/p&amp;gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;big&amp;gt;&amp;#039;&amp;#039;&amp;#039;[[Special:ContactMe|Send us your suggestions and feedback on this page.]]&amp;#039;&amp;#039;&amp;#039;&amp;lt;/big&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&amp;lt;big&amp;gt;&amp;#039;&amp;#039;&amp;#039;[[Special:ContactMe|Send us your suggestions and feedback on this page.]]&amp;#039;&amp;#039;&amp;#039;&amp;lt;/big&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Agnivesha</name></author>
	</entry>
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